Trends in the Prevalence of Overweight and Obesity and Associated Socioeconomic and Household Environmental Factors among Women in Nepal: Findings from the Nepal Demographic and Health Surveys

Rana, Kritika; Ghimire, Puspa Lal; Chimoriya, Romila; Chimoriya, Ritesh

doi:10.20944/preprints202107.0060.v1

Cited by 2 publications

(2 citation statements)

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“…Similar findings were observed in different studies conducted in South Asia,34 USA,48 Ethiopia44 and Nepal 49. Overweight and obesity has been increasing in Nepal particularly among women 50. Obesity being a strong predictor for DM, there is a need to take preventive actions to control obesity which might in turn provide some level of control of growing DM prevalence in the country.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of diabetes mellitus and associated risk factors in Nepal: findings from a nationwide population-based survey

et al. 2022

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ObjectivesThe burden of diabetes mellitus (DM) has increased globally, particularly in low-income and middle-income countries, including Nepal. Population-based nationally representative data on the prevalence of DM is limited. This paper presents the prevalence of DM and its associated risk factors in Nepal.Research designs and methodsThis population-based study sampled 13 200 participants aged 20 years and above in 400 clusters of 72 districts of Nepal. The study used a standardised questionnaire adapted from the WHO STEPwise approach to non-communicable disease risk factor surveillance instrument and digitalised in Android-compatible mobile phones. Fasting and 2 hours postprandial blood samples were taken to test various biochemical parameters. Descriptive followed by multivariate analyses were done to assess the association between explanatory variables and the outcome variable.Primary outcome measuresPrevalence of DM.ResultsThe prevalence of DM was found to be 8.5% (95% CI 7.8% to 9.3%). The odds of DM occurrence were higher in the upper age groups (40–59 years at adjusted OR (AOR) 3.1 (95% CI2.3 to 4.2) and 60+ years at AOR 4.7 (95% CI 3.3 to 6.6)), compared with the group aged 20–39 years. Men were found to have higher odds of DM (AOR 1.3, 95% CI 1.1 to 1.6) compared with women. Urban residents had almost twice higher odds of DM (AOR 1.7, 95% CI 1.4 to 2.2) compared with rural residents. Participants with raised blood pressure (BP) (AOR 2.2, 95% CI 1.8 to 2.7), those who were overweight and obese (AOR 2.0, 95% CI 1.6 to 2.4) and those who had high triglycride level (≥150 mg/dL) (AOR 2.1, 95% CI 1.8 to 2.6) also had twice higher odds of DM compared with those with normal BP, an average body mass index and normal triglyceride level, respectively.ConclusionsTargeted interventions to higher risk groups as well as prevention and control of other associated biological risk factors might help to reduce the prevalence of DM in Nepal.

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Section: Discussionmentioning

confidence: 99%

Prevalence of diabetes mellitus and associated risk factors in Nepal: findings from a nationwide population-based survey

et al. 2022

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“…It is defined as abnormal and excessive fat accumulation that may have serious impacts on health. Obesity and overweight have become increasingly prevalent worldwide [1]. According to the World Population Review in 2022, Nauru (61%) has the highest obesity rate, followed by Cook Islands (55.9%), Palau (55.3%), Marshall Islands (52.9%), and Tuvalu (51.6%).…”

Section: Introductionmentioning

confidence: 99%

Active compounds of fingerroot (Boesenbergia pandurata) for obesity treatment: in silico approaches

Yuniarto

Aji

Ramadhani³

et al. 2022

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Obesity has become increasingly prevalent worldwide each year. Several studies have proven that herbs are effective in preventing obesity. The research delved into the active compounds of Boesenbergia pandurata to reveal their mechanisms of action by utilizing bioinformatics approaches. The research methods included active compounds selection, QSAR analysis, networking analysis, molecular docking, and ADME prediction. The QSAR analysis predicted that the active compounds were correlated with some theoretical activities with more than 0.5 probability, namely vasoprotective, anti-hypercholesterolemic, anti-inflammatory, free radical scavenging, and as a lipid metabolism regulator and TNF expression inhibitor. Furthermore, the results of the networking analysis showed that five compounds (pinocembrin, cardamonin, flavokawain B, flavokawain C, and tectochrysin) had direct interactions with RPS6KB1. Pinocembrin exhibited the highest binding affinityof -7.26 kcal/mol, although not as strong as that of the control ligand (FS9). The ADME prediction indicated that the five compounds were non-toxic and had excellent absorption. It can be concluded that the active compounds of B. pandurata have the ability to improve metabolic syndrome, especially obesity, in silico through several mechanisms, such as suppression of pro-inflammatory cytokine, regulation of lipid metabolism, and those associated with antioxidants.

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Trends in the Prevalence of Overweight and Obesity and Associated Socioeconomic and Household Environmental Factors among Women in Nepal: Findings from the Nepal Demographic and Health Surveys

Cited by 2 publications

References 65 publications

Prevalence of diabetes mellitus and associated risk factors in Nepal: findings from a nationwide population-based survey

Prevalence of diabetes mellitus and associated risk factors in Nepal: findings from a nationwide population-based survey

Active compounds of fingerroot (Boesenbergia pandurata) for obesity treatment: in silico approaches

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