Two-Stage Screening Designs Applied to Chemical-Screening Problems With Binary Data

Rm, Elashoff

doi:10.1146/annurev.bb.05.060176.003021

Annu. Rev. Biophys. Bioeng.

1976

DOI: 10.1146/annurev.bb.05.060176.003021

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Two-Stage Screening Designs Applied to Chemical-Screening Problems With Binary Data

Elashoff Rm¹

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Cited by 4 publications

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A 2‐step procedure for comparing binomial populations available when given differences are to find out

Kanka¹

1981

Biometrical J

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A two-step procedure for comparing two binomial probabilities is presented. The method is compared with the exact test of FISHER. In average it needs essentially smaller sample sizes. I n situations like drug screening it is desired to minimize the type I1 error rates for great differences of the binomial probabilities and to maximize it for small differences, simultaneously. In this point the method is superior to'the FISHER test. Examplea from drug screening demonstrate the advantages of the method.

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A 2‐step procedure for comparing binomial populations available when given differences are to find out

Kanka¹

1981

Biometrical J

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An efficient multiple-stage procedure for phase II clinical trials that have high response rate objectives

Chen

Soong

Wheeler

1994

Controlled Clinical Trials

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A survey of two stage tests of hypotheses: theory and application

Hewett

Spurrier

1983

Communications in Statistics - Theory and Methods

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Two-Stage Screening Designs Applied to Chemical-Screening Problems With Binary Data

Cited by 4 publications

References 12 publications

A 2‐step procedure for comparing binomial populations available when given differences are to find out

A 2‐step procedure for comparing binomial populations available when given differences are to find out

An efficient multiple-stage procedure for phase II clinical trials that have high response rate objectives

A survey of two stage tests of hypotheses: theory and application

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