Tuberculosis in Sudan: Efficiency of diagnostic techniques commonly used and investigation of some sociodemographic factors which may influence the disease prevalence

Sirelkhatim, Mohammed; Eldin, Ghada S. Sharaf; Almula, Imad Fadl; Babiker, Ahmed; Omer, Rihab Ali

doi:10.4103/1858-5000.189559

Cited by 4 publications

(3 citation statements)

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“…A., 2012 [ 21 ] 2012 Cross sectional Kassala Suspected TB patients Prevalence & Risk factors 2,778 Female Not determined Ali, A. 2016 [ 22 ] 2016 Case control Khartoum TB patients Risk factors 315 Both Mean 33 years Aman, 2017 [ 23 ] 2017 Case control Gezira TB patients’ contacts Prevalence (Bacteriological and radiological methods) 657 Both Mean 33 years Awadalla, 2010 [ 24 ] 2010 Case control Khartoum HIV/AIDS patients Prevalence 291 Both Mean 36 years Banaga, 2016 [ 25 ] 2016 Cross sectional khartoum hemodialysis patients Prevalence & Risk factors 1,328 Both Mean 36 years Bottieau, 2022 [ 26 ] 2022 Cross sectional Gadarif Febrile patients Prevalence (Bacteriological and Nuclic acid methods) 667 Both Media 35 years ...…”

Section: Resultsmentioning

confidence: 99%

Tuberculosis in Sudan: systematic review and meta analysis

Badawi,

SalahEldin,

Idris

et al. 2024

BMC Pulm Med

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Every year, 10 million people fall ill with tuberculosis (TB). Despite being a preventable and curable disease, 1.5 million people die from TB each year -making it the world’s top infectious disease. TB is the leading cause of death of people with HIV and also a major contributor to antimicrobial resistance. Its presumed that TB was the cause of 1% of the total deaths among inpatients in Sudan in 2017. The current study is aimed to provide pooled prevalence of Mycobacterium tuberculosis among Sudanese as well as to determine any socio-cultural risk factors associated. A systematic review of the literature was conducted and regulated in accordance with the PRISMA Statement. After abstract and full text screening only twenty-six articles met our inclusion criteria and passed the quality assessment procedure. Pulmonary tuberculosis prevalence was assessed in sixteen included studies among participants from Khartoum, Gezira, Kassala, Blue Nile, River Nile, White Nile, Gadarif, Red sea, North Kordofan, Northern State, Sennar and West Darfur States, representing a total sample size of 11,253 participants of suspected individuals such as febrile outpatients, TB patients’ contacts and other groups such as HIV/AIDS patients, hemodialysis patients, School adolescents as well as pregnant women. The pooled prevalence was 30.72% [CI: 30.64, 30.81]. Moreover, Khartoum State recorded the highest pooled prevalence as 41.86% [CI: 14.69, 69.02] based on a total sample size of 2,737 participants. Furthermore, male gender and rural residence were found to be significantly associated with TB infection. Further research with larger sample sizes targeting prevalence and risk factors of TB among Sudanese population is needed to be conducted.

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Section: Resultsmentioning

confidence: 99%

Tuberculosis in Sudan: systematic review and meta analysis

Badawi,

SalahEldin,

Idris

et al. 2024

BMC Pulm Med

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“…Moreover, 10-99 AFB/100 were recorded as 1+, 1-10 AFB/field recorded as 2+, and more than 10 AFB/field after examining at least 20 fields was recorded as 3+. 8 All negative smears were rechecked.…”

Section: Ziehl-neelsen Smear and Microscopymentioning

confidence: 99%

Untitled

2020

JMEN

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Background: Tuberculosis (TB) is a bacterial disease that can be spread through the air. It usually attacks the lungs, but it can also affect and damage the other parts of the body such as the brain, kidneys, or spine. Globally, the disease remains to be a major health problem in countries suffering from poverty and unsettlement like Sudan. Our study aimed to evaluate the prevalence of pulmonary TB and the value of the socio-demographic characteristic of patients and laboratory findings in the assessment of tuberculosis infection. Methods: During the period from May 2017 to December 2018, 1434 subjects were included. M.tuberculosis infection was examined using Ziehl-Neelsen (ZN) stain and GeneXpert test, and Human immunodeficiency virus infection was checked by the immuno-chromatographic test. Results: Out of 1434 participants, 795 (55.4%) were males and 639 (44.6%) were females as well as 670 (46.7%) were suffering from infection relapse. The percentage of HIV infection, MTB detection, and RF resistance among the study contributors was 1.4%, 16.5%, and 15.5%, respectively. Infection relapse was more in females than males. Among the medically suspected new participants (449), the overall reported prevalence for pulmonary TB was 15.8% based on the Gene Xpert test. Furthermore, the percentage of RF resistance was lower in females than males and participants age 1-20 years compared to 21-40, 41-60, and 61-80 age groups. There was a significant difference in the microscopy findings among disease history, bacillary levels and RF susceptibility patterns, P-values less than 0.05. Moreover, the odd of detection of a high bacillary level was significantly less likely in females than males. Whereas, it is higher in case of treatment failure and infection with RF resistant strain, P-values less than 0.05. Conclusions: The findings of the current study were illustrated the current prevalence of pulmonary TB and shown the value of socio-demographic features and laboratory findings in the assessment of pulmonary tuberculosis infection.

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“…In Sudan, civil war in certain areas and people’s displacement while searching for a better life are among the various factors currently faced by Sudan, which may lead to the increase in the occurrence and spread of many health hazardous diseases, among them are TB infection and TB treatment adherence [ 10 ]. Sudan has adopted the DOTS strategy since 1993.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of education intervention of tuberculosis treatment adherence in Khartoum State: A study protocol for a randomized control trial

et al. 2022

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Background Treatment failure and disease relapse among tuberculosis (TB) patients are commonly caused by non-adherence. It can lead to prolonged infection, increased transmission, drug resistance, and loss of life. Even though the causative microorganism of TB has been identified for more than a century, the disease is still a substantial public health problem worldwide. This research aims to devise, implement, and assess an educational intervention to improve adherence to TB treatment. Methods and findings A randomised clinical trial involving 146 Sudanese TB patients will be conducted at the Abu Anga hospital in Khartoum. The participants will be randomly assigned to the intervention and control groups. A 2-hour session will be offered to the intervention group in a one-day TB educational intervention course. The same educational materials will also be provided to the control group after the randomised controlled trial (RCT). Data will be collected at baseline, one month, and four months after the intervention. The primary outcome of interest is TB treatment adherence, while secondary outcomes include quality of life score, tuberculosis knowledge, and health belief domains. Generalised estimating equations (GEE) in SPSS software version 25.0 will be utilised to evaluate the changes over time. Conclusions This trial will provide information that could be used in improving TB control strategies to achieve better results in the adherence of healthcare services to the norms of the National Program and patient adherence to the disease treatment and cure. Trial registration This study is registered at TCTR: (TCTR20210607006).

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Tuberculosis in Sudan: Efficiency of diagnostic techniques commonly used and investigation of some sociodemographic factors which may influence the disease prevalence

Cited by 4 publications

References 0 publications

Tuberculosis in Sudan: systematic review and meta analysis

Tuberculosis in Sudan: systematic review and meta analysis

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Effectiveness of education intervention of tuberculosis treatment adherence in Khartoum State: A study protocol for a randomized control trial

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