Ueber eine neue Darstellungsmethode und einige bemerkenswerte Eigenschaften der Salicylsäure

Evidence against specific binding of salicylic acid to plant catalase

“…~s shown in our contribution, SA binds to catalase present in different plant species, but also to catalase of fungal organisms [1,2] and at higher concentrations even to catalase from animals. Furthermore, it could be clearly demonstrated that SA-binding is a general property of iron-containing enzymes of plant and fungal origin.…”

“…We would predict that eventually it will be demonstrated that SA is induced as a result of pathogen attack in higher plants as a phytoalexin, a strongly antimicrobial agent, as has been known already for more than a hundred years [1].…”

“…l a 1874 Kolbe, who discovered an industrially useful method to ~ynthesize SA, called attention to its strong antimicrobial action [1]. SA in the following years became established as a ve1¢ successful food preservative and continued to be used on an appreciable scale until the 1950's.…”

“…These experiments and the derived mode of action of salicylate drew considerable attention (e.g. [2,1),11]).…”

Late complications of an ileal pouch

“…4 N 1828 Johann Andreas Buchner prepares salicin, a partially purified extract of willow bark. 5 N 1838 Raffaelle Piria splits salicin to yield salicylic acid 6. N 1859 Hammond Kolbe synthesises salicylic acid, with industrial scale production in 1874 7.…”