Typification of Chemical Compounds of Marine Sponge Metabolites

Rajendran, I

doi:10.1007/978-81-322-2794-6_11

Cited by 1 publication

(2 citation statements)

References 231 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This can be seen from the association between sponges and bacteria. Bacteria can contribute to host defense by excreting antibiotics and other bioactive substances (Proksch et al 2002;Rajendran, 2016). This creates an opportunity for bioprospecting sponge symbiont bacteria, where the benefits of these symbiotic bacteria need to be explored in order to obtain new biological products.…”

Section: Introductionmentioning

confidence: 99%

“…The term antibiotic comes from the word 'antibiosis' which literally means 'against life'. In the past, antibiotics were considered as organic compounds produced by one microorganism that were toxic to other microorganisms (Rajendran, 2016). As a result of this idea, antibiotics were originally defined broadly as substances, produced by a single microorganism or biological origin.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Antibacterial Activity of Freshwater Sponge Oncosclera asiatica Against Escherichia coli and Staphylococcus aureus

Wulandari

Dewantoro

Lunggani

et al. 2023

Bioma

View full text Add to dashboard Cite

Freshwater sponges are animals from the Porifera phylum that live in freshwater. The sponge used is Oncosclera asiatica was taken from Kali Porong, East Java. Seventeen isolates of bacteria have been obtained from isolation. Antibacterial potential testing was performed by paper disc inhibition assay using Escherichia coli and Staphylococcus aureus as pathogenic bacteria and amoxicillin as a positive control. The antibacterial activity test showed that four isolates have the potential activity. The isolates with the highest inhibition zones were identified using a 16S rRNA.The results of BLAST showed isolate number 2 was Pseudomonas moraviensis with 99.51% similarity. The phylogenetic tree analysis was build using the MEGA X program. The results of the phylogenetic tree analysis showed that P.moraviensis had a bootstrap value of 100% with a genetic distance value of 0.001. P. moraviensis isolates screened for the presence of Non-Ribosomal Peptide Synthetase (NRPS) gene by A2gamF and A3gamR primers. The amplification result from NRPS gene showed positive meaning that P.moraviensis genome contained NRPS gene.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%