Tumors of the Alimentary Tract

Head, K. W.; Else, R. W.; Dubielzig, Richard R.

doi:10.1002/9780470376928.ch8

Cited by 242 publications

(476 citation statements)

References 312 publications

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“…3,4,6 It is considered to be a malignant neoplasm, because the neoplasms are locally invasive and have excessive and rapid growth. 4,6 Although squamous cell carcinoma does not commonly metastasize to distant sites, it frequently metastasizes to regional lymph nodes.…”

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Oral Squamous Cell Carcinoma in a Vietnamese Pot-Bellied Pig (Sus Scrofa)

et al. 2009

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Abstract. An 18-year-old, neutered, male Vietnamese pot-bellied pig (Sus scrofa) was treated for chronic, intermittent nasal discharge and sneezing. The animal was diagnosed with severe periodontal disease (grade IV), an oronasal fistula, and multiple tooth root abscesses via dental examination and computed tomography of the skull. Dentistry was performed, including multiple tooth extractions, and antibiotic therapy was initiated. Eighteen months later, the animal was evaluated for lethargy, anorexia, and a firm, 12 cm 3 12 cm mass between the 2 rami of the mandible. Laboratory testing revealed moderate anemia, severe leukocytosis, and hyperglobulinemia. Skull radiographs indicated osteomyelitis of the mandible and soft-tissue swelling. A fine-needle aspirate and biopsy were taken, and results were consistent with squamous cell carcinoma. Treatment with piroxicam and antibiotics was initiated as needed to control signs of pain and secondary infection, respectively. Three months after diagnosis, the pig was euthanized due to cachexia and severe depression secondary to squamous cell carcinoma. On postmortem examination, the right mandibular area contained multiple, coalescing, irregular masses extending from the ramus rostrally to the mandibular canine teeth and ventrally within the intermandibular space, completely obliterating the normal anatomy. An open midshaft fracture was present on the right mandible. On histopathology, the masses were confirmed as locally invasive and destructive squamous cell carcinoma. No evidence of metastasis was noted in regional lymph nodes or in any of the distant sites evaluated.

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Oral Squamous Cell Carcinoma in a Vietnamese Pot-Bellied Pig (Sus Scrofa)

et al. 2009

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“…Recently, we encountered an adenocarcinoma arising from a minor salivary gland of a Richardson's ground squirrel. Although salivary gland tumors have been reported in various animals such as rats, mice, dogs, cats, horses, cattle, sheep, and humans, the frequency of the tumors is very low [3,4,7,11]. Recently, it has been considered that transforming growth factor-β1 (TGF-β1) and cyclooxygenase-2 (COX-2) may be related to the morphogenesis of tumors [6,9,12,14].…”

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confidence: 99%

“…Histopathologically, salivary gland-derived adenocarcinoma is characterized by a spectrum from well-differentiated acinar, ductular, cystic or trabecular pattern to solid or lobular growth with poor differentiation with infiltrative growth into the surrounding tissues. Thus, the term adenocarcinoma is used for salivary gland tumors that do not have the diagnostic criteria of subtypes of glandular tumors [4,5]. The present primary tumor consisted exclusively of acinar, ductular, cystic, and intraductular papillary growth patterns, indicating the presence of characteristics of acinar cell carcinoma or cystoadenocarcinoma.…”

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confidence: 99%

“…10) with varying degree; a greater reaction was seen in the neoplastic cells forming the solid or lobular growth. Malignant epithelial tumors arising in the salivary glands are classified into acinar cell carcinoma, mucoepidermal carcinoma, cystadenocarcinoma, adenocarcinoma, malignant myoepithelioma, squamous cell carcinoma, and undifferentiated carcinoma [4,5]. The subtype of squamous cell carcinomas has been experimentally induced in rats by chemicals such as 9,10-dimethyl-1,2-benzanthracene and 4-nitroquinoline-1-oxide [2,19].…”

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Spontaneous Adenocarcinoma Immunoreactive to Cyclooxygenase-2 and Transforming Growth Factor-.BETA.1 in the Buccal Salivary Gland of a Richardson's Ground Squirrel (Spermophilus richardsonii)

et al. 2007

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“…Odontogenic tumors, including epithelial odontogenic tumors are rare in animals [5,[8][9][10]12]. Only two reference cases of ameloblasoma in rabbits have been submitted to the Armed Forces Institute of Pathology Wednesday Slide Conference, Case I-388 (AFIP 2578783) and Case II-97N172 (AFIP 2638859).…”

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Peripheral Acanthomatous Ameloblasoma in a Rabbit with Review of Previous Submissions of the Armed Forces Institute of Pathology Wednesday Slide Conference

Madarame

Enaga

2009

J. Vet. Med. Sci.

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ABSTRACT. A case of peripheral acanthomatous ameloblasoma of the angulus orisa in a 6-year-old female rabbit was described. The tumor composed of confluent follicles of stellate reticulum with peripheral cuboidal to reverse polarized columnar cells with nuclear palisading in the submucosa of the angulus orisa. The follicular cell elements stained positive for pan-cytokeratin. Additionally, there were multifocal keratinizing foci of the stellate reticulum with some mineralization. Calcified product such as enamel or dentin was not formed. Acanthomatous ameloblasoma in the submucosa of the angulus orisa has not been described and it may develop from an ectopic rest of odontogenic tissue. After excision, neither local recurrence nor metastasis has been observed.

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Tumors of the Alimentary Tract

Cited by 242 publications

References 312 publications

Oral Squamous Cell Carcinoma in a Vietnamese Pot-Bellied Pig (Sus Scrofa)

Oral Squamous Cell Carcinoma in a Vietnamese Pot-Bellied Pig (Sus Scrofa)

Spontaneous Adenocarcinoma Immunoreactive to Cyclooxygenase-2 and Transforming Growth Factor-.BETA.1 in the Buccal Salivary Gland of a Richardson's Ground Squirrel (Spermophilus richardsonii)

Peripheral Acanthomatous Ameloblasoma in a Rabbit with Review of Previous Submissions of the Armed Forces Institute of Pathology Wednesday Slide Conference

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