Sulfuryl chloride is a versatile reagent with great potentialities in organic syntheses. Under appropriate conditions it may be used for the chlorination and sulfonation of both aliphatic and aromatic derivatives. It may also be applied as an acylating and condensing agent. The simplicity of these reactions, their ease of control, and their high yields promise to make the reagent particularly useful in many applications which require simple and unspecialized equipment.