Tunable selective detection for capillary gas chromatography by ion mobility monitoring

Baim, Michael A.; Hill, Herbert H.

doi:10.1021/ac00238a013

Cited by 124 publications

(42 citation statements)

References 17 publications

(12 reference statements)

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“…The fact that the mobility time of the solvent peaks increased with experimental duration suggested that the solvent ions were surrounded by an increasing amount of solvation molecules. Conventional gas phase ion mobility spectrometry has a unidirectional counter flow of drift gas that keep the drift region clean by continuously sweeping out neutral molecules [84]. Because the liquid hexane medium was stationary in this study, any uncharged solvent molecules would remain inside the spectrometer.…”

Section: Lpims Spectra Of Solvent Blankmentioning

confidence: 99%

Liquid phase ion mobility spectrometry

Tam

Hill

2011

Analyst

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Section: Lpims Spectra Of Solvent Blankmentioning

confidence: 99%

Liquid phase ion mobility spectrometry

Tam

Hill

2011

Analyst

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“…Several sources have been used as the primary ionization source, including thermionic emission, 22 flame ionization, 4 photoionization, 23 surface ionization 24 laser multiphoton ionization, 25 electrospray, 26 and corona-discharge. 27 Early IMS instrumentation sometimes involved other sources; 63 Ni was the ionization source in the first patent and is still used in some instruments today.…”

Section: Ionization Sourcementioning

confidence: 99%

Data for Users of Handheld Ion Mobility Spectrometers

b'Daum¹,

b'Fox²

2008

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v EXECUTIVE SUMMARYChemical detection technology end-user surveys conducted by Idaho National Laboratory (INL) in 2005 and 2007 indicated that first responders believed manufacturers' claims for instruments sometimes were not supported in field applications, and instruments sometimes did not meet their actual needs. Based on these findings, the Department of Homeland Security (DHS) asked INL to conduct a similar survey for handheld ion mobility spectrometers (IMS), which are used by a broad community of first responders as well as for other applications. To better access this broad community, the INL used the Center for Technology Commercialization, Inc. (CTC), Public Safety Technology Center (PSTC) to set up an online framework to gather information from users of handheld IMS units. This framework (Survey Monkey) was then used to perform an online Internet survey, augmented by e-mail prompts, to get information from first responders and personnel from various agencies about their direct experience with handheld IMS units. Overall, 478 individuals responded to the survey. Of these, 174 respondents actually owned a handheld IMS. Performance and satisfaction data from these 174 respondents are captured in this report.The survey identified the following observations:The most common IMS unit used by respondents was the Advanced Portable Detector (APD-2000), followed by ChemRae, Sabre 4000, Sabre 2000, Draeger Multi IMS, Chemical Agent Monitor-2, Chemical Agent Monitor, Vapor Tracer, and Vapor Tracer-2.The primary owners were HazMat teams (20%), fire services (14%), local police (12%), and sheriffs' departments (9%).IMS units are seldom used as part of an integrated system for detecting and identifying chemicals but instead are used independently.Respondents are generally confused about the capabilities of their IMS unit. This is probably a result of lack of training.Respondents who had no training or fewer than 8 hours were not satisfied with the overall operation of the handheld IMS unit.IMS units were used for detecting a range of analytes. The most common use was for detection of hazardous chemicals, followed by detection of explosives, illicit drugs, chemical warfare, nerve agents, and radiation. One IMS unit had dual capability as a radiation detector.Respondents who did not own an IMS listed prohibitive cost of equipment as the main factor for not having one.Respondents who were highly satisfied with the overall operation of the handheld IMS obtained the IMS through a direct purchase. In comparison, the respondents who were not satisfied had obtained the handheld IMS through a DHS grant. vi vii ACKNOWLEDGMENTSWe would like to thank the HazMat personnel, first responders, fire fighters, local and state police, sheriffs, border patrol agents, and other agency personnel for completing the online handheld IMS survey. We also thank Melinda Cook and Thomas Creighton from

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“…16 The clearance-time problem in IMS was solved by Hill and co-workers when they constructed an IMS with a reduced ionization volume and introduced the concept of unidirectional flow in ion mobility spectrometry. 17 In the unidirectional flow design of IMS, the sample is introduced between the ionization region and the first ion gate of the spectrometer (see Figure 1). The IMS drift gas enters the spectrometer at the collector electrode end, flows completely through the spectrometer in one direction, counter to that of ion migration, and exits at the opposite end of the spectrometer, sweeping the neutral sample molecules into the ionization region and out of the spectrometer in minimal time.…”

Section: Portable Gc/imsmentioning

confidence: 99%