Triterpenes and fatty acids from Nepeta aragonensis

Carstenn-Lichterfelde, C. von; Rodrı́guez, Benjamı́n; Valverde, Serafı́n

doi:10.1016/0031-9422(73)80529-1

Cited by 16 publications

(7 citation statements)

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“…Nine natural diterpenoid compounds (1,2,4,7,8,II,12,13,and 14) isolated from Sideritis pusilla (Lange) Pau subsp. and five semisynthetic diterpenoid compounds (3, 5, 6, 9, and 10) obtained from 2, were tested for antimicrobial activity against a range of microorganisms.…”

Section: Resultsmentioning

confidence: 99%

Studies on the Relationship of Structure to Antimicrobial Properties of Diterpenoid Compounds fromSideritis

Diaz¹,

Garcı́a-Granados²,

Moreno³

et al. 1988

Planta Med

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As a result of a study of antimicrobial agents from Spanish Sideritis species, we now report a series of natural and semisynthetic diterpenoid compounds with selective antimicrobial activity toward Gram-positive bacteria and, in some cases, also toward yeasts. A 1,3diolic group is responsible for this activity. Another hydroxyl group on the molecule produces a drastic decrease in antimicrobial activity. On the other hand, an acetoxyl group increases the inhibitory action. To the best of our knowledge, 1-acetyljativatriol (2) is the first natural entbeyerenic diterpenoid which has been proved to show antimicrobial activity.

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Section: Resultsmentioning

confidence: 99%

Studies on the Relationship of Structure to Antimicrobial Properties of Diterpenoid Compounds fromSideritis

Diaz¹,

Garcı́a-Granados²,

Moreno³

et al. 1988

Planta Med

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“…Isolation of Ursolic Acid and Its Reduction to Uvaol. Uvaol, a ursane-type dihydroxy triterpenoid, is present in various plants such as Plumeria rubra, 43 Olea europaea, 44 Nerium oleander, 45 Lavandula pedunculta, 46 and Malus domestica. 47 One-step conversion of ursolic acid, a 6-6-6-6-6 pentacyclic triterpenic acid having an identical triterpenoid backbone, to uvaol has also been reported.…”

Section: Resultsmentioning

confidence: 99%

Garland, Flower, and Petals via a Hierarchical Self-Assembly of Ursane-Type Triterpenoid Uvaol

Ghorai

Bag

2021

ACS Omega

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Uvaol, a 6-6-6-6-6 pentacyclic dihydroxy ursane-type triterpenoid, is isolable from different parts of plants Plumeria rubra, Olea europaea, Nerium oleander, Lavandula pedunculta, and Malus domestica. It is also obtained by a one-step reduction of naturally occurring triterpenoid ursolic acid. Herein, we report the first self-assembly properties of uvaol in different neat organic liquids and aqueous organic binary liquid mixtures. Spontaneous self-assembly of uvaol in different neat liquids and binary liquid mixtures yielded garland, flower, and petal-like porous superstructures of nano- to micrometer dimensions. Utilization of self-assemblies has been demonstrated in generation of anticancer drug conjugates and the removal of carcinogenic and toxic chemicals.

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“…The relative stereochemistry of 1 was determined by comparison of the spectral data of 1 with those recorded for other known clerodane diterpenoides [6,7,10] as well as from the NOE spectrum. The CH 3 -19 showed NOE correlation with H-3, H-4, and H-6, whereas CH 3 -17 showed similar correlation with H-6.…”

Section: Resultsmentioning

confidence: 99%

Nepetanal and nepetanoate: a new diterpene aldehyde and a benzene derivative ester from Nepeta juncea

Hussain

Jamila

Khan

et al. 2009

Magnetic Reson in Chemistry

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Triterpenes and fatty acids from Nepeta aragonensis

Cited by 16 publications

References 1 publication

Studies on the Relationship of Structure to Antimicrobial Properties of Diterpenoid Compounds fromSideritis

Studies on the Relationship of Structure to Antimicrobial Properties of Diterpenoid Compounds fromSideritis

Garland, Flower, and Petals via a Hierarchical Self-Assembly of Ursane-Type Triterpenoid Uvaol

Nepetanal and nepetanoate: a new diterpene aldehyde and a benzene derivative ester from Nepeta juncea

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