Two cases of Kawasaki disease presented with acute febrile jaundice

Kaman, Ayşe; Aydın-Teke, Türkan; Gayretli-Aydın, Zeynep Gökçe; Öz, Fatma Nur; Metin-Akcan, Özge; Eriş, Deniz; Tanır, Gönül

doi:10.24953/turkjped.2017.01.015

Cited by 8 publications

(6 citation statements)

References 7 publications

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“…This case and others emphasize the importance for emergency physicians to retain a high level of suspicion for KD when a child presents with febrile or afebrile obstructive jaundice. [7][8][9][10][11][12][13][14][15] Documented patient informed consent and/or Institutional Review Board approval has been obtained and filed for publication of this case report.…”

Section: Discussionmentioning

confidence: 99%

“…We identified nine previous case reports, with a total of 17 KD patients displaying jaundice. [7][8][9][10][11][12][13][14][15] Although rarely reported, KD is the most common cause of glutamyltransferase was elevated at 241U/L (15-73 U/L). Throat cultures, antistreptolysin O, hepatitis B surface antigen, hepatitis B core antibody, hepatitis A immunoglobulin (Ig) M, hepatitis C antibody, cytolomegalo virus IgG/IgM, toxoplasmosis IgG/IgM, monospot, blood cultures, and leptospirosis testing were negative, making infectious or post-infectious etiologies less likely.…”

Section: Image 1 Erythematous Tongue With Papules On Day Of Emergency Department Presentation (Day 4 Of Illness)mentioning

confidence: 99%

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Acute Jaundice in a Six-year-old: An Unusual Presentation of Atypical Kawasaki Disease

Bylund

Zarow

Ponce

2020

Clinical Practice and Cases in Emergency Medicine

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Kawasaki disease (KD) is a rare vasculitis of childhood that is critical to recognize and treat due to associated morbidity and mortality. A six-year-old male presented to our emergency department (ED) afebrile but with reported recent fevers. Exam revealed jaundice and erythematous tongue with papules, and laboratory studies indicated a direct hyperbilirubinemia. Admitted for evaluation, he developed continuous fever, increasing maculopapular rash, and subsequent desquamation of hands and feet. He ultimately met criteria for incomplete KD, was treated with intravenous immunoglobulin, and avoided cardiac complications. This presentation of incomplete KD with hyperbilirubinemia is rare because the patient was afebrile at ED presentation.

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Section: Discussionmentioning

confidence: 99%

Section: Image 1 Erythematous Tongue With Papules On Day Of Emergency Department Presentation (Day 4 Of Illness)mentioning

confidence: 99%

Acute Jaundice in a Six-year-old: An Unusual Presentation of Atypical Kawasaki Disease

Bylund

Zarow

Ponce

2020

Clinical Practice and Cases in Emergency Medicine

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“…KD may present with uncommon symptoms such as pneumonia, pleural effusion, diarrhea, vomiting, sterile pyuria, gallbladder hydrops, acute cholestatic hepatitis, arthritis, and aseptic meningitis [2–7]. Pulmonary system involvement of KD is very rare; KD can present as pneumonia, pulmonary nodules, bronchopneumonia, hydropneumothorax, and pleural effusion [6, 8, 9].…”

Section: Discussionmentioning

confidence: 99%

Pleural effusion as an atypical presentation of Kawasaki disease: a case report and review of the literature

et al. 2019

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BackgroundKawasaki disease is an acute, febrile vasculitis of childhood that affects medium-sized arteries, predominantly the coronary arteries. It is a multisystem disease; therefore, it may present with non-cardiac findings of disease.Case presentationHere, we report the case of 7-year-old Turkish girl who presented with symptoms of fever, chest pain, and vomiting, who was diagnosed as having Kawasaki disease. We also present a literature review on pulmonary involvement due to Kawasaki disease.ConclusionPediatricians should consider the diagnosis of Kawasaki disease in the presence of pneumonia and pleural effusion that is nonresponsive to antibiotic therapy. This will prevent delay in diagnosis and the adverse consequences of the disease.

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“…However, in another study of 23 patients, hydrops of gallblader was reported in 1 case and transaminase elevation in 7 cases [ 7 ]. Kaman et al also reported 2 cases of atypical kawasaki disease with acute febrile jaundice [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

An Unusual Presentation of Kawasaki Disease: Gallbladder Hydrops and Acute Cholestatic Hepatitis

Kilic

Baysun

Gökşen

et al. 2018

Case Reports in Medicine

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Kawasaki disease is the most common vasculitis of childhood. In its classical form, at least four of five diagnostic criteria including cervical lymphadenopathy (1.5 cm or more), nonsuppurative conjunctivitis, intraoral mucosal changes, edema in hands and feet, and maculopapular rash are required with prolonged fever over 5 days. Atypical cases which are different from the classical type or incomplete cases which does not include all the diagnostic criteria can be seen. The typical Kawasaki disease is a self-limiting disease with fever lasting for an average of two weeks. In such patients who have not been diagnosed and whose treatment has been delayed, coronary artery aneurysm, myocardial depression, arrhythmia, and vascular complications may increase morbidity and mortality. We would like to present a rare case of an atypical patient with gallbladder hydrops and acute cholestatic hepatitis.

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Two cases of Kawasaki disease presented with acute febrile jaundice

Cited by 8 publications

References 7 publications

Acute Jaundice in a Six-year-old: An Unusual Presentation of Atypical Kawasaki Disease

Acute Jaundice in a Six-year-old: An Unusual Presentation of Atypical Kawasaki Disease

Pleural effusion as an atypical presentation of Kawasaki disease: a case report and review of the literature

An Unusual Presentation of Kawasaki Disease: Gallbladder Hydrops and Acute Cholestatic Hepatitis

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