Über Invertseifen I; die Einwirkung von Invertseifen auf Eiweiß‐Stoffe

Kühn, Richard; Bielig, Hans‐Joachim

doi:10.1002/cber.19400731010

Cited by 107 publications

(17 citation statements)

References 15 publications

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“…They are classified as cationic or anionic according to the location of the long-chain, hydrophobic group in the cationic 1 The reader is referred to the paper by Baker, Harrison, and Miller (2) for a relatively complete bibliography of the biological applications of synthetic detergents. In addition, the recent papers by Kuhn and coworkers (3)(4)(5)(6)(7)(8) should be consulted.…”

Section: Methodsmentioning

confidence: 99%

The Bactericidal Action of Synthetic Detergents

Baker

Harrison

Miller

1941

Journal of Experimental Medicine

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1. The bactericidal action of a number of anionic and cationic synthetic detergents on four Gram-positive and three Gram-negative bacteria has been investigated. 2. Cationic detergents, as a group, were found to exhibit marked bactericidal effects on Gram-positive microorganisms and somewhat less pronounced action on Gram-negative organisms. 3. The anionic detergents were germicidal only against the Gram-positive organisms, and they were considerably less effective than the cationic compounds. Of the anionic detergents, the most active one was an alkyl sulfate derived from a branched-chain, secondary alcohol. 4. Correlations between bactericidal action and inhibition of bacterial metabolism, and also between bactericidal action and chemical structure of the detergents are discussed.

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Section: Methodsmentioning

confidence: 99%

The Bactericidal Action of Synthetic Detergents

Baker

Harrison

Miller

1941

Journal of Experimental Medicine

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“…The ability of surfactants to denature and precipitate globular proteins and the disinfecting action of the cationic detergents on bacteria is reported [11,12]. However, it is not possible to generalize about the consequences of interactions of proteins with surfactants due to the diversity of polypeptide structures.…”

Section: Introductionmentioning

confidence: 99%

Interactions of Sodium Dodecyl Benzene Sulfonate and Sodium Dodecyl Sulfate with Gelatin: A Comparison

George¹,

Nair²,

Sreejith³

2007

J Surfact & Detergents

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The interaction of SDS/SDBS in aqueous gelatin solutions is studied above the gelation temperature by viscosity and circular dichroism (CD) measurements. The steep rise observed in the relative viscosity can be due the structural transitions leading to micellar growth of higher order. Circular dichroism spectra indicated that gelatin helped in inducing the sphere?rod transition, without suffering any conformational changes within it. The findings are particularly significant in terms of the head group contribution, hydrophobic interaction and the formation of formulated complexes.

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“…4,5 In 1940, Kuhn and Bielig suggested that quaternary ammonium cations might act on the bacterial membrane. 6 The end result of the interaction between bacteria and a quat is the leakage of intracellular components because of disruption of the membrane functionality. 7,8 There are several soluble quats with strongantibacterial activity reported in literature, but they are highly toxic to the environment as protection from them was short-lived because of the difficulty in controlling the rate of diffusion into the bacteria, besides recontamination problems.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial activity of novel insoluble bead‐shaped polymer‐supported multiquaternary ammonium salts

Murugan

Gopinath

Shanmugayya

et al. 2010

J of Applied Polymer Sci

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This study describes the effect of antibacterial activity of newly reported five different novel insoluble bead-shaped polymer-supported multiquaternary ammonium salts (PM quats) viz., bis-quat, tris-quat (2 Nos.), tetrakis-quat, hexakis-quat containing two, three, four, and six quaternary ammonium groups, respectively. The presence of number of quaternary ammonium groups in each salt was established already through Fourier-transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy, and chloride ion analyzes. The antibacterial activities of these five different PM quats against three different bacteria viz., Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa were investigated by serial dilution and spread plate method and compared the same with a monoquat containing single quaternary ammonium group. The extent of antibacterial activity has been measured in terms of colony forming units (CFU) at different time intervals. The observed results show that all the PM quats exhibited excellent-antibacterial activity against each bacterium. On the basis of the CFU values, the antibacterial activity was found to increase from bis-quat to hexakis-quat, which reveals that the activity of PM quats increases with increase in the number of quaternary ammonium groups. The mechanism of interaction of quats with bacterial cytoplasmic membrane has been explained as an adsorption-like phenomenon. The reusability of highly active hexakis-quat against Staphylococcus aureus was studied and the activity was found to reduce after first cycle.

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Über Invertseifen I; die Einwirkung von Invertseifen auf Eiweiß‐Stoffe

Cited by 107 publications

References 15 publications

The Bactericidal Action of Synthetic Detergents

The Bactericidal Action of Synthetic Detergents

Interactions of Sodium Dodecyl Benzene Sulfonate and Sodium Dodecyl Sulfate with Gelatin: A Comparison

Antibacterial activity of novel insoluble bead‐shaped polymer‐supported multiquaternary ammonium salts

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