Tuberculosis of the middle ear: A systematic review

Pai, Kavya; Omiunu, Ariel O.; Peddu, Dhiraj; Au, Vivienne H.; Baredes, Soly; Jyung, Robert W.; Eloy, Jean Anderson; Fang, Christina H.

doi:10.1016/j.amjoto.2022.103571

Cited by 8 publications

(5 citation statements)

References 63 publications

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“…La parálisis facial permanente se dio en un porcentaje inferior (n=3; 6,98%) pero no despreciable debido a la gravedad del mismo. La probabilidad de sufrir estas consecuencias parece estar estrechamente relacionada con el tiempo hasta el diagnóstico y la instauración de un tratamiento adecuado [ 4 ].…”

Section: Discussionunclassified

“…siempre resultados negativos, y no se solicitó estudio de micobacterias hasta que se tomaron muestras por mastoidectomía. Los hallazgos histopatológicos más comunes son necrosis caseosa, material inflamatorio con células epitelioides y células gigantes de Langerhans [4]. Esto en el contexto clínico adecuado puede ser suficiente para justificar el inicio del tratamiento antituberculoso, sin embargo, es importante el envío de las muestras al laboratorio de microbiología para que así se realice la confirmación y los estudios de sensibilidad correspondientes.…”

Section: Presentación Del Casounclassified

“…En los países desarrollados, la otitis media tuberculosa (OMT) es una afectación rara que representa entre el 0,05% y 0,9% de los casos de infección crónica de oído medio [ 3 ]. La patogénesis de la OMT implica tres mecanismos principales: la diseminación hemática desde otros focos, principalmente pulmonar u otros órganos distantes, la propagación por contigüidad a través de la trompa de Eustaquio o la implantación directa a través del conducto auditivo externo por perforación timpánica [ 4 ]. La presentación clínica se caracteriza por la triada clásica de otorrea no dolorosa de larga duración, múltiples perforaciones timpánicas y en algunos casos parálisis facial.…”

Section: Introductionunclassified

“…Estos síntomas poco específicos, pueden confundirse fácilmente con otras causas más comunes de otitis crónica, llevando a retrasos en el diagnóstico y tratamiento [ 4 ].…”

Section: Introductionunclassified

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Tuberculous otitis media: A case presentation and review of european literature

Aguilera-Franco,

Franco-Acosta,

Yépez-Naranjo

et al. 2023

Rev Esp Quimioter

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Tuberculous otitis media (TOM) is a rare affectation in our environment that represents a challenge in its diagnosis due to the non-specific symptoms that it usually presents. This paper presents our experience in the diagnosis of a case of TOM in a 66-year-old woman with hearing loss and chronic otorrhea of more than 6 months of evolution that did not respond to conventional treatments. In addition, a review of the cases published in the last 20 years (2000-2022) in countries of the European Union (EU) is carried out. The most common symptoms were otorrhea (n=43; 100%), hearing loss (n=37; 86.05%), eardrum perforation (n=19; 44.18%), facial paralysis (n=12, 27,91%) and ear pain (n=13; 30,23%). The most used sample for diagnosis was the biopsy obtained by mastoidectomy (n=34; 79.06%). All patients were given antituberculous therapy for a mean duration of 8.11 months (range, 6-12 months). The most frequent aftereffect was hearing loss (n=28; 65.12%). TOM should be included in the differential diagnosis of chronic suppurative otitis, since early diagnosis and treatment reduce the probability of suffering irreversible sequelae.

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Section: Discussionunclassified

Section: Presentación Del Casounclassified

Section: Introductionunclassified

“…Estos síntomas poco específicos, pueden confundirse fácilmente con otras causas más comunes de otitis crónica, llevando a retrasos en el diagnóstico y tratamiento [ 4 ].…”

Section: Introductionunclassified

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Tuberculous otitis media: A case presentation and review of european literature

Aguilera-Franco,

Franco-Acosta,

Yépez-Naranjo

et al. 2023

Rev Esp Quimioter

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“…Otomastoiditis is an inflammatory condition of the tympanic cavity and mastoid air cells with a broad range of etiologies [ 1 - 5 ]. One common cause is bacterial infection.…”

Section: Introductionmentioning

confidence: 99%

Allergic Fungal Otomastoiditis: A Case Report

Sakaida,

Takeuchi

2023

Cureus

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Otomastoiditis caused by an allergic reaction to fungi in the middle ear is rare, with only four cases reported in the English literature. We report the case of a patient with allergic fungal otomastoiditis. A 28-year-old man presented with otalgia, hearing loss, and vertigo. Exploratory tympanotomy revealed mucin with a peanut butter-like consistency and containing eosinophils and Candida parapsilosis , but no evidence of direct tissue invasion by fungi. The patient was treated with a combination of surgery and medication. Subtotal petrosectomy was finally performed to remove the middle ear mucosa and separate the middle ear from the external environment. Short-term prednisolone and long-term fluconazole were administered without satisfactory therapeutic results. The inflammatory condition has improved but continues without complete remission. Allergic fungal otomastoiditis is an extremely rare condition that may share pathophysiological features with allergic fungal rhinosinusitis, so a thorough examination combining bacterial cultures, histopathological examination with fungal staining, and serum antigen-specific immunoglobulin E against multiple fungi is essential. Optimal treatment probably comprises appropriate surgery and long-term administration of systemic corticosteroids. Definitive diagnostic criteria and therapeutic strategies need to be established, based on the accumulation of similar cases.

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