Knowledge of Asian monsoon variability remains limited because of sparse instrumental data available only for short time series. Here, an updated tree-ring width record covering the period ad 1037–2009 was developed for the south-central Tibetan Plateau (TP). Correlation analysis revealed a significant relationship ( r = 0.71) between the tree-ring index and annual (previous July to current June) precipitation series for the instrumental period 1963–2008, which accounts for 50.41% of the rainfall variability. Based on a linear regression model, the longest available regional precipitation history was reconstructed. Spatial correlation between tree ring width and annual precipitation data from previous July to current June indicates that the reconstruction is representative of precipitation changes on the south-central TP. Regional wet conditions occurred during ad 1095–1161, 1376–1403, 1414–1446, 1518–1537, 1549–1572, 1702–1757, 1848–1878 and 1891–1913, while dry periods were identified during ad1189–1242, 1256–1314, 1329–1357, 1470–1491, 1573–1623, 1636–1686, 1761–1821, 1823–1847, 1879–1890 and 1931–1985. The negative correlation between our reconstructed precipitation and India monsoon rainfall series indicates the seesaw pattern over northern and southern monsoon Asia. It is suggested that solar radiation-induced sea surface temperature (SST) anomalies over the tropical Pacific influence regional rainfall patterns. The degree of this influence has been stable at the multidecadal scale during the past 1000 years.