NEITHER the mechanisms underlying the beneficial effects of electric shock therapy nor the factors responsible for some of the untoward results of that procedure are well understood. Pronounced changes in the physiology of the body as a whole occur during convulsions, and it is therefore important to study them. A recent report by Silfverski\l=o"\ld and \l =A%o\mark 1 described changes in venous pressure during electrically induced convulsions in man. It seemed desirable to make a further analysis of the changes observed, and the present report records the results of such a study.
MATERIAL AND METHODSFifty-five determinations were made on 12 patients, who ranged in age from 18 to 59 years; 11 subjects were women. The direct method of Moritz and von Tabora 2 was used. A no. 18 or 19 gage needle was inserted into an antecubital vein, and readings were taken until a base line was reached, usually in two or five minutes. The convulsion was then induced; during and after the convulsion the arm used for the measurements was kept extended by means of manual restraint applied well below the point of insertion of the needle. In only 2 of the 55 experi¬ ments was the needle dislodged from the lumen of the vein during the convulsion. Readings were made every fifteen seconds after the electric shock and were dis¬ continued when a base line was reached or, in a few cases, when the patient went into a state of postconvulsive excitement.