“…Al though this connecting link between experiment and clinic [11,29] could be of great help for clinical work, it is often not correctly understood or is underrated. Discussions on this subject have been con tinuing since the end of the forties [5,6,14,16,20,25,34,35,36], Of course, a detailed discussion of methodology is not possible here. We refer to the references at the end of this paper, in which further references are cited.…”