Two new triterpenoid saponins from the underground parts of Weigela x “Bristol Ruby”

Saponins of Selected Triterpenoids as Potential Therapeutic Agents: A Review

“…Other oleanane-type saponins 3a and 3b ( Figure 3 ) were isolated from plants of the genus Weigela Thunb. (Caprifoliaceae) [ 36 ] that is composed of about ten species, mainly distributed in Asia, but can be found in Europe as well [ 37 ]. Over 200 cultivars have been produced for ornamental purposes [ 36 , 37 ].…”

“…(Caprifoliaceae) [ 36 ] that is composed of about ten species, mainly distributed in Asia, but can be found in Europe as well [ 37 ]. Over 200 cultivars have been produced for ornamental purposes [ 36 , 37 ]. The oleanane saponins were generally reported to possess a spectrum of pharmacological activities that include anti-inflammatory [ 38 ], anticomplementary [ 39 ], stimulatory [ 40 ] and cytotoxic activity [ 37 , 41 , 42 , 43 ].…”

“…They are also capable of recognizing antibodies [ 44 ]. A detailed study with 3a and 3b has not yet been published [ 36 ]; however, based on the investigation performed by other authors [ 45 ], it is supposed that the important pharmacological potential of 3a and 3b will be evaluated later on.…”