“…This hypothesis did not go uncontested and as early as 1904 Keitler suggested that the adverse effects of hysterectomy were in fact principally due to surgical interference with the ovarian blood supply. Ovarian abnormalities after hysterectomy were attributed by Holzbach (1906) and Vineburg (1915) to injury of the ovarian nerves sustained at operation. The idea that the removal of the uterus per se is without effect on ovarian function in women has recently been supported by the work of Whitelaw (1958) and others.…”