Triterpene glycosides from Astragalus icmadophilus

Evaluation of the immunomodulatory properties in mice and in vitro anti-inflammatory activity of cycloartane type saponins from Astragalus species

“…is represented by 445 species, of which 224 are endemic, in the flora of Turkey (Aytaç , 2000). Previous investigations of Turkish Astragalus species give rise to the isolation of about 70 cycloartane-type saponins including five different aglycones (Bedir et al, 2000a(Bedir et al, ,b, 2001aPolat et al, 2009Polat et al, , 2010Horo et al, 2010;Gülcemal et al, 2011). Besides, our current studies on biological activity of Astragalus saponins related to the traditional use of the Astragalus roots in South East Anatolia to cure leukemia showed that the anti-leukemia activity might be due to the stimulation of the immune system.…”

In vitro growth stimulatory and in vivo wound healing studies on cycloartane-type saponins of Astragalus genus

“…Our earlier investigations of Turkish Astragalus species resulted in the isolation of over sixty cycloartane glycosides including five different aglycones (Bedir et al, 1998a(Bedir et al, ,b, 1999a(Bedir et al, ,b, 2001aPolat et al, 2009Polat et al, , 2010Horo et al, 2010).…”

Seven new dammarane triterpenes from the floral spikes of Betula platyphylla var. japonica

“…Regarding 24-hydroxy-20,25-epoxy-dammaranes in the literature, 24(R*)-hydroxy-20(S*),25-epoxy and 24(S*)-hydroxy-20(R*),25-epoxydammaranes have been reported with complete NMR data [13][14][15][16]. In contrast, the 1 H and 13 C NMR data of 24(S)-hydroxy-20(S),25-epoxydammarane reported previously [17] were found to be exactly identical to those of well-studied 20,24-epoxydammaranes [18] in the course of our structure elucidation of compounds 6 and 7.…”