Types and subtypes of haptoglobin in the Chinese population

Chen, Liang; Qi, Zhi; Ying, Qiao; Wang, L F

doi:10.1007/bf00291540

Cited by 8 publications

(5 citation statements)

References 9 publications

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“…21 In contrast, the frequency of the 1 to 1 phenotype has been found to be lower in Asian populations, while the frequency of 2 to 2 is higher. 1,10,22 The findings from the current study regarding phenotype distribution are in agreement with those previously reported.…”

Section: Discussionsupporting

confidence: 96%

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Haptoglobin phenotypes and plasma haptoglobin levels in patients with abdominal aortic aneurysm

Pan

Cheng

Shih

et al. 2011

Journal of Vascular Surgery

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Section: Discussionsupporting

confidence: 96%

“…1 In normal aortas, the lamellar structure of media is the thickest layer and is an orderly array of collagen, elastin, and smooth muscle cells. Degeneration of this matrix leads to destruction of the media and adventia, which in turn results in gradual aortic dilation.…”

mentioning

confidence: 99%

Haptoglobin phenotypes and plasma haptoglobin levels in patients with abdominal aortic aneurysm

Pan

Cheng

Shih

et al. 2011

Journal of Vascular Surgery

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“…The Chinese of Hong Kong have a higher frequency of Hp' (0.38) (Mourant et al, 1976). Hp' frequency of 0.27 has been reported in the Han Chinese from Beijing and Shanghai, respectively, by Liang et al (1983) and Kong et al (1983). Variable frequencies ofHp' have also been reported in ethnic minorities of China .…”

Section: Haptoglobinmentioning

confidence: 89%

Blood genetic markers in the Chinese of two eastern provinces

Saha

1989

American J Phys Anthropol

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A total of 205 Han Chinese from two eastern provinces (155 from Fujien and 50 from Hopeh) were tested for the distribution of six blood groups--A1A2BO, MN, Rhesus (CcDEe), Lewisa, Kell (Kk) and Fya--four serum proteins--albumin and haptoglobin types; transferrin and group-specific component subtypes--haemoglobin, and twelve red cell enzyme systems--glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, lactate and malate dehydrogenases; acid phosphatase, esterate-D, glyoxalase I, adenylate kinase, glucose-phosphate isomerase, phosphoglucomutase (locus 2), and superoxide dismutase types; and phosphoglucomutase (locus 1) subtypes. The frequencies of blood groups were more or less within the reported frequencies in the Chinese. However the frequency of le was much lower in the present series. The Chinese are characterized by low p1, Ro, k, le, and a high Fya in general. P2 was lacking in the Chinese. There were some differences in the blood group frequencies in the two provinces. The frequencies of Hp alleles; Tf and Gc subtypes show characteristic mongoloid features with high Hp1, TfD, and GcIF. The frequency of TFC2 was higher in the Fujien province than that in Hopeh. At the hemoglobin locus only one Hb AD was detected, while the frequency of the beta-thalassemia trait was 0.03. No red cell G6PD deficiency or variant was detected. The distribution of red cell enzymes showed Mongoloid characteristics with low PGDC, AK2, ESD1, GLO1, and higher pa. PGM1 subtypes also had Mongoloid characteristics with lower PGM2+ and higher PGM2-. The phenotypic distribution of all the fifteen polymorphic loci was at Hardy-Weinberg equilibrium in both the Chinese populations.

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“…Fig ure I shows the frequencies of HP*1 in some Han populations from different regions of China [3][4][5][6]. A significant geographic varia tion can be seen and there is a particular tend ency for the frequency of HP*1 to increase from the north toward the south of China.…”

Section: Methodsmentioning

confidence: 99%

“…Haptoglobin (HP) has been studied in the most parts of the world fl, 2], but so far there is very scanty HP data available on the Chinese population, especially for different ethnic groups within China [3][4][5]. The aim of the present paper is to present data on HP groups in six different ethnic groups in China.…”

Section: Introductionmentioning

confidence: 99%