Tubular dysfunction and microalbuminuria in insulin dependent diabetes.

Chiarelli, F; Penna, G. La; Morgese, G

doi:10.1136/adc.64.4.635

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Cited by 3 publications

(2 citation statements)

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“…As shown by previous studies, ␣1-microglobulin correlated with HbA 1c and concurrent urinary glucose (12,13). In the present study, TGF-␤1 excretion and urinary glucose were independent determinants for urinary ␣1-microglobulin in the multiple regression model.…”

Section: Urinary Aersupporting

confidence: 83%

See 1 more Smart Citation

Urinary transforming growth factor-beta1 and alpha1-microglobulin in children and adolescents with type 1 diabetes.

Korpinen

Teppo²,

Hukkanen³

et al. 2000

Diabetes Care

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Section: Urinary Aersupporting

confidence: 83%

“…This is a new finding suggesting a link between TGF-␤1 excretion and tubular damage. Urinary excretion of ␣1-microglobulin can be decreased if metabolic control improves (13). In contrast to urinary TGF-␤1, which is of renal origin (7), ␣1-microglobulin is derived from plasma and reabsorbed in proximal tubulus.…”

Section: Urinary Aermentioning

confidence: 99%

Urinary transforming growth factor-beta1 and alpha1-microglobulin in children and adolescents with type 1 diabetes.

Korpinen

Teppo²,

Hukkanen³

et al. 2000

Diabetes Care

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show abstract

Urinary growth hormone measurements as a marker of renal tubular function in diabetes mellitus

Turner

Coates

Porter

et al. 1993

Clinica Chimica Acta

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Glomerular and Tubular Proteinuria in Type 1 (Insulin-Dependent) Diabetic Patients with and without Retinopathy

et al. 1992

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SUMMARY. We compared the urinary excretion of albumin, transferrin, N-acetyl--D-glucosaminidase and o-l-microglcbulin in 78 Type 1 (insulin-dependent) diabetic patients: 39 with retinopathy and 39 without. The two groups were matched for age, sex and duration of diabetes. The patients with retinopathy had increased excretion (median and range) of albumin [1'7 (0' 3-399·1) versus 1·0 (0' 3-116'6) mg/mmol creatinine, P<0'05j, transferrin [114'2 (4'1-37126'2) versus 33·4 (1'0-4176'7) JLg/mmol creatinine, P< 0'01] and N-acetyl-~-D-glucosaminidase [23' 8 (1'1-119'1) versus 15·0 (0'1-65 '1) JLmol/h/mmol creatinine, P

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Tubular dysfunction and microalbuminuria in insulin dependent diabetes.

Cited by 3 publications

References 3 publications

Urinary transforming growth factor-beta1 and alpha1-microglobulin in children and adolescents with type 1 diabetes.

Urinary transforming growth factor-beta1 and alpha1-microglobulin in children and adolescents with type 1 diabetes.

Urinary growth hormone measurements as a marker of renal tubular function in diabetes mellitus

Glomerular and Tubular Proteinuria in Type 1 (Insulin-Dependent) Diabetic Patients with and without Retinopathy

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