Tumoral calcinosis: A case report and review of the literature

Viegas, Steven F.; Evans, E. Burke; Calhoun, Jason H.; Goodwiller, Steven E.

doi:10.1016/s0363-5023(85)80225-2

Cited by 61 publications

(22 citation statements)

References 25 publications

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“…A number of cases of underlying bone involvement have, however, been reported [13,36,44]. In our series of six patients, all lesions were adherent to the underlying bone, and CT scan revealed the presence of superficial cortical erosion in five, a highly unusual and rarely reported feature of classic tumoral calcinosis.…”

Section: Discussionmentioning

confidence: 50%

“…An apparent inherited disorder of phosphate and vitamin D metabolism has also been described [8,19,28,34,37,38,48]. Trauma has been implicated as a cause in selected patients [5,10,15,30,36,39,42,44]. Although surgical specimens of the patients reported here revealed findings typical of tumoral calcinosis, the patients' age and race are atypical, and the lesions were solitary, unusually small, and in an atypical location.…”

Section: Discussionmentioning

confidence: 72%

“…It has also been reported that the lesions do not involve adjacent bone [4,6,16,21,23,29,36,38]. Although a metabolic etiology has been proposed, some authors feel that the condition may occasionally be related to trauma [5,10,15,30,36,39,42,44].…”

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confidence: 99%

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Tumoral calcinosis-like lesion of the proximal linea aspera

et al. 1990

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Abstract. Tumoral calcinosis is presently a poorly defined disease. In its classic form, it consists of multiple large foci of benign mineralization in the soft tissuc adjacent to bone near large joints. Patients are generally of African descent and are adolescents or young adults at presentation. Both metabolic and traumatic etiologies have been proposed. We report six adult Caucasian patients with lesions that pathologically resembled tumoral calcinosis. All lesions were small (less than 3 x 3 cm) and were located along the proximal 1inca aspera of the femur. All patients presented with pain. Because of the atypical patient population and the unusual size and location of the lesions, we refer to this process as a "tumoral calcinosis-like lesion." A typical radiographic appearance and location, together with appropriate clinical history, can strongly suggest this diagnosis.

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Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 72%

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Tumoral calcinosis-like lesion of the proximal linea aspera

et al. 1990

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“…Serum calcium, parathormone [3,9,10,11] and ALP [8] levels are usually normal. Renal function is also usually normal [4].…”

Section: Discussionmentioning

confidence: 99%

Tumoral calcinosis: a case report

et al. 2007

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Tumoral Calcinosis is a distinct clinical and histological entity that is characterized by large periarticular deposits of calcium resembling a neoplasm and is found foremost in the region of hip, shoulder and elbow. We report a case of Tumoral Calcinosis in a 25-year-old male who presented to us with gradually increasing swelling of right axilla, and both hips of nearly two years duration. It was diagnostic enigma for the treating surgeons but with the help of an astute pathologist we diagnosed this rare condition and successfully treated it surgically. Keywords Case reportA 25-year-old male came to our outdoor with complaints of gradually increasing swelling on both hips and right axilla for last 2 years. Two years back he noticed some restriction of right shoulder joint movement for which he had some massage therapy. Couple of days later he noticed a lump of about 2 inches size in right axilla. About 2 weeks later he noticed two similar lumps on the sides of both hip joints. As these swellings were gradually increasing in size he sought local medical help and treating physician thought it to be chronic abscesses and did I & D of these swellings. Since then thick chalky white discharge used to come.Examination revealed three lumps, one in axilla of about 3 x 2 inches, fi rm in consistency, nontender, nonmobile with ulcerated surface, fl oor of which was covered with chalkywhite exudates. Two hip masses were about 5 x 3 inches with similar characteristics as that of axillary lump. There were no other signifi cant clinical fi ndings.Investigation revealed normal hemoglobin, normal total and differential count and normal routine urine. Renal function was normal. Plain X-ray of both hips and axilla revealed spotty calcifi cation in periarticular soft tissues. Serum calcium was 8.4 mg/dL and inorganic phosphorus 4.2 mg/dL. Serum parathormone level was normal. Histopathology showed diffuse and extensive areas of spotty calcifi cation and fi brocollagenous tissue interspersed with macrophages and mixed infl ammatory cell infi ltrate, appearance suggestive of Tumoral Calcinosis. Chemical analysis showed Calcium Phosphate crystals. Diagnosis of Tumoral Calcinosis was thus made. We performed complete excision of these lumps in 2 settings and patient is doing fi ne postoperatively. We will follow him up 3 monthly for any evidence of recurrence.

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“…Tumoral calcinosis tends to occur more often in people of African descent and is commonest in the second decade of life, but can affect any age [4,5,6]. It is commonly seen as a complication of renal dialysis, but occasionally the idiopathic form occurs.…”

Section: Introductionmentioning

confidence: 99%

Large Tumoral Calcinosis in The Gluteal Region: A Case Report

Ym¹,

Ef²,

M³

et al. 2013

Ortop Traumatol Rehabil

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SUMMARYBackground. Tumoral calcinosis is a poorly understood phenomenon. It can be described as a syndrome of calcium deposits principally affecting the juxta-articular areas. It is a rare entity that has been poorly understood. Our aim is to highlight a special and unusual case of an 11-year-old with a large, relatively painless lump in her buttock.Clinical case. An 11-year-old girl of African descent presented to our Bone Tumour Unit after being referred by her local hospital. The girl presented with a large lump on the posterolateral aspect of the right buttock, measuring 15cm in diameter. Due to the delay in referral/diagnosis, tethering of the skin had progressed to necrosis, with a sinus discharging milky-white fluid. A MRI scan further characterised the lump as a densely calcified area within the gluteus maximus, extending to the subcutaneous tissue. The characteristic features of the calcified mass on the images led to the diagnosis of tumoral calcinosis. Laboratory test did not demonstrate any metabolic disturbances. Pathology reports further confirmed the diagnosis and the lump was successfully resected. There were no recurrences on follow-up.Conclusion. Several cases of tumoral calcinosis have been described in the literature; however, it remains a rare entity. Being aware of the possibility and having knowledge of tumoral calcinosis is paramount in preventing confusion and delay in diagnosis for patients and clinicians.

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Tumoral calcinosis: A case report and review of the literature

Cited by 61 publications

References 25 publications

Tumoral calcinosis-like lesion of the proximal linea aspera

Tumoral calcinosis-like lesion of the proximal linea aspera

Tumoral calcinosis: a case report

Large Tumoral Calcinosis in The Gluteal Region: A Case Report

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