Tritium in Rabbits after Ingestion of Freeze-Dried Tritiated Food and Tritiated Water

Pietrzak-Flis, Z.; Radwan, I.; Indeka, L.

doi:10.2307/3574790

Cited by 28 publications

(9 citation statements)

References 10 publications

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“…For example, tritium incorporation into tissues of rats, rabbits, pigs, and calves exposed for an extended period to OBT in food was generally 4-10 times higher than after similar exposure to tritiated water (Kirchmann et al 1977;Rochalska and Szot 1977;Pietrzak-Flis et al, 1978;. Etnier et al (1984) concluded from a review of biokinetic data for tritium that intake of OBT in food could result in absorbed doses up to about five times higher than intake of tritiated water.…”

Section: Organically Bound 3 H (Obt)mentioning

confidence: 99%

Uncertainties in Cancer Risk Coefficients for Environmental Exposure to Radionuclides. An Uncertainty Analysis for Risk Coefficients Reported in Federal Guidance Report No. 13

Pawel¹,

Leggett²,

Eckerman³

et al. 2007

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Section: Organically Bound 3 H (Obt)mentioning

confidence: 99%

Uncertainties in Cancer Risk Coefficients for Environmental Exposure to Radionuclides. An Uncertainty Analysis for Risk Coefficients Reported in Federal Guidance Report No. 13

Pawel¹,

Leggett²,

Eckerman³

et al. 2007

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“…The incorporation of tritium after chronic exposure to tritiated water and food has been extensively studied [4,10,13,17,19,22], while biological effects of tritium irradiation were studied mainly using tritiated water. The effect of tritiated food was examined only in a few works [18,20,21].…”

Section: Discussionmentioning

confidence: 99%

Effect of lifetime intake of organically bound tritium and tritiated water on the oocytes of rats

Pietrzak-Flis

Wasilewska-Gomułka

1984

Radiat Environ Biophys

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Rats were continuously exposed to constant activity of tritium in drinking water (HTO group) or to tritium organically bound in food (T-food group) in the period from conception of F1 generation through maturity. Female offspring were killed at the age of 21 and 71 days and the oocytes in their ovaries were counted. Mean dose rates absorbed in the ovaries were for the HTO groups 7.25 +/- 0.37 and 14.73 +/- 0.79 mGy/day and for the T-food group 4.84 +/- 0.25 mGy/day. Reduction in the oocyte number in the ovaries of females exposed to tritiated food was bigger than in the ovaries of females exposed to tritiated water. The dependence of the survival of small oocytes on the dose rate and the corresponding total accumulated dose had an exponential character. The damaging effect of tritium was for the period from conception to 21 days of age bigger than from 21 to 71 days of age. Of all stages of oocyte development, the highest sensitivity to tritium irradiation was observed in small oocytes and oocytes with one complete layer of follicle cells. As a result, relative number of growing and large oocytes increased.

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“…An example is listed in Table 4, where the distribution of tritium in organic fractions of various pig organs following administration of tritiated water, tritiated milk powder, and tritiated potatoes is compared. In a recent publication, feeding of tritiated alfalfa to rabbits was reported to yield 2-9 times higher specific activities of non-exchangeable hydrogen than after consumption of the same activity given as tritiated water [68]. In a recent publication, feeding of tritiated alfalfa to rabbits was reported to yield 2-9 times higher specific activities of non-exchangeable hydrogen than after consumption of the same activity given as tritiated water [68].…”

Section: Tritium In the Biospherementioning

confidence: 99%

Radiation problems in fusion energy production

Feinendegen

Cronkite

Bond

1980

Radiat Environ Biophys

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Radiation research and biology is confronted today with an armada of questions, anxieties and fears posed by a multitude of different population groups, by the concerned ordinary citizen, by technologists and engineers, by politicians and managers, and, of course, by our own colleagues in science. There is an urgent challenge for providing new energy resources. Challenges always create divers opinions and the more urgent a challenge, the more emotional becomes the dialogue.The present issues of controversy will be intensified as the fusion reactor technology approaches the door step of publicity and the possible health detriment from its radioactive emissions arouse concern.In this paper the inventory of radionuclides in a model fusion reactor will be reviewed. Tritium is the major constituent to be concerned with [31,60,69]. The question of tritium releases and pathways to man will be covered. Next pertinent questions related to the absorbed dose from incorporated tritium and late effects will be analyzed. In this context the problem of defining the radiation-sensitive site in the body for incorporated tritium and the RBE of the beta particle appears controversial and is crucial. Radionuclide Inventory in the Fusion ReactorThe present concept of the fusion reactor is based on the D-T fusion producing 3.5 MeV alpha-particles and 14 MeV neutrons for both, heat generation and tritium breeding. The blanket around the fusion chamber thus serves as shield and for cooling. Since it contains lithium in various chemical forms [31] tritium breeding is permanent. Figure 1 gives a schematic representation of a fusion reactor. The neutrons and tritium, shown in black, are sources of radiation problems. The neutrons are

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Tritium in Rabbits after Ingestion of Freeze-Dried Tritiated Food and Tritiated Water

Cited by 28 publications

References 10 publications

Uncertainties in Cancer Risk Coefficients for Environmental Exposure to Radionuclides. An Uncertainty Analysis for Risk Coefficients Reported in Federal Guidance Report No. 13

Uncertainties in Cancer Risk Coefficients for Environmental Exposure to Radionuclides. An Uncertainty Analysis for Risk Coefficients Reported in Federal Guidance Report No. 13

Effect of lifetime intake of organically bound tritium and tritiated water on the oocytes of rats

Radiation problems in fusion energy production

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