Two cases of dermatomyofibroma (plaque‐like dermal fibromatosis)

Gómez-Moyano, Elísabeth; Vera-Casaño, Ángel; Martínez-García, S.; Sánz-Trelles, A.; Crespo-Erchiga, Vicente

doi:10.1111/j.1365-4632.2010.04471.x

Cited by 18 publications

(12 citation statements)

References 14 publications

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“…In the 34 reported pediatric dermatomyofibromas, including our cases (Tables 1 and 2), the youngest patient was 11 months old at diagnosis, 14 although in one case the mother stated that the lesion was present at birth 11 and in another one, since the child was 2 months old 14 . Therefore, the existence of congenital dermatomyofibroma cannot be excluded.…”

Section: Discussionmentioning

confidence: 74%

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Dermatomyofibromas presenting in pediatric patients: clinicopathologic characteristics and differential diagnosis

Tardío

Azorín

Hernández‐Núñez

et al. 2011

Journal of Cutaneous Pathology

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Dermatomyofibroma represents a rare benign fibroblastic/ myofibroblastic cutaneous tumor that mostly occurs in young adult women. It has been seldom reported in pediatric patients. In this analysis, the clinical, histopathological and immunohistochemical findings of 12 dermatomyofibromas occurring in patients up to 16 years of age are compared with those reported in adults. Six patients were male and six were female. Nine lesions were located on the neck, two on the back and one involved the chest. The usual presentation was as an asymptomatic plaque composed of bland spindled cells arranged in dermal fascicles that were oriented parallel to the epidermis. Immunohistochemically, the lesional cells expressed calponin in 11 cases, smooth muscle actin in six and muscle-specific actin in three. In contrast to prior reports from adults, dermatomyofibromas in pediatric patients do not show a female predilection. In addition, they are mostly located on the neck (56%), while in adults the most frequent location is the shoulder (35%). Dermatomyofibromas seem to stabilize after an initial period of enlargement. Punch biopsy and clinical follow up could be an alternative approach to the surgical excision in some cases of dermatomyofibroma, particularly in instances in which surgery might inflict cosmetic defects.

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Section: Discussionmentioning

confidence: 74%

“…Dermatomyofibroma has been seldom described in pediatric patients. In our review of the international literature, we found only 22 cases, all of which were published as case reports or included in series with adult patients 1–14 . In one third of the reported cases, only limited information was available 2,13 …”

mentioning

confidence: 99%

Dermatomyofibromas presenting in pediatric patients: clinicopathologic characteristics and differential diagnosis

Tardío

Azorín

Hernández‐Núñez

et al. 2011

Journal of Cutaneous Pathology

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“…Surgical excision is the treatment of choice with a low relapse rate even after incomplete excision (Gill, Arlette, Shiau, & Abi Daoud, ; Hügel, ; Mentzel & Kutzner, ). Most common single lesions are observed by multiple lesions have been described in rare cases (Campagnolo et al, ; Cano Martínez, Fernández‐Antón Martínez, Barchino Ortiz, Lecona Echevarría, & Campos Domínguez, ; Gomez‐Moyano, Vera‐Casaño, Martinez‐Garcia, Sanz‐Trelles, & Crespo‐Erchiga, ; Guillen & Requena, ; Hügel, ; Ma, Wieland, & Tollefson, ; Macedo, Mann, Zimmerman, Alves Mde, & Daxbacher, ; Mentzel & Kutzner, ; Romaní, Leal, Sáez, & Luelmo, ; Tardío et al, ; Viglizzo, Occella, Calonje, Nozza, & Rongioletti, ).…”

Section: Discussionmentioning

confidence: 99%

Dermatomyofibroma—A rare mesenchymal tumor with maintained horripilation

Wollina

Schönlebe

2019

Dermatologic Therapy

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Dermatomyofibroma is a rare mesenchymal tumor of skin. The major differential diagnosis is dermatofibrosarcoma protuberans. Both lesions are composed of spindle‐shaped cells which are CD34‐positive. In contrast to the malignant counterpart, the tumor cells in dermatomyofibroma are without any evidence of COL1A1‐PDGFB gene rearrangement. We present a case of axillary dermatomyofibroma in a 31‐year‐old woman. A hitherto undescribed clinical phenomenon is a maintained horripilation in contrast to dermatofibrosarcoma protuberans.

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“…Dermatomyofibroma is an uncommon benign cutaneous tumor with fibroblastic and myofibroblastic differentiation . It is mainly found in young women and is usually located on the shoulder and adjacent regions, with only a few cases reported in males .…”

Section: Discussionmentioning

confidence: 99%