Trends in corneal transplantation in a single center in Barcelona, Spain. Transitioning to DMEK

Palma-Carvajal, F; Morales, Pablo Franquelo; Salazar-Villegas, Á.; Figueroa-Vercellino, J.P.; Spencer, Frank R.; Peraza‐Nieves, Jorge; Sabater, N.; Torras, Jaume

doi:10.1016/j.jfo.2019.06.026

Cited by 12 publications

(8 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Interestingly, the introduction of DMEK to NZ in 2015 did not significantly affect the proportion of DS(A) EKs being performed, unlike observations in Spain, 17 Canada, 4 and Germany. 3 This may be, in part, due to the NZNEB precutting DS(A)EK tissue but does not yet preprepare DMEK tissue, and there are fewer surgeons in NZ who perform DMEK surgery; during the study period, there were 9 surgeons who performed DMEK (n = 99 surgeries) compared with 19 surgeons who performed DS(A)EK (n = 954 surgeries).…”

Section: Discussionmentioning

confidence: 64%

“…16 The number of corneal transplants performed per population more than doubled increasing from 2.55/100,000 population/year to 6.06/100,000 population/year, a similar trend to that observed overseas. 17 However, in addition to NZ's dramatic 41% increase in population, 3 additional factors might have significantly influenced trends in keratoplasty: increased number of cataract surgeries with improving phacoemulsification technology, introduction of endothelial keratoplasty with lower clinical threshold for surgery, and the use of CXL for keratoconus that might obviate future keratoplasty in many cases.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Changing Trends in Corneal Transplantation in Aotearoa/New Zealand, 1991 to 2020: Effects of Population Growth, Cataract Surgery, Endothelial Keratoplasty, and Corneal Cross-Linking for Keratoconus

Chilibeck

Brookes

Gokul

et al. 2021

Cornea

View full text Add to dashboard Cite

The purpose of this study was to identify trends in the primary indication for keratoplasty in New Zealand/Aotearoa (NZ) after significant population growth, increase in the number of cataract surgeries per population, widespread adoption of endothelial keratoplasty, and introduction of corneal crosslinking for keratoconus.Methods: Statistical analysis of the New Zealand National Eye Bank's prospective database of all keratoplasties was performed between January 1991 and January 2020. Indications for keratoplasty were isolated for the primary diagnosis.Results: In total, 6840 corneas were transplanted with mean 236 6 57.5 transplants/year, increasing from 2.55 to 6.06 per 100,000 NZ population/year. Over the past decade, the number of transplant recipients aged 60 years or older has increased and recipients aged 20 to 39 years have plateaued. In 2019, for the first time, regraft became the most common indication (30.9%), followed by keratoconus (27.9%) and corneal dystrophy (18.8%), with a steady decline in bullous keratopathy. Proportions of the keratoplasty technique changed dramatically: penetrating keratoplasty fell from 91.4% in 2006 to 55.0% in 2019, Descemet's stripping endothelial keratoplasty increased from 0% to 29.5%, anterior lamellar keratoplasty increased from 2.5% to 5.7%, and Descemet membrane endothelial keratoplasty increased from 0% to 9.1%.Conclusions: Keratoplasty trends in Aotearoa/NZ have changed considerably because of the evolution of phacoemulsification and keratoplasty techniques. Unlike proportions observed overseas, NZ still performs penetrating keratoplasties in over half of all transplants. Corneal cross-linking may be having an early effect of reducing keratoplasty rates for keratoconus.

show abstract

Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 99%

Changing Trends in Corneal Transplantation in Aotearoa/New Zealand, 1991 to 2020: Effects of Population Growth, Cataract Surgery, Endothelial Keratoplasty, and Corneal Cross-Linking for Keratoconus

Chilibeck

Brookes

Gokul

et al. 2021

Cornea

View full text Add to dashboard Cite

show abstract

“…This shift was even more important after the introduction of precut tissue for DMEK in 2017 [6]. Some studies [3] have already highlighted an increased trend to perform EK after precut tissue introduction. It is commonly thought that surgeons are more prone to perform posterior lamellar techniques when the risk to damage corneal tissue-due to manual preparation-is very low [28,29].…”

Section: Plos Onementioning

confidence: 99%

“…However, epidemiology on such surgeries is not always easy and mostly depends on regional eye bank report services. Moreover, several studies suggest most surgeons tend to customize indications and even perform more posterior lamellar techniques when eye bank precut tissue is available [2,3].…”

Section: Introductionmentioning

confidence: 99%

“…In 2013, it started to supply precut tissue for Descemet Stripping Automated Endothelial Keratoplasty (DSAEK), and from 2017, precut tissue for Descemet Membrane Endothelial Keratoplasty (DMEK) was distributed [6]. Despite few surgeons started to perform endothelial keratoplasties (EK) before 2013, from that date, more and more surgeons dared to switch to posterior lamellar techniques due to the availability of precut tissue [3].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Corneal transplantation activity in Catalonia, Spain, from 2011 to 2018: Evolution of indications and surgical techniques

et al. 2021

View full text Add to dashboard Cite

Purpose To report corneal transplant activity carried out in Catalonia (Spain) and the evolving indications for keratoplasty over an 8-year period. Methods Annual reports from the Catalan Transplant Organization, Spain, on corneal graft indications and techniques from 2011 to 2018 were reviewed. Results A total of 9457 keratoplasties were performed in Catalonia, from January 2011 to December 2018. The most frequent indications were bullous keratopathy (BK; 20.5%), Fuchs endothelial dystrophy (FED; 17.9%), re-graft (13.7%), and keratoconus (11.3%). Penetrating keratoplasty (PKP) accounted for 63.4% of all performed keratoplasties. Since the introduction of eye bank precut tissue for Descemet stripping automated endothelial keratoplasty (DSAEK) in 2013 and for Descemet membrane endothelial keratoplasty (DMEK) in 2017 the number of endothelial keratoplasties has drastically increased. An increasing trend of posterior lamellar techniques over the total of keratoplasties was found (p<0.001). Endothelial keratoplasties for different endothelial diseases indications (BK, FED, and re-graft), also showed and increasing trend (p<0.001). DMEK is the technique with the highest increase (statistically significantly different from linearity) over other endothelial keratoplasties in FED (p<0.001) but not in BK (p = 0.67) or re-grafts (p = 0.067). Conclusion Endothelial diseases represented the top indication for keratoplasty over the 8-year period. PKP is still the most used technique in Catalonia, but endothelial keratoplasties and especially DMEK showed a significant increasing trend over the last years. This is congruent with the main rationale nowadays for keratoplasties: to customize and transplant as less tissue as possible. Therefore, the availability of precut tissue could have definitely enforced such approach.

show abstract

Endothelial Cell Loss After Descemet's Membrane Endothelial Keratoplasty for Fuchs' Endothelial Dystrophy: DMEK Compared to Triple DMEK

Shahnazaryan

Sese

Hollick

2020

American Journal of Ophthalmology

View full text Add to dashboard Cite

Trends in corneal transplantation in a single center in Barcelona, Spain. Transitioning to DMEK

Cited by 12 publications

References 23 publications

Changing Trends in Corneal Transplantation in Aotearoa/New Zealand, 1991 to 2020: Effects of Population Growth, Cataract Surgery, Endothelial Keratoplasty, and Corneal Cross-Linking for Keratoconus

Changing Trends in Corneal Transplantation in Aotearoa/New Zealand, 1991 to 2020: Effects of Population Growth, Cataract Surgery, Endothelial Keratoplasty, and Corneal Cross-Linking for Keratoconus

Corneal transplantation activity in Catalonia, Spain, from 2011 to 2018: Evolution of indications and surgical techniques

Endothelial Cell Loss After Descemet's Membrane Endothelial Keratoplasty for Fuchs' Endothelial Dystrophy: DMEK Compared to Triple DMEK

Contact Info

Product

Resources

About