2021
DOI: 10.1016/j.anndiagpath.2021.151792
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Tumor Budding is a reliable predictor for death and metastasis in invasive ductal breast cancer and correlates with other prognostic clinicopathological parameters

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Cited by 15 publications
(18 citation statements)
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“…We also demonstrated that TB was associated with age, menopausal status, T stage, TNM stage, and LNM status. Consistent with previous studies ( 39 ), our study showed that TB was an independent prognostic factor of BC patients. In BC, which is highly heterogeneous, prognosis varies widely among different subtypes.…”
Section: Discussionsupporting
confidence: 93%
“…We also demonstrated that TB was associated with age, menopausal status, T stage, TNM stage, and LNM status. Consistent with previous studies ( 39 ), our study showed that TB was an independent prognostic factor of BC patients. In BC, which is highly heterogeneous, prognosis varies widely among different subtypes.…”
Section: Discussionsupporting
confidence: 93%
“…Breast cancer is the most prevalent type of cancer and the most lethal and recurrent cause of death. Invasive ductal papillary cancer is the subtype and most common type of breast cancer, and it comprises approximately 80% of all cases [ 1 , 2 ]. Despite advancements in diagnostic and treatment options, breast cancer-related death is still high.…”
Section: Introductionmentioning
confidence: 99%
“…Tumor budding is observed much less frequently in endometrioid endometrial carcinomas compared to colon, breast, stomach, and lung carcinomas. 5, 8, 25 This suggests that the reason why endometrioid endometrial carcinomas generally have a better prognosis and survival. However, as detected in our study, even among tumors of low stage and low grade in endometrioid endometrial carcinomas, a single tumor budding (1/0.95 mm 2 ) creates a significant difference in survival.…”
Section: Discussionmentioning
confidence: 99%
“…It has also been identified as an independent poor prognostic parameter in these tumors. [5][6][7][8] Different assessment and scoring systems have been proposed for tumor budding for many years, and in 2016, tumor budding assessment method and scoring in colorectal carcinomas have been standardized in the International Tumor Budding Consensus Conference (ITBCC). 9 Then, it took place as an additional prognostic factor for colorectal cancers in recent CAP cancer reporting protocol in 2019.…”
Section: Introductionmentioning
confidence: 99%