Tubercles of the Choroid

Illingworth, R. S.; Lorber, John

doi:10.1136/adc.31.160.467

Cited by 29 publications

(6 citation statements)

References 4 publications

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“…Choroidal tubercles can be seen in up to 38.4% of miliary and meningeal tuberculosis cases. [ 2 ] The morphology of the choroidal lesions seen in our case was typical of choroidal tubercles. We observed neovascularization over some choroidal tubercles; these regressed along with the overlying neovascularization following treatment.…”

Section: Discussionmentioning

confidence: 71%

Successful management of proliferative diabetic retinopathy and multiple choroidal tubercles in a patient with miliary tuberculosis

Chawla¹,

Venkatesh²,

Tripathy³

et al. 2018

J Ophthalmic Vis Res

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Section: Discussionmentioning

confidence: 71%

Successful management of proliferative diabetic retinopathy and multiple choroidal tubercles in a patient with miliary tuberculosis

Chawla¹,

Venkatesh²,

Tripathy³

et al. 2018

J Ophthalmic Vis Res

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“…Multifocal choroidal tubercles are the most characteristic clinical feature of MTB and provide evidence that intraocular tuberculosis develop from hematogenous spread of tubercular bacilli from pulmonary or other sites. [4][5][6][7] The tubercles may be unilateral or bilateral, greyish white or yellowish in colour, discrete with indistinct border lying deep in the choroid and 0.5 mm to 3 mm in diameter. Usually they are multiple and less than 5 in number and may be accompanied by hemorrhage or overlying serous detachment.…”

Section: Discussionmentioning

confidence: 99%

Fundus Changes in Milliary Tuberculosis: A Retrospective Cohort Study

Jain¹

2019

Delhi Journal of Ophthalmology

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Introduction: Milliary tuberculosis occurs due to haematogenous spread of infection. It is assumed that intraocular tuberculosis is spread hematogenously from primary infection to elsewhere. The choroidal tubercles may be one of the earliest signs of milliary disease and is probably the most common form of ocular tuberculosis.Methods: This is a retrospective observational single site study of 113 patients with milliary tuberculosis from 2001 to 2015. Fundus examination was done after full dilatation of the pupil with direct and indirect ophthalmoscope. The diagnosis of intraocular tuberculosis was presumed to be based on suggestive ocular lesion in context of evidence of systemic infection and response to antitubercular treatment.Results: There were 77 females (68%) and 36 (32%) males. The commonest age group was 21 to 40 years as 67 (59.3%) patients belonged to this productive age group. Eighty eight (77.9%) patients were from rural areas. Fundus changes were present in 14 patients (12.39%) and these were choroidal tubercles (8.8%), papillitis (4.4%), macular edema (0.9%) and vitritis (0.9%). Choroidal tubercles were present in 10 patients. Among these, two had associated papillitis and one also had vitritis. Three patients had only papillitis and in another one, only macular edema was present. Papillitis was present in five patients in our study. HIV did not increase the incidence of ocular lesions. Conclusion:The most common fundus changes were choroidal tubercles and optic neuropathy in our series. Early detection of these choroidal tubercles may be helpful in diagnosis as well as in treatment. The optic nerve may be involved not only by the toxic effect of anti-tubercular drug but also in the disease process itself.

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“…Published literature has described the healing of tubercles as either a process of complete resolution or alternatively scar formation [ 1 , 2 ]. The latter process consists of increasingly distinct borders with increasing marginal pigmentation and resulting in the formation of a white scar.…”

Section: Discussionmentioning

confidence: 99%

Healing patterns of choroidal tubercles after antitubercular therapy

Mehta

2011

J Ophthal Inflamm Infect

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A 28-year-old female patient with disseminated tuberculosis and choroidal tubercles on a regimen of systemic antitubercular therapy underwent fundus photography and optical coherence tomography (OCT). This was carried out monthly until complete healing of the tubercle was seen. The tubercle consisted of a central white-yellow core, consistent with choroiditis, with a faint hyperpigmentation surrounding it. There was a surrounding diffuse rim of inflammation. By the second month, the hyperpigmented rim was more prominent as were the outer edges of both the central core and the outer rim. Over time, the outer rim had largely faded with concurrent scar formation in the core. The initial OCT analysis revealed a raised RPE-choriocapillaris complex. With healing, there was a marked reduction in the choroidal lesional height suggesting resolution.

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Tubercles of the Choroid

Cited by 29 publications

References 4 publications

Successful management of proliferative diabetic retinopathy and multiple choroidal tubercles in a patient with miliary tuberculosis

Successful management of proliferative diabetic retinopathy and multiple choroidal tubercles in a patient with miliary tuberculosis

Fundus Changes in Milliary Tuberculosis: A Retrospective Cohort Study

Healing patterns of choroidal tubercles after antitubercular therapy

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