Tumorbedingte Fatigue und ihre psychosozialen Belastungen

Abstract

Cancer-related fatigue (CRF) is a highly prevalent and the most distressing symptom during and after treatment for cancer. It is characterized by feelings of physical and mental tiredness, weakness, and lack of energy and is not influenced by rest or sleep. Approximately 40% of patients suffer from CRF at diagnosis and nearly all patients experience fatigue during the course of cancer therapy. The impact of CRF on daily living and patient quality of life (QoL) is substantial. It profoundly affects patient quality of life and limits personal, social and occupational roles. The fatigue is also associated with significant levels of distress and it imposes a financial burden by limiting the ability to work. The underlying causes of CRF are poorly understood as are the relationship between fatigue and psychosocial distress, depression or anxiety. This paper seeks to give an overview of cancer-related fatigue and its psychosocial burden.

The personal impact of living with a myeloproliferative neoplasm

“…The high percentage (48.8%) of patients who were restricted in their ability to work raises the question of what is behind this. Based on what has been found in the literature, 30 it is plausible that fatigue, which is a common complaint of patients in our study, plays an important role. It has been noted that cancer‐related fatigue can have a profound impact on QoL, not only in terms of occupational functioning, but also in terms of personal and social roles.…”

“…To gain insight into how the disease burden of MPN patients relates to that of other cancer patients, we compared our EORTC QLQ-C30 scores with data from the reference group of all cancer patients at all stages. 30 To measure sociodemographic variables, questions were asked about age, sex, level of education (low, middle or high), and civil state (having a partner and living together or separated, being single).…”

“…To gain insight into how the disease burden of MPN patients relates to that of other cancer patients, we compared our EORTC QLQ‐C30 scores with data from the reference group of all cancer patients at all stages 30 …”

Assessment of cancer related fatigue

“…________________________ Spreading of cancer-related fatigue described in medical literature varies widely 14-99% (5,8). At the stage of diagnosis, up to 40% of patients complain of fatigue, this percentage grows up to 90% in the course of treatment (9). Almost all patients experience fatigue during the treatment of an oncological disease -with 90% of patients treated with radiotherapy, and with 80% of patients treated with chemotherapy.…”

Was hilft wirklich bei tumorbedingter Fatigue? Ein Überblick über systematische Übersichtsarbeiten

“…Fatigue tritt noch Monate oder sogar Jahre nach Abschluss der Behandlung bei etwa einem Drittel der Patient(inn)en mit Krebs auf (Hofman, Ryan, Figueroa-Moseley, JeanPierre & Morrow, 2007). Fatigue hat einen erheblichen negativen Einfluss auf den Gesundheitszustand, das Befinden, den Krankheitsverlauf, die Lebensqualität, die Alltagsbewälti-gung und die ökonomische Situation von Krebspatient(inn)en (de Vries, Reif & Petermann, 2011a;de Vries, Reif & Petermann, 2011b;de Vries, Reif, Stuhldreher, Petermann & Görres, 2009). Pflegekräfte kommen in der Betreuung von Krebspatient(inn)en mit allen Aspekten der Fatigue in der Akutversorgung, in der Langzeitbetreuung wie auch in der Palliativsituation in Kontakt.…”