Two cases of syphilitic cervical lymphadenitis with a hard chancre at the angle of the mouth

Ueno, Yoshio; Jinbu, Yoshinori; Miyagi, Norito; Kusama, Mikio

doi:10.5794/jjoms.53.486

Cited by 5 publications

(1 citation statement)

References 2 publications

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“…Treponemal tests, used to confirm a diagnosis, include the passive agglutination method TPHA and the indirect fluorescent antibody method FTA-ABS. 11 As the findings for the present patient included an RPR result of 1+, a TP antibody assay result of 1+, and an FTA-ABS result of 2+, the diagnosis was determined to be syphilis.…”

Section: Discussionmentioning

confidence: 75%

A case of secondary syphilis presenting on the oral mucosa: A case report

Harada

Amekawa

Takubo

et al. 2019

Oral Science International

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Syphilis is a sexually transmitted disease caused by Treponema pallidum. We report a case of secondary syphilis originating in the oral mucosa. The patient was a 58‐year‐old man who visited our hospital at May 2009. Clinical examination revealed a mass at the right angle of the mouth with a white mass on the tip of the tongue and an indurated ulcer on the left border of the tongue. Magnetic resonance imaging revealed multiple swollen lymph nodes in the bilateral submandibular glands, as well as in the bilateral deep cervical and supraclavicular lymph nodes. Serological examination revealed elevated rapid plasma reagin (RPR) (titer, 1:32) and Fluorescent treponemal antibody absorption test (2+) values. Consequently, the mass at the right angle of the mouth, the white patch on the tip of the tongue, and the ulcer on the left border of the tongue were diagnosed as secondary syphilis. Oral amoxicillin 1500 mg/d was administered for 4 weeks. The oral lesions improved after 20 days of treatment and the RPR titer had improved to 1:2 after 5 months of treatment.

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Section: Discussionmentioning

confidence: 75%

A case of secondary syphilis presenting on the oral mucosa: A case report

Harada

Amekawa

Takubo

et al. 2019

Oral Science International

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Primary Syphilis with Initial Lower-lip Sclerosis-A Case Report

Omura

Fukuoka²,

Suzuki³

2010

Nippon Jibiinkoka Gakkai Kaiho

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We report a case of primary syphilis with initial lower−lip sclerosis. 54−year−old man seen for a left lower−lip lesion was found in serological testing to have elevated syphilis−rapid plasma regain STS−RPR and treponema pallidum lipid antigen TPLA , diagnosed as primary syphilis. Following four weeks of 1500 mg/day amoxicillin administration, the lesion had almost disappeared. Serological data had improved to within the negative range six months after antibiotic treatment started. This case underscores the need to recognize syphilis of the lip even in the outpatient setting.

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Otorhinolaryngological Manifestations of Syphilis: Report of Seven Cases

Aruga

Takimoto

Kitamura

et al. 2021

Nippon Jibiinkoka Tokeibugeka Gakkai Kaiho(Tokyo)

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Recently, syphilis has become a major public health problem in Japan. We report seven cases of syphilis that were encountered in the otorhinolaryngology department at the Osaka Police Hospital over a period of one year and five months. Five of the seven patients were diagnosed as having pharyngeal syphilis. The butterfly appearance, one of the characteristic findings of pharyngeal syphilis, was found in two patients. Four patients had cervical lymphadenopathy, and three of them did not have any cervical tenderness. One of these four patients presented with only cervical lymphadenopathy, with no associated pharyngeal findings, and was diagnosed as a case of syphilitic cervical lymphadenopathy.Evidence of neurosyphilis was found in four of the seven patients. Vestibular dysfunction was found in two patients, and facial palsy in one. The findings of pharyngeal syphilis disappeared rapidly after treatment. Thus, as the condition is eminently treatable, otolaryngologists should make an early and appropriate diagnosis of syphilis. Proactive cerebrospinal fluid examination and neurological examinations may be needed to rule out the possibility of asymptomatic neurosyphilis.

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Two cases of syphilitic cervical lymphadenitis with a hard chancre at the angle of the mouth

Cited by 5 publications

References 2 publications

A case of secondary syphilis presenting on the oral mucosa: A case report

A case of secondary syphilis presenting on the oral mucosa: A case report

Primary Syphilis with Initial Lower-lip Sclerosis-A Case Report

Otorhinolaryngological Manifestations of Syphilis: Report of Seven Cases

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