Über die Darstellung definiert verzweigter Polysaccharide. II. Einführung von Oligosacchariden als Seitenketten in Amylose und deren Verlängerung durch enzymatische Synthese

Husemann, Von E.; Reinhardt, M.

doi:10.1002/macp.1962.020570109

Cited by 9 publications

(7 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first comb like structures synthesized by enzymatic grafting from polymerization from a polymeric backbone were reported by Husemann et al [24,25] Acetobromo oligosaccharides were covalently bound to 6-trityl-2,3-dicarbanilyl-amylose chains and subsequently elongated by enzymatic polymerization with potato phosphorylase, the result being amylopectin-like structures with various degrees of branching. Pfannemü ller et al extended this work by grafting amylose chains onto starch molecules.…”

Section: Comb-type Copolymers With Amylosementioning

confidence: 97%

Amylose and Amylopectin Hybrid Materials via Enzymatic Pathways

Vlist¹,

Loos²

2007

Macromolecular Symposia

View full text Add to dashboard Cite

Summary: Oligo-and polysaccharides are important macromolecules in living systems, showing their multifunctional characteristics in the construction of cell walls, energy storage, cell recognition and their immune response.Saccharides as organic raw materials can open new perspectives on the way to new biocompatible and biodegradable products which could help to overcome the problems resulting from the upcoming restrictions of petrochemical resources. Construction of well-defined carbohydrate polymer backbones is very challenging as it is difficult to realize complete regio and stereo-control of the glycosylating process. Most synthetic approaches are therefore based on the modification or degradation of naturally occurring polysaccharides resulting in less then perfect products. Enzymes have several remarkable catalytic properties compared with other types of catalysts in terms of their selectivity, high catalytic activity, lack of undesirable side reactions and operation under mild conditions. A biocatalytic pathway to synthesize saccharides is therefore very attractive as it results in well-defined polysaccharides avoiding the above drawbacks.When biogenic polysaccharides are combined with synthetic macromolecules, surfaces etc. materials with new interesting properties arise and the processability of the designed hybrid materials is facilitated. Amylose and amylopectin hybrid materials can be synthesized via enzymatic polymerization routes utilizing transferases. This approach opens access to well-defined hybrid structures bearing amylase or amylopectin moieties that cannot be synthesized by any other means.

show abstract

Section: Comb-type Copolymers With Amylosementioning

confidence: 97%

Amylose and Amylopectin Hybrid Materials via Enzymatic Pathways

Vlist¹,

Loos²

2007

Macromolecular Symposia

View full text Add to dashboard Cite

show abstract

“…Phosphorylase‐catalyzed polymerization is most frequently used for the synthesis of amylose‐grafted polymers. To the best of our best knowledge, the first enzymatically synthesized amylose‐ g ‐polymer was reported by Husemann and Reinhardt in 1962 . They synthesized acetobromo oligosaccharide‐grafted 6‐trityl‐2,3‐dicarbanilylamylose.…”

Section: Enzymatic Synthesis Of Amylose Hybrids By Phosphorylasesmentioning

confidence: 99%

Amylose engineering: phosphorylase‐catalyzed polymerization of functional saccharide primers for glycobiomaterials

Nishimura

Akiyoshi

2016

WIREs Nanomed Nanobiotechnol

View full text Add to dashboard Cite

Interest in amylose and its hybrids has grown over many decades, and a great deal of work has been devoted to developing methods for designing functional amylose hybrids. In this context, phosphorylase‐catalyzed polymerization shows considerable promise as a tool for preparing diverse amylose hybrids. Recently, advances have been made in the chemoenzymatic synthesis and characterization of amylose‐block‐polymers, amylose‐graft‐polymers, amylose‐modified surfaces, hetero‐oligosaccharides, and cellodextrin hybrids. Many of these saccharides provide clear opportunities for advances in biomaterials because of their biocompatibility and biodegradability. Important developments in bioapplications of amylose hybrids have also been made, and such newly developed amylose hybrids will help promote the development of new generations of glyco materials. WIREs Nanomed Nanobiotechnol 2017, 9:e1423. doi: 10.1002/wnan.1423For further resources related to this article, please visit the WIREs website.

show abstract

“…The fi rst comb -like structures synthesized by enzymatic grafting from polymerization from a polymeric backbone were reported by Husemann et al [76,77] . Acetobromo oligosaccharides were covalently bound to 6 -trityl -2,3 -dicarbanilyl -amylose chains and subsequently elongated by enzymatic polymerization with potato phosphorylase, the result being amylopectin -like structures with various degrees of branching.…”

Section: Comb -Type Copolymers With Amylosementioning

confidence: 99%