Uji Aktivitas Antibakteri Ekstrak Etanol Daun Benalu Langsat  (Dendropthoe sp) Terhadap Bakteri  Klebsiella Pneumoniae

Kurama, Greti M.; Maarisit, Wilmar; Karundeng, Einstein Z. Z. S.; Potalangi, Nerni O.

doi:10.55724/j.biofar.trop.v3i2.281

Cited by 5 publications

(5 citation statements)

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“…Phenolic compounds work as antimicrobials by coagulating or coagulating bacterial potoplasma to form a stable bond with bacterial proteins and in the digestive system, known tannins can eliminate toxins (Ngazizah et al, 2016). The results of this study are in line with the research conducted by Kurama et al (2020) on the antibacterial activity test of ethanol extract of benalu langsat leaves (Dendropthoe sp) against Klebsiella pneumoniae bacteria, which shows that secondary metabolites of saponins, flavonoids and tannins have the ability to damage bacterial cells.…”

Section: Finding and Discussionsupporting

confidence: 85%

Antibacterial actifity of kecombrang (Etlingera elatior) leaf ethanol extract to against Klebsiella pneumoniae

et al. 2022

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Infectious diseases caused by bacteria in generals can be cured using antibacterial. The use of antibacterials tends to cause local hypersensitivity either on the skin or mucous membranes so that their use is starting to be reduced. Therefore, the development of natural antibacterials made from plants to reduce resistance is very necessary. kecombrang (Etlingera elatior) is one of the plants that has been shown to have activity in inhibiting bacterial growth. This research is an experimental study that aims to determine the effectiveness of the ethanol extract of the leaves of kecombrang in inhibiting the growth of Klebsiella pneumoniae bacteria in vitro. The method used is the well method with a completely randomized design. The sample came from the Klebsiella pneumoniae bacteria culture. Kecombrang leaf ethanol extract was made in concentrations of 20%, 40%, 60%, 80% and 100%. The extract was tested on Klebsiella pneumoniae bacteria and observed for the formation of inhibition zones. Inhibition the results of the zone measuremens were then analyzed descriptively. The results showed kecombrang leaf ethanol extract 20%, 40%, 60%, 80%, and 100% produce inhibition zone diameter 1.9 mm; 2.6 mm; 7.7 mm; 12.1 mm; and 14.7 mm, 0.4 mm for the negative control and positive control 22.0 mm. Concentration 100% has better antibacterial ability due to higher compound content. The test results show the class of secondary metabolites kecombrang leaf ethanol extract contains flavonoids, tannin, and saponin. The conclusion of this study that the ethanol extract of kecombrang leaves has potential to inhibit the growth of Klebsiella pneumoniae bacteria.

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Section: Finding and Discussionsupporting

confidence: 85%

Antibacterial actifity of kecombrang (Etlingera elatior) leaf ethanol extract to against Klebsiella pneumoniae

et al. 2022

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“…Selain itu, adhesi bakteri terhadap inangnya juga dapat diinaktivasi oleh tanin. Tanin juga dapat menginaktifkan enzim, serta mengganggu transport protein, tanin juga dapat mengurangi motilitas bakteri (Kurama GM, 2020).…”

Section: Antibakteri Metabolit Sekunder Daun Saga Rambatunclassified

Pemanfaatan Daun Saga Rambat Sebagai Antibakteri

Shari

2024

IJHS

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Keanekaragaman hayati, termasuk hutan tropis di Indonesia banyak yang belum teridentifikasi. Kawasan hutan tersebut memiliki potensi tanaman obat yang tinggi. Pemanfaatan tanaman obat herbal sebagai pengobatan alternatif telah diterapkan sejak dahulu. Tanaman obat yang digunakan dengan tepat memiliki risiko kecil efek samping dibandingkan dengan obat-obatan berbahan dasar sintesis. Salah satu tanaman obat yang dapat dimanfaatkan adalah tanaman saga rambat (Abrus precatorius L) digunakan untuk mengatasi batuk, sariawan, radang tenggorokan, dan sakit gigi. Menurut beberapa penelitian, daun saga rambat (Abrus precatorius L) memiliki aktivitas antibakteri. Cara alternatif untuk mencegah resistensi bakteri adalah dengan pemberian antibakteri salah satunya dengan menggunakan tanaman herbal. Daun saga rambat (Abrus precatorius L) memiliki kandungan senyawa aktif seperti flavonoid, saponi, alkaloid, dan tannin yang bersifat sebagai antibakteri. Senyawa aktif dapat merusak dinding sel bakteri, mempengaruhi permeabilitas sel bakteri, mempengaruhi protein dan asam nukleat, serta menghambat kerja enzim.

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“…These small nanoparticles can change shape and release particles of silver ions. These ions penetrate the outer part of the bacteria and disrupt it, leading to the formation of new cells [24].…”

Section: Antibacterial Activity Testmentioning

confidence: 99%

Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus

Aulia,

Cahyaningrum

2023

J. Pijar.MIPA

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Binahong leaf is one of the medical plants that contain alkaloids, saponins, and flavonoids, which directly act as antibiotics. Additionally, chitosan and silver nanoparticles also possess antibacterial properties. This study aims to determine the antibacterial activity of a gel preparation against Staphylococcus aureus bacteria. It was a true experimental study with data collection carried out at the inorganic level. This study's results show that the gel preparation's organoleptic test meets the requirements for skin pH of 4.5-6.5. The spreading test meets the need for good distribution on the skin, which is 5-7cm. The antibacterial activity test showed that the largest diameter of the inhibition zone was observed at concentration F5 (5% binahong leaf extract), which was 13.4 mm.

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Uji Aktivitas Antibakteri Ekstrak Etanol Daun Benalu Langsat (Dendropthoe sp) Terhadap Bakteri Klebsiella Pneumoniae

Cited by 5 publications

References 0 publications

Antibacterial actifity of kecombrang (Etlingera elatior) leaf ethanol extract to against Klebsiella pneumoniae

Antibacterial actifity of kecombrang (Etlingera elatior) leaf ethanol extract to against Klebsiella pneumoniae

Pemanfaatan Daun Saga Rambat Sebagai Antibakteri

Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus

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