Tumeric or Curcuma longa Linn.

El-Kenawy, Ayman El-Meghawry; Hassan, Snur Ma; Mohamed, Ahmed Mohmed Mohamed; Mohammed, Hala Mahmoud Ahmed

doi:10.1016/b978-0-12-812491-8.00059-x

Cited by 6 publications

(3 citation statements)

References 38 publications

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“…Amongst them, turmeric (Curcuma longa L., Zingiberaceae) is especially popular worldwide because of its attractive culinary, cosmetic and medicinal uses [3]. Specifically, the interest of this tuberous species resides in its exploitation as a colouring and flavouring agent, as well as in its numerous pharmacological activities, such as antioxidant, anticancer, anti-inflammatory, neuro-and dermoprotective, antiasthmatic or hypoglycaemic [4][5][6][7][8][9][10], being recently reported that turmeric can even potentially contribute against the life-threatening viral disease COVID-19 by inhibiting the main protease enzyme [11]. Most of these interesting features and properties principally come from the rhizome [3,12], a horizontal underground stem from which the shoots and roots arise [13].…”

Section: Introductionmentioning

confidence: 99%

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Ibáñez

Blázquez

2020

Plants

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Curcuma longa L. rhizome essential oil is a valuable product in pharmaceutical industry due to its wide beneficial health effects. Novel applications in the agri-food industry where more sustainable extraction processes are required currently and safer substances are claimed for the consumer are being investigated. This review provides information regarding the conventional and recent extraction methods of C. longa rhizome oil, their characteristics and suitability to be applied at the industrial scale. In addition, variations in the chemical composition of C. longa rhizome and leaf essential oils regarding intrinsic and extrinsic factors and extraction methods are also analysed in order to select the most proper to obtain the most efficient activity. Finally, the potential applications of C. longa rhizome oil in the agri-food industry, such as antimicrobial, weedicide and a food preservative agent, are included. Regarding the data, C. longa rhizome essential oil may play a special role in the agri-food industry; however, further research to determine the application threshold so as not to damage crops or affect the organoleptic properties of food products, as well as efficient encapsulation techniques, are necessary for its implementation in global agriculture.

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Section: Introductionmentioning

confidence: 99%

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Ibáñez

Blázquez

2020

Plants

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“…Turmeric is a natural flowering plant of the ginger family, used as a dietary supplement (Ayman et al, 2019). The plant contains active components such as curcumin, proven scientifically to possess health benefits.…”

Section: Turmericmentioning

confidence: 99%

Impacts of Natural Ingredients and Supplements on Health and Wellness

2024

PSSRP

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“…Despite its efficacy and safety, several preclinical and clinical studies have shown that the pharmacokinetic profile of curcumin is unfavorable, leading to its poor bioavailability Turmeric has long been used as a traditional medicinal herb to treat various ailments such as wound healing, dermatological diseases, pneumonia, hepatic disorders, coughs, and arthritis [40]. Curcumin itself is known to possess several biological and pharmacological activities including anti-microbial, anti-fungal, anti-viral, antioxidant, anti-cancer, anti-inflammatory, anti-diabetic, and anti-obesity effects, as well as cardioprotective and neuroprotective properties [41]. Many studies have reported that the anti-obesity effects of curcumin are mediated by inhibiting adipogenesis, regulating lipid metabolism, stimulating energy expenditure, and improving gut microbiota as recently reviewed [42].…”

Section: The Pharmacokinetic Profile Of Curcuminmentioning

confidence: 99%

Therapeutic Effects of Curcumin Derivatives against Obesity and Associated Metabolic Complications: A Review of In Vitro and In Vivo Studies

Moetlediwa,

Ramashia,

Pheiffer

et al. 2023

IJMS

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Obesity is a major cause of morbidity and mortality globally, increasing the risk for chronic diseases. Thus, the need to identify more effective anti-obesity agents has spurred significant interest in the health-promoting properties of natural compounds. Of these, curcumin, the most abundant and bioactive constituent of turmeric, possesses a variety of health benefits including anti-obesity effects. However, despite its anti-obesity potential, curcumin has demonstrated poor bioavailability, which limits its clinical applicability. Synthesizing curcumin derivatives, which are structurally modified analogs of curcumin, has been postulated to improve bioavailability while maintaining therapeutic efficacy. This review summarizes in vitro and in vivo studies that assessed the effects of curcumin derivatives against obesity and its associated metabolic complications. We identified eight synthetic curcumin derivatives that were shown to ameliorate obesity and metabolic dysfunction in diet-induced obese animal models, while five of these derivatives also attenuated obesity and associated metabolic complications in cell culture models. These curcumin derivatives modulated adipogenesis, lipid metabolism, insulin resistance, steatosis, lipotoxicity, inflammation, oxidative stress, endoplasmic reticulum stress, apoptosis, autophagy, fibrosis, and dyslipidemia to a greater extent than curcumin. In conclusion, the findings from this review show that compared to curcumin, synthetic curcumin derivatives present potential candidates for further development as therapeutic agents to modulate obesity and obesity-associated metabolic complications.

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Tumeric or Curcuma longa Linn.

Cited by 6 publications

References 38 publications

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Impacts of Natural Ingredients and Supplements on Health and Wellness

Therapeutic Effects of Curcumin Derivatives against Obesity and Associated Metabolic Complications: A Review of In Vitro and In Vivo Studies

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