Tricyclic Antidepressants in Chronic Low Back Pain : A Review

Ilmanita, Dzikrina; Hidayati, Hanik Badriyah

doi:10.18860/jip.v4i2.8217

Cited by 5 publications

(4 citation statements)

References 32 publications

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“…Nyeri masih merupakan masalah kesehatan dunia 1,2 . Nyeri merupakan salah satu alasan dan motivasi terkuat bagi pasien untuk mencari pertolongan medis, namun sekaligus merupakan simptom yang kadang terlupakan [3][4][5][6] .…”

Section: Pendahuluanunclassified

Pengaruh Usia dan Jenis Kelamin pada Skala Nyeri Pasien Trigeminal Neuralgia

Hidayati

Amelia

Turchan

et al. 2022

AKSONA : Aksona: Journal of Neurology and Neuroscience

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Pendahuluan: Trigeminal neuralgia (TN) merupakan kondisi yang digambarkan sebagai nyeri hebat seperti tersilet pada satu sisi wajah pada distribusi area saraf ke lima. Nyeri ini dapat mengganggu aktivitas sehari-hari pasien. Rasa nyeri merupakan fenomena subjektif yang dapat dipengaruhi oleh banyak faktor, seperti usia dan jenis kelamin. Tujuan: Mengetahui pengaruh usia dan jenis kelamin terhadap skala nyeri pasien Trigeminal Neuralgia. Metode: Data diambil dari rekam medik pasien pada periode Januari 2017 hingga Juni 2019 di RSUD Dr. Soetomo Surabaya, RS PHC Surabaya, dan RSUD Bangil Pasuruan berdasarkan kriteria inklusi dan eksklusi yang telah ditetapkan. Hasil: TN banyak ditemukan pada kelompok usia 36-64 tahun (55,55%) dan jenis kelamin perempuan (66,67%). Tidak didapatkan hubungan pengaruh usia dan jenis kelamin terhadap skala nyeri pasien (p > 0.05). Kesimpulan: Usia dan jenis kelamin merupakan faktor yang tidak dapat diubah dalam mempengaruhi nyeri. Usia dan jenis kelamin mempengaruhi nyeri melalui perubahan anatomi, hormonal, dan psikologis. Tidak ada hubungan antara usia dan jenis kelamin pada skala nyeri pasien dengan TN.

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Section: Pendahuluanunclassified

Pengaruh Usia dan Jenis Kelamin pada Skala Nyeri Pasien Trigeminal Neuralgia

Hidayati

Amelia

Turchan

et al. 2022

AKSONA : Aksona: Journal of Neurology and Neuroscience

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“…According to a recent review, the use of TCAs in the treatment of low back pain can be successful [ 157 ]. However, the optimal dose of TCAs was not indicated in this study and was determined based on patient tolerance.…”

Section: Treatment Strategies For Neuropathic Painmentioning

confidence: 99%

Diagnosis and Management of Neuropathic Pain in Spine Diseases

Bielewicz

Kamieniak

Szymoniuk

et al. 2023

JCM

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Neuropathic pain is generally defined as a non-physiological pain experience caused by damage to the nervous system. It can occur spontaneously, as a reaction to a given stimulus, or independently of its action, leading to unusual pain sensations usually referred to as firing, burning or throbbing. In the course of spine disorders, pain symptoms commonly occur. According to available epidemiological studies, a neuropathic component of pain is often present in patients with spinal diseases, with a frequency ranging from 36% to 55% of patients. Distinguishing between chronic nociceptive pain and neuropathic pain very often remains a challenge. Consequently, neuropathic pain is often underdiagnosed in patients with spinal diseases. In reference to current guidelines for the treatment of neuropathic pain, gabapentin, serotonin and norepinephrine reuptake inhibitors and tricyclic antidepressants constitute first-line therapeutic agents. However, long-term pharmacologic treatment often leads to developing tolerance and resistance to used medications. Therefore, in recent years, a plethora of therapeutic methods for neuropathic pain have been developed and investigated to improve clinical outcomes. In this review, we briefly summarized current knowledge about the pathophysiology and diagnosis of neuropathic pain. Moreover, we described the most effective treatment approaches for neuropathic pain and discussed their relevance in the treatment of spinal pain.

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“…Combination of analgesic drugs will remarkably lower the adverse effect. 2 Tricyclic and other antidepressant drugs are frequently used as the neuropathic pain therapy, 36 including that of CTS. 37 Amitriptyline gives better results as treatment for sensory symptoms in early CTS.…”

Section: Pharmacological Managementmentioning

confidence: 99%

Current diagnosis and management of carpal tunnel syndrome: A review

Hidayati¹,

Subadi²,

Fidiana³

et al. 2022

Anaesth. pain intensive care

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Carpal tunnel syndrome (CTS) is a condition when median nerve, located in the carpal tunnel, is being suppressed by the surrounding structure. In 1854, the first clinical narration of median nerve compression in a carpal tunnel was found. CTS causes pain, tingling, and weakness in the half ring finger, middle finger, index finger, and thumb. These complaints lead the patients to seek medical help by a visiting doctor. CTS has become the major cause of upper extremity chronic neuropathic pain. CTS affects women 3.6 times more than men. This would cause high costs in medical treatment, rehabilitation, work hours lost compensation, initial pension costs, and new worker training. This makes CTS as a major problem in the field of employment. Carpal tunnel syndrome occurs as a result of chronic repetitive forceful work and other risk factors such as sex, age, heredity, hormonal, and weight. Knowledge of the diagnosis and comprehensive management of CTS are important to the doctor. Recent management based on the newest guidelines are important for clinician knowledge update. Correct diagnosis will lead to appropriate management based on recent CTS guidelines, which in turn will improve the quality of life for patients with CTS. This article will comprehensively discuss the diagnosis and recent management. Abbreviations: CTS - Carpal tunnel syndrome; NHIS - National Health Interview Study; EDX - Electrodiagnostic studies; SCT - Scratch Collapse Test; CSA - Cross-sectional area; PRP - Platelet-rich plasma; LLLT - Low-Level Laser Therapy; US – Ultrasound; DN - Dry needling; ECTR - Endoscopic carpal tunnel release; PDI - perineural dextrose injection; BCTQ - Boston Carpal Tunnel Questionnaire Key word: Carpal tunnel syndrome (CTS); neuropathy; pain; numbness; safe working environment; human; disease Citation: Hidayati HB, Subadi I, Fidiana, Puspamaniar VA. Current diagnosis and management of carpal tunnel syndrome: A review. Anaesth. pain intensive care 2022;26(3):394-404. DOI: 10.35975/apic.v26i3.1902 Received: August 16, 2021; Reviewed: April 24, 2022; Accepted: April 28, 2022

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Tricyclic Antidepressants in Chronic Low Back Pain : A Review

Cited by 5 publications

References 32 publications

Pengaruh Usia dan Jenis Kelamin pada Skala Nyeri Pasien Trigeminal Neuralgia

Pengaruh Usia dan Jenis Kelamin pada Skala Nyeri Pasien Trigeminal Neuralgia

Diagnosis and Management of Neuropathic Pain in Spine Diseases

Current diagnosis and management of carpal tunnel syndrome: A review

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