Tuberculous laryngitis: A series of 37 patients

Cm, Bailey; Pc, Windle-Taylor

doi:10.1288/00005537-198101000-00014

Cited by 70 publications

(19 citation statements)

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“…The predominance of men in the fifth or sixth decade of life, with no significant age difference between genders, observed in our study, has been frequently reported [ 16 , 20 , 21 ], although a lower age of female patients has been described [ 16 ]. Most of the patients had low socioeconomic conditions, such as low income and low education level which were factors described as facilitators for the development of the disease [ 15 , 22 , 23 ].…”

Section: Discussionsupporting

confidence: 54%

“…Due to the lack of standardization of the endoscopic findings, it is difficult to compare our results with those in the literature. In the 1980s, a classical description consisted in multiple lesions, frequently ulcerated [ 21 ]. Currently, ulcerated lesions are still observed [ 13 , 25 , 35 ], but some authors suggest that the lesions are hypertrophic or exophytic in most cases, and difficult to distinguish from chronic laryngitis of other etiologies [ 10 , 15 , 35 ].…”

Section: Discussionmentioning

confidence: 99%

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Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis

Reis

Costa

et al. 2016

PLoS ONE

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IntroductionLaryngeal tuberculosis (LTB) is the most frequent granulomatous disease of the larynx and represents less than 2% of extrapulmonary TB cases. There are no pathognomonic clinical and endoscopic features of this disease and studies on LTB that can assist in its diagnostic characterization are lacking.ObjectiveTo identify factors associated with clinical and topographical features of LTB.Methoda retrospective cross-sectional study was conducted from the medical records of 36 patients with confirmed LTB diagnosis.ResultsDysphonia and cough were the main symptoms presented by patients and the true vocal folds the most frequently affected site. The average of the duration of the disease evolution was significantly higher in patients with dysphonia than in patients without this symptom. We observed association between dysphonia and true vocal fold lesions and between odynophagia and lesions in the epiglottis, arytenoids and aryepiglottic folds. Odynophagia was more frequent in individuals with lesions in four or more laryngeal sites. Weight loss equal or above 10% of the body weight was more frequent in patients with odynophagia as first symptom and in patients with ulcerated lesion. Dyspnea on exertion was more frequent in individuals with more extensive laryngeal lesions. The percentage of smokers with lesions in four or more laryngeal sites was greater than that found in non-smokers. Laryngeal tissue fragment bacilloscopy and culture examinations were less positive than sputum ones.ConclusionsSmoking appears to be associated with the development of more extensive LTB lesions, and LTB with dyspnea on exertion and odynophagia with consequent impairment of nutritional status. We emphasize the need for histopathologic confirmation, once positive sputum bacteriological examinations seem not to necessarily reflect laryngeal involvement.

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Section: Discussionsupporting

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Factors Associated with Clinical and Topographical Features of Laryngeal Tuberculosis

Reis

Costa

et al. 2016

PLoS ONE

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“…In our study, hoarseness was found to be the most common symptom (90% of patients), as indicated in other reports [ 3 , 7 , 8 , 12 – 14 ]. The majority of our cases were single lesions (75%), localized in true vocal folds (60%), which in recent studies has been found to be a typical presentation of laryngeal tuberculosis [ 3 , 7 , 8 , 13 , 14 ]. The prevalence of involvement of the posterior larynx, so commonly reported in the past, is presently not observed.…”

Section: Discussionmentioning

confidence: 67%

Tuberculosis of the head and neck – epidemiological and clinical presentation

Bruzgielewicz¹,

Rzepakowska²,

Osuch-Wójcikewicz³

et al. 2014

aoms

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IntroductionThe aim of our retrospective study was to review the clinical and epidemiological presentation of head and neck tuberculosis.Material and methodsWe analyzed the history of 73 patients with head and neck tuberculosis hospitalized in the Department of Otolaryngology, Medical University of Warsaw, between 1983 and 2009.ResultsWe found that 26 (35.6%) patients presented with lymph node tuberculosis, 20 (27.4%) with laryngeal tuberculosis, 10 (13.7%) with oropharyngeal tuberculosis, 9 (12.3%) with salivary gland tuberculosis, 3 (4.1%) with tuberculosis of paranasal sinuses, 3 (4.1%) with aural tuberculosis, and 2 (2.7%) with skin tuberculosis in the head and neck region. Within the group of patients with lymph node tuberculosis in 15 cases there were infected lymph nodes of the 2nd and 3rd cervical region and in 11 infected lymph nodes of the 1st cervical region. In 5 cases of laryngeal tuberculosis there was detected coexistence of cancer. Oropharyngeal tuberculosis in 7 cases was localized in tonsils, where in 1 case coexisting cancer was diagnosed. Chest X-ray was performed in all cases and pulmonary tuberculosis was identified in 26 (35.6%) cases.ConclusionsWe conclude that tuberculosis still remains a problem and must be taken into consideration in the diagnostic process. The coincidence of tuberculosis and cancer is remarkable in the head and neck region.

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“…Die Larynxtuberkulose stellt nach dem Lymphknotenbefall mit 1 % aller Tuberkulosefälle den zweithäufi gsten Manifestationsort im Kopf-Hals-Bereich dar [19]. Die anteriore Larynxhälfte ist dabei doppelt so häufi g betroff en wie die posteriore Hälfte [ 20 ] . Obwohl alle Larynxetagen involviert sein können, ist mit 50-70 % vor allem die Stimmlippenebene betroff en [ 21 ] .…”

Section: Larynxtuberkuloseunclassified