Two rhodamine-azo based fluorescent probes for recognition of trivalent metal ions: crystal structure elucidation and biological applications

Abstract

Two rhodamine and azo based chemosensors, (HL1 =(3',6'-bis(ethylamino)-2-((-2-hydroxy-3-methoxy-5-(phenyldiazenyl)benzylidene)amino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one) and HL2= (3',6'-bis(ethylamino)-2-(((2-hydroxy-3-methoxy-5-(p-tolyldiazenyl)benzylidene)amino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one) have been synthesized for colorimetric and fluorometric detection of three trivalent metal ions, Al3+, Cr3+ and Fe3+. The chemosensors...

Regenerable and Highly Stable Two-Dimensional Imine-Based Covalent Organic Framework for Simultaneous Rapid Detection and Adsorption of Cu2+ Ions

“…Metal ion recognition plays a crucial role in various fields, including environmental monitoring, biological sensing, and separation science. − Among several metal ion recognitions, copper ion (Cu 2+ ) recognition has garnered significant attention due to its importance in human health and environmental issues. − Concretely, Cu 2+ deficiency can cause osteoporosis, while Cu 2+ accumulation can lead to serious health problems such as liver damage, neurodegenerative diseases, and oxidative stress. − The release of Cu 2+ into the environment during mining, production, utilization, and reprocessing poses a substantial threat to water systems, ecological security, and human health, driven by advancements in industry and agriculture . Therefore, it is of utmost importance to develop efficient methods for the selective recognition, detection, and removal of Cu 2+ .…”

Structure–metal ion selectivity of rhodamine-based chemosensors

“…Mandal and co-workers recently synthesized two probes ( 18a and 18b ) (Scheme 2) like the structure of 17 with two differences. 33 These compounds are based on rhodamine 6G fluorophore and H or CH 3 is present in place of the nitro group. A peak was generated at 525 nm in the absorption spectra of 18a or 18b in the presence of Al 3+ , Fe 3+ and Cr 3+ in Britton–Robinson buffer solution, pH 7.4 (1 : 9, water : methanol, v/v).…”

Aza-phenol Based Macrocyclic Probes Design for “CHEF-on” Multi Analytes Sensor: Crystal Structure Elucidation and Application in Biological Cell Imaging

“…In this context, we are mainly concentrating on chemosensor which can detect Zn 2+ , Al 3+ , Cr 3+ and Fe 3+ ions. − Iron and zinc are the first and second most abundant transition metals present in human body . In many biochemical processes, both iron and zinc play essential role to complete the biocycle.…”