Types of Filtration

Levy, Richard V.; Jornitz, Maik W.

doi:10.1007/b104242

Cited by 17 publications

(10 citation statements)

References 8 publications

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“…They are stable to heating to 130°C but are sensitive to many solvents. Deep, screened, or mixed retention mechanisms take place in membrane filters, depending on the ratio of pore size to particle size [8]. The rigidity of the support and, thus, the constancy of pore size, and also the mainly sieving mechanism of separation allow membrane filters to be described in terms of some particular pore size [9].…”

Section: Properties and Characteristics Of Materials For Sterilizing mentioning

confidence: 99%

Use of Membrane Filters in Production Technology for Sterile Drugs

et al. 2016

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Filtration is one of the methods on which all the world's chemical-pharmaceutical industries depend. This technological method is used for the sterilization of labile drugs and to provide them with the required properties. As a result of the introduction of strict GMP rules, most current plants use membrane filtration. We review here the main criteria used for selecting material for sterilizing filtration and provide examples of drugs whose manufacture uses this method.

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Section: Properties and Characteristics Of Materials For Sterilizing mentioning

confidence: 99%

Use of Membrane Filters in Production Technology for Sterile Drugs

et al. 2016

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“…It is a promising approach for cell sample preparation. However, it should be noticed that in practical application, the cross-flow filter has to be properly evaluated due to performance differences in dead-volume, shear forces , cleanability, pressure conditions, energy inputs, and flow patterns [3]. Hence, improvement should be carried out for the previous cross-flow microfilter.…”

Section: Materials Andfabricationsmentioning

confidence: 99%

“…2. There being the presence of "dead-end" in the flat membrane filters [3], clogging is inevitable to separate the target cell with smaller dimensions.…”

Section: Clogging Failure Of Membrane-based Microfiltermentioning

confidence: 99%

Clogging failure in microfilter for blood cell separation and its novel improvements

Dong

Yang

Egeland

et al. 2009

2009 16th IEEE International Symposium on the Physical and Failure Analysis of Integrated Circuits

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@hive.no (a) Cross-Flow Filtration (b) Dead-End Filtration Fig. 2 Failure mechanism of filtration without and with dead-end [31.Abstract-Clogging failure is common for microfilter utilizing the flat membrane structure. To reduce clogging failure in microfilters, the turbine blade-like micropillar is introduced in microfilter design. Two improved cross-flow microfilter designs employing the blade-like micropillar barrier are presented, one with varied cross-section channels, and the other with Archimedes' spiral channels. Analogy experimental-data based simulations show that the two aforementioned novel microfilters have good filtrating efficiency and fantastic anti-clogging characteristics. And the commercial value of the turbine blade-like barriers is affirmed by the industry Partners.

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“…Îíè ñòàáèëüíû ïðè íàãðåâàíèè äî 130°C, íî ÷óâñòâèòåëüíû êî ìíîãèì ðàñòâîðèòåëÿì. Â ìåìáðàííûõ ôèëüòðàõ îñóùåñòâëÿåòñÿ â çàâèñèìîñòè îò ñîîòíîøåíèÿ ðàçìåðà ïîð è ðàçìåðà ÷àñòèö ãëóáèííûé, ýêðàííûé èëè ñìåøàííûé ìåõàíèçì óäåðaeèâàíèÿ [8]. Âñëåäñòâèå aeåñòêîñòè êàðêàñà è, ñëåäîâàòåëüíî, íåèç-ìåííîñòè ðàçìåðà ïîð, à òàêaeå áëàãîäàðÿ ïðåèìóùåñò-âåííî ñèòîâîìó ìåõàíèçìó ðàçäåëåíèÿ ìåìáðàííîìó ôèëüòðó ìîaeåò áûòü ïðèïèñàí îïðåäåëåííûé ðàçìåð ïîð [9].…”

Section: ñâîéñòâà è õàðàêòåðèñòèêè ìàòåðèàëîâ äëÿ ñòåðèëèçóþùåé ôèëüòunclassified

Применение Мембранных Фильтров В Технологии Получения Стерильных Лекарственных Препаратов

Гулякин¹,

Николаева²,

Санарова³

et al. 2016

Хим.-фарм. ж.

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Îäíèì èç ìåòîäîâ, áåç êîòîðîãî íå îáõîäèòñÿ íè îäíî èç ñóùåñòâóþùèõ â ìèðå ñîâðåìåííûõ õèìèêî-ôàðìàöåâòè÷åñêèõ ïðîèçâîäñòâ, ÿâëÿåòñÿ ôèëüòðàöèÿ. Äàííûé òåõíîëîãè÷åñêèé ìå-òîä ïðèìåíÿåòñÿ äëÿ ñòåðèëèçàöèè ëàáèëüíûõ ëåêàðñòâåííûõ ïðåïàðàòîâ è ïðèäàíèÿ èì íå-îáõîäèìûõ ñâîéñòâ. Ââåäåíèå ñòðîãèõ ïðàâèë GMP ïðèâåëî ê òîìó, ÷òî â íàñòîÿùåå âðåìÿ âñå ñóùåñòâóþùèå ïðåäïðèÿòèÿ â áîëüøèíñòâå ñëó÷àåâ ðàáîòàþò ñ ìåìáðàííûìè ôèëüòðà-ìè. Â ïðåäñòàâëåííîì îáçîðå ðàññìîòðåíû îñíîâíûå êðèòåðèè, êîòîðûå ïðèìåíÿþòñÿ ïðè âûáîðå ìàòåðèàëà äëÿ ñòåðèëèçóþùåé ôèëüòðàöèè è ïðèâåäåíû ïðèìåðû êîíêðåòíûõ ëåêàð-ñòâåííûõ ïðåïàðàòîâ, ïðè ïðîèçâîäñòâå êîòîðûõ èñïîëüçóåòñÿ äàííûé ìåòîä.Êëþ÷åâûå ñëîâà: ñòåðèëèçóþùàÿ ôèëüòðàöèÿ; ìåìáðàííûå ôèëüòðû; êàñêàäíàÿ ýêñòðó-çèÿ; ëèïîñîìû.

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Types of Filtration

Cited by 17 publications

References 8 publications

Use of Membrane Filters in Production Technology for Sterile Drugs

Use of Membrane Filters in Production Technology for Sterile Drugs

Clogging failure in microfilter for blood cell separation and its novel improvements

Применение Мембранных Фильтров В Технологии Получения Стерильных Лекарственных Препаратов

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