Tualang honey induces apoptosis and disrupts the mitochondrial membrane potential of human breast and cervical cancer cell lines

Gelam and Nenas Honeys Inhibit Proliferation of HT 29 Colon Cancer Cells by Inducing DNA Damage and Apoptosis while Suppressing Inflammation

“…Jaganathan and Mandal, 2009 b also demonstrated similar findings on Indian honeys. Tualang honey which consisted of high flavonoids, phenolic acid and hydroxymethylfurfural was also reported to cause apoptosis of breast and cervical cancer cells (Fauzi et al, 2011). A bioactive compound extracted from honey such as eugenol showed increased apoptosis of colon cancer cells by arresting cell cycle at sub-G1 phase and activation of p53 and caspase-3 (Jaganathan et al, 2010).…”

Gelam Honey and Ginger Potentiate the Anti Cancer Effect of 5-FU against HCT 116 Colorectal Cancer Cells

“…Honey was also known to exert anti-cancer effects in several types of cancer cells including colon cancer Fukuda et al, 2011). Malaysian local honey especially Tualang honey has been found to induce anti-proliferative effects on cervical and breast cancer cell lines (Mohamed et al, 2010) as well as anti-bacterial activity against Acinetobacter baumanni (Fauzi et al, 2011). Likewise, another local honey, Gelam honey has been shown to inhibit the growth of colon cancer cell line namely HT 29 (Wen et al, 2012).…”

Phytochemical screening and antimicrobial activity of apiary honey produced by honey bee (Apis mellifera) on clinical strains of Staphylococcus aureus, Escherichia coli and Candida albicans

“…In the modern era, the different biological, chemical and physical properties of honey have revealed several beneficial claims through different techniques. The multi facet properties of honey anchored in the scientific world is regarded as a sweetener, functional food, antioxidant, antimicrobial, antiseptic, prebiotics, probiotics, immunomodulatory, antiinflammatory, anti-tumor and anti-cancer effect amongst others (Jenkins et al, 2011;Conway et al, 2010;Fauzi et al, 2011). Above and beyond its therapeutic effects or medicinal attributes (Mohapatra et al, 2011;Conti et al, 2007), it is also of potential use as bio-indicators for environmental contamination (Celechovska and Vorlova, 2001).…”