Triketone-terpene meroterpenoids from the leaves of Rhodomyrtus tomentosa

Deng, Xin; Wang, Xiurong; Wu, Lin

doi:10.1016/j.fitote.2020.104585

Cited by 6 publications

(1 citation statement)

References 18 publications

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“…As a part of our investigation on bioactive compounds from natural sources [ 11 , 12 , 13 ], phytochemical investigation on this species was conducted. As a result, two new benzophenone glycosides ( 1 and 2 ), along with four known compounds ( 3 – 6 ), were isolated and characterized from H. seniawinii .…”

Section: Introductionmentioning

confidence: 99%

Benzophenone Rhamnosides and Chromones from Hypericum seniawinii Maxim.

Xia

Hu²,

Qian³

et al. 2022

Molecules

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Two new benzophenone glycosides, hypersens A and B, along with four known compounds, (S)-(+)-5,7-dihydroxy-2-(1-methylpropyl) chromone (3), 5,7-dihydroxy-2-isopropylchromone (4), urachromone B (5), and 3-8′′ bisapigenin (6), were isolated from Hypericum seniawinii. The structures of new compounds (1 and 2) were elucidated according to comprehensive spectroscopic data analyses. The absolute configurations of 1 and 2 were determined by electronic circular dichroism (ECD) calculations. All isolated compounds were evaluated for their neuroprotective effect using corticosterone-induced PC12 cell injury. In addition, compounds 1–6 were evaluated for their anti-inflammatory activity in lipopolysaccharide-induced RAW 264.7 cells. Compound 6 was a biflavonoid and significantly inhibited the production of nitric oxide with an IC50 value of 11.48 ± 1.23 μM.

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Section: Introductionmentioning

confidence: 99%