Two Cases of Tinea Corporis by Infection from a Rabbit with Arthroderma benhamiae.

Kawasaki, Masanori; Aso, Miki; Inoue, Taeko; Ohsawa, Tokuya; Ishioka, Sakae; Mochizuki, Takashi; Ishizaki, Hiroshi

doi:10.3314/jjmm.41.263

Cited by 21 publications

(16 citation statements)

References 6 publications

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“…The species was not isolated in Japan in an intensive mating study performed in 1980 (3), and the first reported case in Japan was a dermatophytosis on a rabbit in 1997 (4). After that, several cases of dermatophytoses on humans have been reported, but all these cases were infected by pet animals (5‐7). We report a Japanese patient with A. benhamiae infection who had no contact with any infected animals but became infected while conducting research on this dermatophyte.…”

Section: Introductionmentioning

confidence: 99%

A Japanese Case of Tinea Corporis Caused by Arthroderma benhamiae

Mochizuki

Watanabe

Kawasaki

et al. 2002

The Journal of Dermatology

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We report a case of tinea corporis in Japan caused by Arthroderma benhamiae. A 53-year-old female scientist, who had been working on dermatophytes in a laboratory, noticed pruritic erythema on the outer corner of her left lower eyelid. She used a steroid ointment for three days, but the lesion continued to expand. When she visited our clinic, the erythema was 15 mm in diameter and clearly demarcated with a slightly depressed center. A scale from the periphery of the erythema was positive with direct KOH examination, and T mentagrophytes was isolated from the lesion. The erythema was successfully treated with topical application of butenafine hydrochloride. The isolate was mated with a (+) strain of the Americano-European race of A. benhamiae. Using the most sensitive molecular typing method, restriction exzyme analysis of the non-transcribed spacer region of the ribosomal DNA, the restriction profile of the isolate was the same as that of strains used in her laboratory but different from those of any Japanese isolates associated with pet animals. The results suggest that the patient became infected during her experiment.

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Section: Introductionmentioning

confidence: 99%

A Japanese Case of Tinea Corporis Caused by Arthroderma benhamiae

Mochizuki

Watanabe

Kawasaki

et al. 2002

The Journal of Dermatology

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“…The present molecular epidemiological study showed consistency in the NTS types between the strains isolated from different lesions in the same patients, between the strains isolated from members of the same family, and between the strains isolated from pets and their owners (Table 1). For example, strains isolated from an owner (KMU4136) (6) and from her pet rabbit (KMU4137) (6) were of the NTS1 type, and 2 strains isolated from different lesions in 1 patient (KMU4169 and KMU4170) (19) were of the NTS8 type. Moreover, the NTS1, NTS2, and NTS8 strains were isolated from geographically distant areas of Japan (Fig.…”

Section: Structure Of the Nts Regionsmentioning

confidence: 99%

“…However, in 1997, the first isolates of A. benhamiae were cultured from a rabbit in Japan (5). The strains isolated from a family with human dermatophytosis and their household pet (a rabbit) in 1996 were later identified as A. benhamiae strains (6). Several isolates of A. benhamiae have since been cultured from human and animal specimens in Japan, and the origins of these strains and the pathway of their dissemination are of epidemiological interest.…”

Section: Introductionmentioning

confidence: 99%

Molecular Epidemiology of a Major Subgroup of Arthroderma benhamiae Isolated in Japan by Restriction Fragment Length Polymorphism Analysis of the Non-Transcribed Spacer Region of Ribosomal RNA Gene

et al. 2012

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SUMMARY: Arthroderma benhamiae vectored by small animals, such as household pets, causes tinea lesions on human skin. The number of tinea cases caused by this species is increasing in Japan. We attempted to develop a simple molecular method for strain discrimination, which is expected to be useful in molecular epidemiology. Out of the 61 strains of A. benhamiae registered at our institute, 46 A. benhamiae strains showed very high degrees of sequence similarity on cluster analysis of the internal transcribed spacer regions of ribosomal RNA (rRNA) genes. These 46 strains, including 22 strains isolated from Japan, were further used for strain typing by analyzing the non-transcribed spacer (NTS) region of the rRNA gene. Polymerase chain reaction was performed using a primer pair designed for amplification of a part of the NTS region, and the amplicons were successfully discriminated by restriction fragment length polymorphism (RFLP) analysis performed using MvaI. RFLP analysis showed 11 NTS types (NTS1-NTS11) among the 46 strains. Out of the 22 Japanese strains, 10 were of the NTS8 type; 6, of the NTS1 type; 3, of the NTS2 type; and 3, of the NTS5 type. Molecular typing showed consistency of NTS types among the strains isolated from different lesions on the same patient, among the strains derived from the same family, and among the strains from pets and their owners. We observed that 3 out of the 4 NTS types among the Japanese strains were detected outside Japan as well.

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“…Isoliert wurde hier zumeist T. mentagrophytes (39,45), aber auch Microsporum (M.) canis (7,33,43) und in selteneren Fällen M. gypseum (23,34,44). Bei den wenigen Berichten zu Dermatophytosen bei Haustierkaninchen handelt es sich häufig um Fallberichte von Einzeltieren (22,32,34,44,45). Eine Vielzahl von Faktoren werden als begünstigend für die Entwicklung einer Dermatophytose bei Kaninchen diskutiert (8,15), Studien zur Dermatophytose bei Haustierkaninchen gibt es aber nicht.…”

Section: Introductionunclassified

Risikofaktoren, klinisches Bild, Therapie und Zoonoserisiko bei Kaninchen mit Dermatophytose

Kramer¹,

Müller²,

Hein³

2012

Tierarztl Prax Ausg K

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ZusammenfassungZielder Studie war die Auswertung von Angaben zu Umgebung, klinischem Bild und Therapie von Haustier-Kaninchen mit Dermatophytose und die Ermittlung des von ihnen ausgehenden Zoonoserisikos. Material und Methoden: Bei positivem Dermatophytenbefund im Labor wurde ein Fragebogen an den Tierarzt verschickt, der einen Fragenteil für ihn selbst sowie einen für den Besitzer enthielt. Zur Auswertung gelangten 11 von Tierarzt und Besitzer beantwortete Fragebögen sowie acht nur vom Tierarzt ausgefüllte Fragebögen. Erfragt wurden Daten zur Umgebung der Tiere (Herkunft, Haltung, Fütterung, Gruppengröße, Neuzugänge, Veränderungen), zu klinischen Symptomen, Diagnose, Therapie und Zoonosefällen. Ergebnisse: Am häufigsten ließ sich Trichophyton (T.) mentagrophytes (m.) isolieren (15/19). Die Hälfte betroffener Tiere war jünger als 5 Monate und es waren doppelt so viele weibliche wie männliche Kaninchen vertreten. In vier von 11 Fällen gab es in den Wochen vor dem Dermatophytoseausbruch einen Neuzugang und in sieben von 11 Fällen befanden sich die betroffenen Tiere nicht länger als 3 Monate im Haushalt. Die vorherrschende Gruppengröße war zwei Tiere und in der Hälfte der Fälle war auch das Partnerkaninchen betroffen. Die Tiere zeigten meist alopezische Hautveränderungen mit Schuppen und/oder Krusten, die besonders häufig am Kopf (16/19) und dort in der Hälfte der Fälle an den Ohren auftraten. In drei von 11 Fällen (27,3%) wiesen Kinder in der Familie Hautveränderungen auf (Hände, Gesicht, Schulter). Schlussfolgerung: Als Haustier gehaltene Kaninchen mit Dermatophytose stellen ein nicht zu unterschätzendes Zoonoserisiko für ihre Besitzer, vor allem für Kinder dar. Risikofaktoren scheinen dabei die Ankunft eines neuen Tieres und ein junges Alter der Kaninchen zu sein. Klinische Relevanz: Bei Kaninchen mit alopezischen Hautveränderungen mit Schuppen und/oder Krusten, vor allem am Kopf, sollte eine Dermatophyteninfektion ausgeschlossen werden. Eine ausreichende Aufklärung der Besitzer über das Zoonoserisiko ist unerlässlich, besonders wenn sich Kinder im Haushalt befinden.

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Two Cases of Tinea Corporis by Infection from a Rabbit with Arthroderma benhamiae.

Cited by 21 publications

References 6 publications

A Japanese Case of Tinea Corporis Caused by Arthroderma benhamiae

A Japanese Case of Tinea Corporis Caused by Arthroderma benhamiae

Molecular Epidemiology of a Major Subgroup of Arthroderma benhamiae Isolated in Japan by Restriction Fragment Length Polymorphism Analysis of the Non-Transcribed Spacer Region of Ribosomal RNA Gene

Risikofaktoren, klinisches Bild, Therapie und Zoonoserisiko bei Kaninchen mit Dermatophytose

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