Trends in Acute Myocardial Infarction Incidence and Mortality Over 30 Years in Japan: Report From the MIYAGI-AMI Registry Study

Takii, Toru; Yasuda, Satoshi; Takahashi, Jun; Ito, Kei; Shiba, Nobuyuki; Shirato, Kunio; Shimokawa, Hiroaki

doi:10.1253/circj.cj-09-0619

Cited by 179 publications

(126 citation statements)

References 30 publications

(32 reference statements)

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“…(16) AMI is one of the leading causes of mortality worldwide. (17,18) The results of the current study indicate that, after adjustment for potential confounding factors, hip fracture is independently associated with a 29% increase in risk of developing AMI compared with controls. In addition, the risk of AMI after hip fracture is more prominent in elderly patients, women, and in patients with other underlying diseases.…”

Section: Discussionmentioning

confidence: 56%

Hip fracture and risk of acute myocardial infarction: A nationwide study

Chiang

Liu

Chen

et al. 2012

Journal of Bone and Mineral Research

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Osteoporotic fractures are associated with increased mortality risk. However, little data are available on the risk of acute myocardial infarction (AMI) after hip fracture. Therefore, we investigated whether hip fracture increased the risk of AMI in a large, nationwide cohort study. We obtained data from 8758 patients diagnosed with hip fracture from 2000 to 2009 and from 4 matched controls for each patient from the Longitudinal Health Insurance Database (LHID 2000), Taiwan. Controls were matched for age, sex, comorbid disorders, and enrollment date. All subjects were followed up from the date of enrollment until AMI, death, or the end of data collection (2009). Cox's regression model adjusted for age, sex, comorbid disorders, and medication was used to assess independent factors determining the risk of development of AMI. As expected, despite the matching, the hip fracture patients had more risk factors for AMI at baseline. A total of 8758 subjects with hip fractures and 35,032 controls were identified. Among these patients, 1183 (257 hip fracture patients and 926 controls) developed AMI during the median 3.2-year (interquartile range 1.4 to 5.8 years) follow-up period. Patients with hip fractures had a higher incidence of AMI occurrence when compared with controls (8.7/1000 person-years versus 6.82/1000 person-years). Multivariate analysis adjusted for baseline covariates indicated that hip fracture was associated with a greater risk for AMI development (hazard ratio [HR] ¼ 1.29; 95% confidence interval [CI] 1.12-1.48; p < 0.001). We conclude that hip fracture is independently associated with a higher risk of subsequent AMI. ß

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Section: Discussionmentioning

confidence: 56%

Hip fracture and risk of acute myocardial infarction: A nationwide study

Chiang

Liu

Chen

et al. 2012

Journal of Bone and Mineral Research

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“…Due to the improvement of medical equipment and medical care, the mortality of AMI is decreasing. However, a steadily increasing incidence rate of AMI can still be observed (Takii et al 2010). Therefore, there is an increased need for conducting research to identify the factors that affect the survival and prognosis of patients with AMI following percutaneous coronary intervention (PCI).…”

Section: Introductionmentioning

confidence: 99%

Prognostic Factors for In-Hospital and Long-Term Survival in Patients with Acute ST-Segment Elevation Myocardial Infarction after Percutaneous Coronary Intervention

Hou

Gao

Feng

et al. 2017

Tohoku J. Exp. Med.

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Acute ST segment elevation myocardial infarction (STEMI) is one of the causes of death and disability in patients with cardiovascular diseases. This study aimed to investigate the prognostic factors of in-hospital and long-term survival in patients with acute STEMI undergoing percutaneous coronary intervention (PCI). Patients with STEMI undergoing PCI were divided into the death group (n = 54) and the survival group (n = 306) based on the outcomes during hospitalization. The routine blood and biochemistry tests, Killip classes and global registry of acute coronary events (GRACE) risk score were detected. The 1-, 2-and 3-year survival rates after PCI was observed through a 3-year follow-up. The survival factors, survival rates and multivariate analyses were conducted using Logistic regression analysis, Kaplan-Meier survival analysis and Cox proportional hazards regression. The incidence of cardiogenic shock and anterior wall MI (AWMI), the serum levels of γ-glutamyl endopeptidase (γ-GGT) and creatine kinase isoenzyme MB (CK-MB), Killip classes and GRACE risk score were higher in the death group, compared with the survival group. AWMI, cardiogenic shock, high serum levels of γ-GGT and CK-MB, Killip class III-IV and high GRACE risk scores were associated with in-hospital mortality. AWMI, cardiogenic shock, Killip class III-IV and high GRACE risk scores were correlated with a poor long-term survival. Our findings have demonstrated that AWMI, cardiogenic shock, high serum levels of γ-GGT and CK-MB, Killip class III-IV, and high GRACE risk scores are risk factors for in-hospital and long-term prognosis of acute STEMI patients.

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“…1). At present, the absolute risk (incidence and mortality) of CAD in Japan is much lower than that observed in Western countries [14][15][16][17] ; however, due to recent increases in the LDL-C and TC levels in Japanese individuals as a result of Westernization of the Japanese lifestyle 18,19) , and the findings of a report showing that the incidence of CAD is increasing in some regions of Japan 19,20) , there is concern that the incidence of CAD will rise throughout Japan. Therefore, these guidelines define diagnostic criteria for assessing dyslipidemia during screening to prevent the development of arteriosclerosis from the perspective of preventing CAD, as shown in Table 1.…”

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confidence: 99%