1912
DOI: 10.1515/bchm2.1912.78.3-4.266
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Über den fermentativen Abbau der Cellulose.

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Cited by 92 publications
(19 citation statements)
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“…a, and the second bydrolysing ft lo xylose; the second appears to be more easily inactivated than the first. This interpretation would be in good agreement with the enzymatic hydrolysis of cellulose as sbown by Pringsheim (17,18) and recently confirmed by Levinson, Mandels and Reese (U) by means of the paper chroniatography technique. The cellulose chain is hydrolyzed by cellulase under tbe forma tion of cellobiose, and this again is hydrolyzed to glucose by eellobiase (^-glucosidase).…”
Section: Discussionsupporting
confidence: 88%
“…a, and the second bydrolysing ft lo xylose; the second appears to be more easily inactivated than the first. This interpretation would be in good agreement with the enzymatic hydrolysis of cellulose as sbown by Pringsheim (17,18) and recently confirmed by Levinson, Mandels and Reese (U) by means of the paper chroniatography technique. The cellulose chain is hydrolyzed by cellulase under tbe forma tion of cellobiose, and this again is hydrolyzed to glucose by eellobiase (^-glucosidase).…”
Section: Discussionsupporting
confidence: 88%
“…Interestingly, the German literature at the time referred to cellulose‐degrading enzymes as “celluloselosendes enzyms”, or cellulose‐loosening enzymes (47). From our review of the literature, Pringsheim made the first reference to “cellulases” as enzymes that degrade cellulose in 1912 (48). By the 1920s, evidence was mounting that these enzymes were actually proteins and that proteins were discrete chemical entities.…”
Section: Methodsmentioning
confidence: 99%
“…Pringsheim suggested [14] that one enzyme breaks the long-chain cellulose molecules to short chains (cellobiose), and another enzyme then hydrolyzes cellobiose to glucose. Reese and coworkers [12,15 ] presented evidence that at least two enzymes, C1 1 and Cs, are involved in the breakdown of cellulose to cellobiose, with cellobiase hydrolyzing the latter compound to glucose.…”
Section: Enzyme Activitymentioning
confidence: 99%