Trends in the lifetime risk of developing cancer in Great Britain: comparison of risk for those born from 1930 to 1960

Ahmad, Amar; Ormiston‐Smith, Nick; Sasieni, Peter

doi:10.1038/bjc.2014.606

Cited by 224 publications

(172 citation statements)

References 10 publications

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“…The global cancer burden is expected to increase,9 and a recent study from Great Britain has reported the lifetime risk to be 1 in 2 among individuals born since 1960 10. Furthermore, the emotional distress and economic cost of cancers are immense and most likely rising 11.…”

Section: Introductionmentioning

confidence: 99%

Atrial Fibrillation and Risk of Cancer: A Danish Population‐Based Cohort Study

Vinter

Christesen

Fenger‐Grøn

et al. 2018

JAHA

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BackgroundAtrial fibrillation (AF) and cancer are frequent diseases worldwide. The timewise association between the diagnosis of AF and a subsequent diagnosis of cancer may clarify whether a mutual cause exists, and may also guide clinicians about time windows of high risk of cancer occurrence.Methods and ResultsWe conducted a population‐based cohort study among 26 222 men and 28 879 women free of AF and cancer at baseline based on the Danish Diet, Cancer and Health study. The participants were followed for the development of AF (the Danish National Patient Registry) and subsequent cancer (the Danish Cancer Registry) until 2013. We used Cox proportional hazard models with new‐onset AF as time‐dependent exposure. The men (median age 56 years) and women (median age 56 years) were followed for medians of 16.7 and 19.6 years, respectively. AF was associated with higher risks of any type of cancer (men: hazard ratio [HR] 1.41, 95% confidence interval [CI], 1.26–1.58; women: HR 1.15, 95% CI, 1.02–1.32), and for men only, lung (HR 1.66, 95% CI, 1.19–2.30), and colorectal cancer (HR 1.37, 95% CI, 1.02–1.85). Within the initial 90 days following the diagnosis of AF, the risks of any type of cancer (men: HR 2.89, 95% CI, 2.10–3.98; women: HR 3.72, 95% CI, 2.49–5.56), lung (men: HR 7.70, 95% CI, 4.34–13.68; women: HR 7.98, 95% CI, 3.96–16.09), and colorectal cancer (men: HR 3.35, 95% CI, 1.03–10.90; women: HR 5.91, 95% CI, 2.44–14.29) were higher for men and women.ConclusionsA diagnosis of AF is associated with a higher incidence rate of cancer among men and women. The cancer incidence rate is particularly elevated within 90 days after the diagnosis of AF.

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Section: Introductionmentioning

confidence: 99%

Atrial Fibrillation and Risk of Cancer: A Danish Population‐Based Cohort Study

Vinter

Christesen

Fenger‐Grøn

et al. 2018

JAHA

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“…It is estimated that one in two people in Great Britain will develop some form of cancer during their lifetime [1]. In 2014, 357,000 new cases of cancer were diagnosed in the UK and the rate of incidence is increasing [2].…”

Section: The Use Of Mobile Devices To Help Patients With Cancer To Mementioning

confidence: 99%

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confidence: 99%

Use of Mobile Devices to Help Cancer Patients Meet Their Information Needs in Non-Inpatient Settings: Systematic Review (Preprint)

Richards¹,

Kinnersley²,

Brain³

et al. 2018

Preprint

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The use of mobile devices to help patients with cancer to meet their information needs in non-inpatient settings: A systematic review IntroductionIt is estimated that one in two people in Great Britain will develop some form of cancer during their lifetime [1]. In 2014, 357,000 new cases of cancer were diagnosed in the UK and the rate of incidence is increasing [2]. However, survival rates have doubled in the UK in the last 40 years and so, for many, cancer is a chronic condition with which they live for many years. Subsequently, there has been a shift from inpatient to outpatient and community cancer care, where patients are required to manage their condition at home, away from regular supervision by clinicians. This change in care requires patients to take a more active role in their treatment and survivorship. Patients are often faced with an uncertain future, unfamiliar tests and procedures, complex decisions about treatment options, treatment-related side-effects and lifestyle changes. In order to take a more active role in their care, and to cope with and manage these changes to daily life, patients require relevant information [3,4]. Research has established that patients have a wide range of information needs throughout their illness. Reviews of these studies suggest that patients generally want information on the extent of the disease, likelihood of cure and prognosis, available treatments, side-effects of treatment, self-care and return to normal life [5][6][7]. Other, less urgent, information needs include the impact of cancer and/or treatment on social activities, family and friends, mental wellbeing and sexual activity, and the risk of family and friends getting cancer [5,6]. There is evidence to suggest that information may help to reduce uncertainty, provide patients with a sense of control over their lives and support informed decision-making about treatment options [8,9]. While many people with cancer want as much information as possible about their condition [10], up to 93% of cancer patients across the US, Europe and the UK report having unmet information needs [11][12][13][14].The introduction of Smart technology has provided a new platform for delivering information-based interventions to patients. Approximately 93% of adults in the UK now personally own or use a mobile phone, of whom 71% specify that they own a Smartphone [15]. Similarly, over two thirds of adults in the UK now own or have access to a tablet computer [15]. Similar statistics of Smart device ownership and use have been reported in cancer patient populations [16,17]. Mobile devices therefore offer the potential for wide reach at the point of need for patients with cancer. Several existing systematic and scoping reviews have explored the general use of mobile devices for patients with cancer [18][19][20][21][22][23]. Findings from these reviews show that mobile interventions have been developed for a range of purposes, including the prevention, detection, and management of cancer; however, most interventions have been designed...

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“…10 This puts an increasing strain on primary care who play a pivotal role in ensuring patients with suspected cancer receive appropriate referrals. ACE will contribute to the evidence base to inform commissioners and national policy makers about effective approaches to diagnosing patients earlier and, importantly, how to ensure GPs and other healthcare professionals are adequately supported in making decisions about patient care.…”

Section: Streamlining Patient Diagnostic Pathways Via Multidisciplinamentioning

confidence: 99%