Ueber Schimmelvegetationen im thierischen Organismus

Grawitz, Paul

doi:10.1007/bf01996604

Cited by 17 publications

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“…He also studied the effects of fungi in animals. In 1880 he found that only after adaptation of the fung in cultures was it possible to repeat GrohC's and Block's experiments successfully [4]. During his leadership of the institute cryptococcosis was discovered and he himself was involved in it.…”

Section: Introductionmentioning

confidence: 99%

One hundred years ago: the history of crytococcosis in Greifswald. Medical mycology in the nineteenth century

Knoke

Schwesinger

1994

Mycoses

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Summary. Medico‐mycological investigations began at Greifswald in Germany as early as 1842 when Wilhelm Baum (1799–1883) was appointed to the chair of surgery of the university. This is shown by some theses of the time, as well as by the discovery of the contagious nature of pityriasis versicolor by Carl Ferdinand Eichstedt (1816‐92), who identified a fungus as the cause (1846), later named Microsporon furfur (C. Robin 1853). In 1868 the physician Karl Friedrich Mosler (1831–1911) published clinical‐mycological studies and investigations about animal feeding with yeasts. Seme time later (1870) Friedrich Grohé (1830‐86) and his assistants, Alwin R.A. Block (1843‐?) and M.R. Roth of the Pathological Institute, described the results of transmission studies with ‘Aspergillus glaucus, Penicillium glaucum and yeast’. His successor in the chair, Paul Grawitz (1850–1932), also published the results of his own mycological investigations. Finally, on 7 July 1894, at an evening lecture of the Greifswald Medical Society, Abraham Buschke (1868–1943) from the Hospital of Surgery gave a talk ‘on a peculiar disease caused by coccidia’, which was followed by a talk by the pathologist Otto Busse (1867–1922) on a ‘demonstration of a pathogenic coccidia species’. Busse's subsequent publications are the first proper descriptions of cryptococcosis (1894 ff.). However, Cryptococcus neoformans was named after F. Sanfelice, whose results were published later (1895). Zusammenfassung. Spätestens im Jahre 1842 begannen mit der Berufung Wilhelm Baums (1799–1883) an die Chirurgische Universitätsklinik medizin‐mykologische Untersuchungen in Greifswald. Davon zeugen Dissertationen sowie vor allem die Entdeckung des kontagiösen Charakters der Pityriasis versicolor durch Carl Ferdinand Eichstedt (1816–1892), der 1846 als Ursache jenen Pilz entdeckte, der 1853 von C. Robin Microsporon furfur genannt wurde. Klinisch‐mykologische Beobachtungen sowie Fütterungsversuche mit Pilzen an Tieren veröffentlichte 1868 der Internist Karl Friedrich Mosler (1831–1911). 1870 beschrieben Friedrich Grohé (1830–1886) und seine Assistenten Alwin R.A. Block (1843‐?) und M.R. Roth aus dem Pathologischen Institut ihre Ergebnisse von Übertragungsversuchen mit “Aspergillus glaucus, Penicillium glaucum, sowie von Hefe”. Auch der Nachfolger Paul Grawitz (1850–1932) hatte mykologische Untersuchungsergebnisse veröffentlicht. Schließlich trugen erstmalig am 7. Juli 1894 im Greifswalder Medizinischen Verein Abraham Buschke (1868–1943) aus der Chirurgischen Klinik “über eine eigenartige durch Coccidien hervorgerufene Krankheit” und der Pathologe Otto Busse (1867–1922) über die ‘Demonstration einer pathogenen Coccidienart’ vor. Die anschließenden Veröffentlichungen durch Busse sind die ersten Beschreibungen der Cryptococcose (1894 ff). Sie datieren vor denen von F. Sanfelice (1895), mit dem der Name Cryptococcus neoformans heute verknüpft wird.

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Section: Introductionmentioning

confidence: 99%