Triterpenoids

Connolly, Joseph D.; Hill, Robert A.

doi:10.1039/np9860300421

Cited by 19 publications

(3 citation statements)

References 86 publications

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“…Since 1985, Connolly and Hill have regularly reviewed the scientific literature dealing with triterpenoid characterization from natural resources. [239][240][241][242][243][244][245][246][247][248][249][250][251][252][253][254][255][256] Although numerous triterpenoids possessing various scaffolds have been reported, only a small portion of them were explored systematically for their pharmacological activities. Of those so explored, most showed only marginal potency in preliminary screening.…”

Section: Discussionmentioning

confidence: 99%

Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents

et al. 2009

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Section: Discussionmentioning

confidence: 99%

Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents

et al. 2009

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“…These highly oxygenated compounds also display a somewhat unusual oxidation pattern in ring A which has been seen in 3-hydroxyfriedel-3-en-2-one, isolated from the bark of Quercus suber and in 3-hydroxy-2-oxofriedel-3-en-29-oic acid . The remaining oxygen functions, such as the C18−C30 lactone and the acetates, benzoates, or tiglate groups at various positions, have been individually reported previously, but not in combination 6 Mean larval weights of the European corn borer exposed to 50 ppm of spirocaraclitones in diet. …”

Section: Possible Biogenetic Pathways To the Spirocaracolitone Ring S...mentioning

confidence: 73%

Spirocaracolitones, CD-Spiro Triterpenoids from Ruptiliocarpon caracolito

et al. 1997

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Six CD-spiro-triterpenoids have been isolated and identified from the methylene chloride soluble extracts of the bark of Ruptiliocarpon caracolito. The structures of these compounds, named spirocaracolitones A−F, were determined by a combination of X-ray and high field NMR studies. The spirocaracolitones represent the first examples of a class of triterpenes which have a spiro system connecting rings C and D; they also carry an unusual 12-α-methyl group. It is postulated that these compounds are derived biogenetically from a friedelin derivative. Initial biological screening revealed up to 80% decreases in the rate of growth of the larvae of the European corn borer when these compounds were administered at the rate of 50 ppm in the diet.

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“…Without them, plant terpenoids with a lupane skeleton, lupeol is the simplest one and recently has been reported as the active principle of Crataeva religiosa when it was tested on the habitual models of inflammatory response, it showed moderate activity on the carrageenan-induced rat hind paw and rat pleurisy [33].…”

Section: Resultsmentioning

confidence: 99%

Anti-inflammatory effects of medicinal plants mixture used by Bedouin people in Saudi Arabia

Elsharkawy

Elshathely

Jaleel³

et al. 2013

Herba Polonica

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S u m m a r y Due to toxic and adverse side effects of synthetic drugs, traditional herbal medicine has the potential as a source of new bioactive molecules. That is why we investigated this research, searching new anti-inflammatory drugs from plants growing around us. The anti-inflammatory effect of the mixture of different plants used in traditional medicine (Alkanna tinctoria, Rubia tinctorum and Artemisia herba alba) were studied using carrageenan-induced paw edema (oil mixture extract 100 mg/kg and 200 mg/kg). These material reduces carrageenan-induced inflammation in rats and shows inhibition after 4 h especially at a concentration 200 mg/ EXPERIMENTAL PAPER Unauthenticated Download Date | 10/8/15 6:41 AM 77 Anti-inflammatory effects of medicinal plants mixture used by Bedouin people in Saudi Arabia Vol. 59 No. 3 2013kg. Oil mixture extract were investigated by capillary GC and GC-MS in combination with retention indices revealed the presence of about 17 compounds: artemisol, epiglobulol and α-bisabolol are the main constituents as well as volatile oil and other triterpenes: taraxasterol, stigmasterol, ursan-12-ene, olean-12-ene, betulin, germincol, lupeol acetate and lupeol. Other heterocyclic compounds: moropholine and piperidinol were also identified.

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Triterpenoids

Cited by 19 publications

References 86 publications

Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents

Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents

Spirocaracolitones, CD-Spiro Triterpenoids from Ruptiliocarpon caracolito

Anti-inflammatory effects of medicinal plants mixture used by Bedouin people in Saudi Arabia

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