Two‐Dimensional Nitrogen‐Doped Ti₃C₂ Promoted Catalysis Performance of Silver Nanozyme for Ultrasensitive Detection of Hydrogen Peroxide

Abstract

Silver nanoparticles (AgNPs)-based nanozyme sensors are gaining attention for rapid on-site H 2 O 2 detection, which is beneficial to disease diagnosis and environmental monitoring. However, the severe agglomeration of AgNPs on the electrodes significantly reduced electrochemical catalytic activity. In this work, we fabricated N-doped Ti 3 C 2 MXene (named Ag/NÀ Ti 3 C 2 ) deposited with three-dimensional flower-like AgNPs to achieve ultrasensitive H 2 O 2 detection. N doping strategy is employed to improve the conductivity of MXene, and the corresponding catalytic activity of Ag/NÀ Ti 3 C 2 is enhanced by optimizing the growth process and morphology. The Ag/NÀ Ti 3 C 2 /glassy carbon electrode (Ag/N-Ti 3 C 2 /GCE) sensor exhibited a wide H 2 O 2 detection range (0.05-35 mM), a low limit detection (1.53 μM), and 3.1 % relative standard deviation in 50 repeated cyclic voltammetry measurements. The results above indicate that catalytic activity of metal nanozymes could be influenced by the substrate and both materials jointly determine the sensor's performance. As a result, N-doped MXene is an attractive candidate for biological sensing and other electrocatalytic applications.

Advancements in Photothermal Therapy Using Near-Infrared Light for Bone Tumors

“…In the realm of metal-based nano-ions, their loading onto a PTA for a synergistic PTT/CDT effect is a widely explored avenue. Notably, materials such as polydopamine (PDA), porous carbons, metal-organic frameworks, and transition metal carbide (MXene) feature prominently in these studies [128]. PDA nanomaterials have been widely explored as carriers to enhance the drug inhibition of tumor cells under near-infrared (NIR) irradiation [129].…”

RhRu Alloy‐Anchored MXene Nanozyme for Synergistic Osteosarcoma Therapy

“…[ 30 ] Furthermore, anchoring nanozyme on effective carriers, such as porous carbons, metal organic framework, transition metal carbide (MXene), and so on, was proven effective to improve the catalytic activity because of the electronic interaction between nanozyme and carriers. [ 31–33 ] Among various carriers, MXene exhibits satisfactory hydrophilicity and biocompatibility, abundant functional groups, and high electron conductivity, [ 34 ] which has been used as a promising carrier for nanozymes. Zhu et al.…”

“…[30] Furthermore, anchoring nanozyme on effective carriers, such as porous carbons, metal organic framework, transition metal carbide (MXene), and so on, was proven effective to improve the catalytic activity because of the electronic interaction between nanozyme and carriers. [31][32][33] Among various carriers, MXene exhibits satisfactory hydrophilicity and biocompatibility, abundant functional groups, and high electron conductivity, [34] which has been used as a promising carrier for nanozymes. Zhu et al decorated Pt nanozymes with POD-like activity on the Ti 3 C 2 nanosheets, and found the rise in temperature caused by photothermal effect of the nanocomposite can significantly enhance the nanozymatic activity, thereby realizing satisfactory synergistic treatment of PTT/CDT therapy.…”

Enhancement of MXene optical properties towards medical applications via metal oxide incorporation

“…10 Many experimental and theoretical studies 20 explored the stupendous potential of MXenes for various applications in optoelectronics, photonics, catalysis, and many other areas. 19,21 MXenes emerge as new 2D nanoplatforms for advanced optoelectronics to be explored in various biomedical applications like biosensing, 22 bioimaging, 23 and therapeutic applications. 24,25 The essential mechanical and electronic properties can be attained by tailoring the elemental composition and chemical functionalization.…”