Tribological Study on New Therapeutic Bionic Lubricants

Hua, Zikai; Su, Shihu; Zhang, J. H.

doi:10.1007/s11249-007-9247-4

Cited by 18 publications

(7 citation statements)

References 33 publications

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“…In future work, more studies can be carried out via this newly developed hip joint simulator (HSMS 4203 ). The new lubricants, such as bionic joint fluids (Hua et al, 2007), could be evaluated both for friction and wear under a specified duration, under body-simulated conditions. Moreover, product-level tests for some advanced surface technologies aimed at decreasing friction in hip joints, such as super-lubrication technology (Jiao et al, 2018), could be performed.…”

Section: Discussionmentioning

confidence: 99%

Wear Test Apparatus for Friction and Wear Evaluation Hip Prostheses

et al. 2019

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Wear is a key factor affecting the survivorship of artificial hip joints. Joint wear testers, as called "simulators," are developed to simulate the motions and force of human joints. By using simulators, in vitro wear tests could be performed for artificial joints. This paper introduces a new hip joint simulator developed for the biotribological investigation of artificial hip joints. Friction force measuring module has been set up and assembled to monitor the friction force during the wear tests. Validation tests have been performed using two kinds of wear couples of 28 mm CoCrMo femoral heads, against conventional and X-linked ultra-high molecular weight polyethylene (UHMWPE) acetabular cups. The hip joint simulator is a precise and reliable method, both for the wear evaluation and biotribological investigation of hip prostheses.

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Section: Discussionmentioning

confidence: 99%

Wear Test Apparatus for Friction and Wear Evaluation Hip Prostheses

et al. 2019

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“…In clinical treatment, the most common treatment is injecting the bionic synovial fluid to lubricate the artificial joints . In in vitro wear simulation test, bionic lubricants have been identified as one of the effective factors to improve the lubricating performance of the artificial joints . Hyaluronic acid (HA) is the major components of bionic synovial fluid, which is found to have influences on friction and wear reduction .…”

Section: Introductionmentioning

confidence: 99%

PCEC hydrogel used on sustained‐release hyaluronic acid delivery with lubrication effect

Guo

et al. 2018

J of Applied Polymer Sci

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Injection of bionic synovial fluid (BSF) is a conventional method to improve the lubricity of artificial joints, but BSF cannot maintain long due to the dilution and degradation of BSF in human body. To prolong the effectiveness of hyaluronic acid (HA), which is the major component of BSF, this study applies a temperature-sensitive poly(E-caprolactone)-poly(ethylene glycol)-poly(Ecaprolactone) (PCEC) hydrogel loaded with HA to achieve long-term lubrication. In addition, Fourier transform infrared, nuclear magnetic resonance analysis, X-ray diffraction, scanning electron microscopy (SEM), and gel permeation chromatography spectra were used to analyze the structure of the synthetic hydrogel. Rheological test and test tube inverting method were used to characterize the thermosensitivity. The lubrication properties of the released solution were characterized by UV-vis, tribological tests, SEM, and 3D laser confocal scanning microscope. The experimental results reveal that the triblock PCEC hydrogel contains both hydrophilic block and hydrophobic block, and both PCEC and PCEC/HA hydrogels have phase-changed effect when the temperature increases from room temperature to body temperature. Moreover, the friction coefficient of the released solution from PCEC/HA hydrogel is approximatively 38% lower than that of phosphate buffer saline. And the ability of shear resistance and creep recovery of PCEC/HA hydrogel are better than that of PCEC hydrogel. This study provides an effective approach to achieve long-time lubrication effect for artificial joints.

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“…There are many published papers that discuss possible alternatives to bovine serum [11][12][13][14][15][16][17][18] but the search for an alternative lubricant still continues. It is well understood that any proposed alternative lubricant will need to be safe; produce wear rates and particles that match those produced in the body; and be cost effective with no ethical limitations.…”

Section: Introductionmentioning

confidence: 99%

Potential Synthetic Biolubricant as an Alternative to Bovine Serum

et al. 2016

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Abstract:It is crucial that orthopaedic implant materials are tested in conditions that replicate the natural body's environment as closely as possible. Bovine serum is currently recommended for use by the International Organisation for Standardisation (ISO) for the wear testing of these implant materials, however, the rheological properties of bovine serum do not match fully those of the body's natural lubricant, synovial fluid. This study looks at a potential alternative to bovine serum for the testing of orthopaedic implant materials; 0.5% gellan gum fluid gel. Wear tests using multidirectional motion were conducted on ultra-high molecular weight polyethylene (UHMWPE) pins rubbing against stainless steel plates. Roughness measurements were performed during testing along with particle analysis of the testing lubricant. At two million cycles (equivalent to 121.3 km of sliding), the mean wear factor for the four UHMWPE pins was 0.25 (standard deviation (SD) 0.03) × 10 −6 mm 3 /Nm and there was no evidence of any transfer film on the plate surfaces. The wear factor produced by 0.5% gellan gum fluid gel was lower than that measured in previous studies using bovine serum as the lubricant but greater than the wear factor shown in published work using a similar alternative lubricant (sodium alginate mixed with gellan gum). Work on the development of a suitable alternative lubricant to bovine serum will continue.

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Tribological Study on New Therapeutic Bionic Lubricants

Cited by 18 publications

References 33 publications

Wear Test Apparatus for Friction and Wear Evaluation Hip Prostheses

Wear Test Apparatus for Friction and Wear Evaluation Hip Prostheses

PCEC hydrogel used on sustained‐release hyaluronic acid delivery with lubrication effect

Potential Synthetic Biolubricant as an Alternative to Bovine Serum

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