Tuning the Conductivity, Morphology, and Capacitance with Enhanced Antibacterial Properties of Polypyrrole by Acriflavine Hydrochloride

Abstract

In this study, a simple one-step preparation of polypyrrole (PPy) assisted by an organic dye, acriflavine hydrochloride (AF), was investigated. The presence of a dye resulted in the development of PPy nanofibers with the conductivity enhanced up to 14 S cm −1 . The structural analysis by Fourier-transform infrared and Raman spectroscopies confirmed the interaction of the AF with PPy. As far as the electrochemical activity of PPy is concerned, the gravimetric capacitance increased up to 85 F g −1 with the help of a AF. Additionally, a substantial improvement in the antibacterial activity against Staphylococcus aureus and Escherichia coli bacteria for all the PPy-containing organic dye was achieved. The conductivity, morphology, capacitance, and remarkable antibacterial properties of PPy tuned by an organic dye enable applications wherever the electroconductivity and antibacterial activity should meet requirements, for example, wound healing, electrochemical sensors, bioactuators, or even regenerative medicine.

Facile Synthesis of Carbon Dot Deposited γ-FeOOH Nanosheet/Polypyrrole Composite: A Robust Photocatalyst for Degradation of Antibiotics under Sunlight Irradiation with Enhanced Antibacterial Activity

“…The ZOI for 400, 800, and 1200 ppm PFL/CDs-2 was 14, 15, and 17 mm against B. pumilus (Figure a) and 15, 18, and 19 mm against E. coli (Figure d), respectively. It has been previously demonstrated that γ-FeOOH, PPy, CDs, and their composites are effective antimicrobial agents. − The antibacterial activity of PFL/CDs-2 composite was further compared with γ-FeOOH, PPy, and CDs at an optimum concentration of 800 ppm, and results suggested that PFL/CDs-2 showed excellent antimicrobial activity against two bacterial pathogens. The ZOI of different materials at 800 ppm was measured to be 13, 11, and 7 mm for γ-FeOOH, CDs, and PPy, respectively, against B. pumilus (Figure b,g), whereas it was 14, 12, and 8 mm for γ-FeOOH, CDs, and PPy respectively against E. coli (Figure e,h).…”

Rational Design of Conducting Polymer-Derived Tubular Carbon Nanoreactors for Enhanced Enzyme-like Catalysis and Total Antioxidant Capacity Bioassay Application

“…The peaks located at around 287, 406, and 604 cm –1 are ascribed to the E g mode, and the peak at around 659 cm –1 is assigned to the E u mode of α-Fe 2 O 3 , while the peak at 1311 cm –1 is indexed as the α-Fe 2 O 3 second harmonic vibration . After in situ polymerization, two broad peaks appear at 1322 and 1564 cm –1 , originating from the C–C in-ring stretching and the conjugative backbone CC–C ring stretching of PPy, , respectively. In addition, it can be found that the characteristic peaks of Fe 2 O 3 are significantly weakened, which is due to the complete encapsulation of Fe 2 O 3 NFs within the PPy sheaths.…”

Poly(3,4‐ethylenedioxythiophene):Poly(styrene sulfonate) in antibacterial, tissue engineering and biosensors applications: Progress, challenges and perspectives

“…34 Also, enhancement in antibacterial properties of PPy synthesized via chemical polymerization of pyrrole in the presence of acriflavine hydrochloride dye was reported. 46 Further, the antimicrobial activities of PPy or PANI coated fabrics with the help of Ag nanoparticles and PPy aerogels in composition with the cellulose were demonstrated. 47,48 Similarly, functionalized polyaniline was examined for the antibacterial properties against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) bacteria as reported by Robertson et al 49 They proposed that via hydrogen peroxide production, hydroxyl radicals formation take place which can be responsible for perturbing bacterial cell growth.…”

“…For instance, a composite of PPy with dextrin exhibited antibacterial activity against the gram‐positive and gram‐negative bacteria 34 . Also, enhancement in antibacterial properties of PPy synthesized via chemical polymerization of pyrrole in the presence of acriflavine hydrochloride dye was reported 46 . Further, the antimicrobial activities of PPy or PANI coated fabrics with the help of Ag nanoparticles and PPy aerogels in composition with the cellulose were demonstrated 47,48 .…”