Two Cases of Neuroendocrine Tumor of the Testis

Abstract

Journal of Urology and Nephrology Open Access Open Access Case Report orchiectomy, which microscopically revealed a well differentiated neuroendocrine tumor confined to the testis and epididymis with no lymph vascular invasion. No other teratomatous elements or germ cell components were identified. Immunohistochemistry showed the tumor cells to be positive for chromogranin and CK(MNF) while negative for inhibit, calretinin and melan-A. Ki-67 proliferative index is 3-4% (Figure 1). An extra testicular carcinoid tumor was ruled out and the tumor was staged as pT1NxMx. After two years of follow up with cross sectional imaging and tumor markers including chromogranin A and 5-Hydroxyindoleacetic Acid, no recurrence has been documented and the patient is doing well. Case 2 A 40-year-old male patient, not known to have previous illnesses, who presented with a progressive, painless left testicular swelling, he denied any weight loss, trauma, hematuria or systemic symptoms. On physical examination a hard mass was palpable on the left testis. Upon admission his hemoglobin was 13.6 g/dl, white blood cell count 7.4 10'3/µL, and Creatinine 1.0, electrolytes and liver function test values were within normal range. He had a body mass index of 26 kg/m2.He had ultrasound imaging which showed a mass of about 5cm associated with hydrocele (figure 2,3).