Trichomonas vaginalis Brain Abscess in a Neonate

Hamilton, H L; Pontiff, Kristen L; Bolton, Michael; Bradbury, Richard S.; Mathison, Blaine A.; Bishop, Henry; Almeida, Marcos de; Ogden, Beverly; Barnett, E. H.; Rastanis, Donna; Klar, Angelle; Uzodi, Adaora S.

doi:10.1093/cid/cix908

Cited by 12 publications

(8 citation statements)

References 14 publications

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“…T. vaginalis infections out of the genitourinary tract are very rare, but a few cases have been described, including a central nervous infection in a premature neonate, leading to death [61].…”

Section: Complicationsmentioning

confidence: 99%

Candidiasis, Bacterial Vaginosis, Trichomoniasis and Other Vaginal Conditions Affecting the Vulva

Vieira‐Baptista

Bornstein

2019

Vulvar Disease

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Section: Complicationsmentioning

confidence: 99%

Candidiasis, Bacterial Vaginosis, Trichomoniasis and Other Vaginal Conditions Affecting the Vulva

Vieira‐Baptista

Bornstein

2019

Vulvar Disease

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“…Symptomatic female patients may undergo discomfort, dysuria, cervicitis, and vaginitis, associated with unusual vaginal discharge with foul-smell and possible infertility [7,8]. In pregnant women, T. vaginalis infection may lead to preterm labor, abnormal infant weight and, if left untreated, the baby is most likely contracts live trichomonas form the infected mother [9]. Considerate investigation of the mechanism of immune response of host to T. vaginalis infection is essential for better understanding the infection strategy, early diagnosis, and treatment of the disease [10].…”

Section: Introductionmentioning

confidence: 99%

Detection of Pro-Inflammatory IL-8 and IL-12 in Iraqi Women Infected with Trichomoniasis

Ali

2021

eijs

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Trichomonas vaginalis is a unicellular flagellated protozoan that resides in female and male genital tract and considered the most prevalent sexually transmitted infectious parasite. The infection rate is relatively equivalent between male and female but trichomoniasis is usually asymptomatic in men. Primary triggering of host inflammatory response to this parasite is not fully understood and most studies address the local reaction of the parasite in female genital tract. In this study, two pro-inflammatory cytokines, IL-8 and IL-12, were investigated in the serum of infected women with Trichomonas vaginalis during acute and chronic stages of the disease. The results demonstrated that the level of IL-8 was significantly higher along the acute and chronic disease stages in female patients. However, the level of IL-12 was significantly increased in the acute group but exceptionally decreased in the chronic group of patients, in comparison with the control group. These results indicate that local infection of the vaginal Trichomoniasis may alter the levels of the studied inflammatory cytokines during infection.

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“…Typically, neonates born to infected mothers are asymptomatic, but may weigh less or experience self-limiting vaginitis with severe vaginal discharge ( 35 ), because the parasite is usually seen in the vaginal areas of neonates (8 and 9). Sometimes, vaginitis in the newborns of mothers with vaginitis caused by T. vaginalis require antimicrobial treatment ( 26 ). Presence of infection in areas other than urogenital area are generally uncommon ( 18 ), but rare cases of the parasite have been reported in other areas such as lungs, cerebrospinal fluid, perinephric abscess, and brain abscess ( 12 , 14 , 26 ).…”

Section: Discussionmentioning

confidence: 99%

Clinical Manifestation and Epidemiological Finding of Trichomonas vaginalis Infection in Unusual Areas of Body in Neonates: A Systematic Review

Taheri¹,

Ghasemikhah²

2022

ijph

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Background: This study intends to increase awareness on the clinical and laboratory diagnosis as well as health care of newborns with trichomoniasis from infected mothers, to introduce this organism as a respiratory pathogen with lower prevalence in other areas, and to outline its manifestations and symptoms. Methods: All case report articles in English language regarding the presence of T. vaginalisin unusual areas among infants, which were available in Scopus, PubMed, Science Direct, Google scholar, and Web of Science published between 1980 and 2021 were searched and reported by two independent researchers. Titles and abstracts of all articles were reviewed for initial screening. Results: After searching the articles and evaluating their quality, 9 full text articles were selected. All reported cases were from 8 different cities (4 countries) in the world. In most cases, the parasite was in the respiratory tract, but it was also reported in the brain and urogenital tract. The most common clinical symptom was respiratory distress. Conclusion: Although the possibility of trichomoniasis infection in unusual areas such as genitals is low, according to the reports collected from around the world, this parasite can also be present outside the genitals. Perhaps, reviewing trichomoniasis along with other diagnoses in these cases may lead to early diagnosis and treatment of the affected neonates.

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Trichomonas vaginalis Brain Abscess in a Neonate

Cited by 12 publications

References 14 publications

Candidiasis, Bacterial Vaginosis, Trichomoniasis and Other Vaginal Conditions Affecting the Vulva

Candidiasis, Bacterial Vaginosis, Trichomoniasis and Other Vaginal Conditions Affecting the Vulva

Detection of Pro-Inflammatory IL-8 and IL-12 in Iraqi Women Infected with Trichomoniasis

Clinical Manifestation and Epidemiological Finding of Trichomonas vaginalis Infection in Unusual Areas of Body in Neonates: A Systematic Review

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