UJI AKTIVITAS FAGOSITOSIS  MAKROFAG  EKSTRAK ETANOL  DAUN SUJI (Dracaena angustifolia (Medik.)Roxb. ) SECARA  IN VITRO

Handayani, Nestri

doi:10.35799/pmj.1.1.2018.19648

Cited by 8 publications

(9 citation statements)

References 2 publications

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“…Most foreign substances that enter the tissue are eliminated through phagocytosis. Phagocytosis of macrophages is widely used as an immunological measure in assessing the health or function of the body's defense system (Handayani, 2018). Research conducted by Foysal et al (2020) reported that a combination of two or more probiotics, including Lactobacillus species, could improve the performance of the immune system of aquatic hosts.…”

Section: Discussionmentioning

confidence: 99%

THE EFFECT OF EM4 PROBIOTIC ADMINISTRATION FOR GROWTH AND SURVIVAL OF VANAME SHRIMP (Litopenaeus vannamei)

Wilisetyadi¹,

Setyowati

Azhar³

2022

jfh

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Vannamei shrimp is a shrimp that has high economic value in Indonesia. The poor aquatic environment can reduce shrimp growth rates and stress and cause death, and efforts to improve water quality by giving Probiotics EM4. Probiotic EM4 contains beneficial bacteria that can improve shrimp's digestive system, decompose organic matter in the waters, control the growth of pathogenic bacteria, and improve water quality. The experimental parameters included total hemocyte count (THC), differential hemocyte count (DHC) consisting of hyaline cells, granule cells, and semi-granule cells, and phagocytic activity (AF). The study was carried out for 69 days using vanamei shrimp with PL 30. This study used four treatments and three replications, namely treatment P0 (without giving probiotic EM4), P1 (giving probiotic EM4 at a dose of 0.5 ml/L), P2 (giving probiotic EM4 at a dose of 1.5 ml/ L), P3 (giving probiotic EM4 dose of 2.5 ml/L). The study's results proved that the administration of probiotic EM4 on the maintenance medium had a significant effect (P<0.05) on THC, DHC, and AF. At THC, the highest value was at P3 with a value of 19.44 x 10 6 cells/ml, and the lowest was at P0 with a value of 11.01 x 10 6 cells/ml, then the DHC values such as hyaline cells ranged from 51.34 – 65.81%, granule cells ranged from 21.33 – 30.4%, semi-granular cells ranged from 12.84 – 18.24%. And then for the highest AF value at P3 with a value of 67.97% and the lowest P0 with a value of 49.34%

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Section: Discussionmentioning

confidence: 99%

THE EFFECT OF EM4 PROBIOTIC ADMINISTRATION FOR GROWTH AND SURVIVAL OF VANAME SHRIMP (Litopenaeus vannamei)

Wilisetyadi¹,

Setyowati

Azhar³

2022

jfh

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“…7 Makrofag adalah sel yang berperan penting dalam sistem imunitas tubuh untuk melawan patogen dengan cara fagositosis. 7,8 Fagositosis ini dapat memicu aktivasi makrofag untuk mensintesis berbagai mediator inflamasi, antara lain interleukin 1 (IL-1) dan tumor necrosis factor-α (TNF-α). 8 Mediator-mediator tersebut menjadikan makrofag sebagai pertahanan tubuh yang kuat, tetapi apabila makrofag teraktivasi secara berlebihan justru dapat menyebabkan kerusakan jaringan.…”

Section: Pendahuluanunclassified

“…7,8 Fagositosis ini dapat memicu aktivasi makrofag untuk mensintesis berbagai mediator inflamasi, antara lain interleukin 1 (IL-1) dan tumor necrosis factor-α (TNF-α). 8 Mediator-mediator tersebut menjadikan makrofag sebagai pertahanan tubuh yang kuat, tetapi apabila makrofag teraktivasi secara berlebihan justru dapat menyebabkan kerusakan jaringan. 7 Limfosit merupakan sel inflamasi kronis yang bersifat spesifik sebagai respons imun host terhadap adanya suatu jejas saat terjadi inflamasi yang bersifat kronis.…”

Section: Pendahuluanunclassified

<p>Efek pemberian seduhan kopi robusta (Coffea canephora) terhadap jumlah sel makrofag dan limfosit pada model tikus periodontitis kronis</p><p>The effect of brewed robusta coffee (Coffea canephora) on macrophage and lymphocyte cells in rat model of chronic periodontitis<p>

Prasetya

Praharani

Fatimatuzzahro

et al. 2021

Padjadjaran J Dent Res Students

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“…Plants that contain metabolite compounds can help the wound healing process (Fernandes, Maharani, Sunarta, & Rayan, 2018;Handayani, Sundu, & Karapa, 2017;Wijonarko, Anies, & Mardiono, 2016). The content of active substances such as flavonoids, saponins, and polyphenols in the kecombrang Sedian leaf extract gel is effective in healing rabbits' cut wounds (Ruslim, Anitasari, Ismail, Oli, & Yani, 2017).…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of Ethanol Extract in Muli Banana Peels (Musa Acuminata) to Heal Cut Wounds in Mice (Mus Musculus L.)

Maulidya

Kanedi

Yulianty

et al. 2020

Biosfer

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Muli banana peels contain flavonoids, saponins, and tannins that foster the process of wound healing. The purpose of this study was to determine the effect of ethanol extract in muli banana peels (Musa acuminata) on cut wounds healing process in mice (Mus musculus). The study design was the completely randomized design by using 24 male mice which were divided into 6 groups, namely (K+, K-, P1, P2, P3, and P4). Each treatment consisted of 4 mice. All groups of mice were treated with a 1 cm cut wound on the back. The K+ group as the positive control group were applied with povidone-iodine, the K- group as the negative control group were applied with distilled water, the P1 group was applied with a concentration of 10% extract, the P2 group with 20% extract, the P3 group with 30% extract, and the P4 group with 40% extract for 14 days. On the 15th day, histological slides were made by taking 1 sample from each group. The results showed that the ethanol extract of muli banana peels played a role in the cut wound healing process. Uji Efektivitas Ekstrak Etanol Kulit Buah Pisang Muli (Musa Acuminata) Terhadap Penyembuhan Luka Sayat Pada Mencit (Mus Musculus L.)Abstrak: Kulit buah pisang muli mengandung senyawa flavonoid, saponin dan tanin yang memiliki peranan dalam proses penyembuhan luka. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak etanol kulit buah pisang muli (Musa acuminata) terhadap proses penyembuhan luka sayat pada mencit (Mus musculus). Rancangan penelitian yang digunakan adalah rancangan acak lengkap, menggunakan 24 ekor mencit jantan yang dibagi menjadi 6 kelompok yaitu (K+, K-, P1, P2, P3, P4) dengan masing- masing perlakuan terdiri dari 4 mencit. Semua kelompok mencit diberi perlakuan luka pada punggung sepanjang 1 cm. Kelompok K+ sebagai kontrol positif dioleskan povidone iodine, kelompok K- sebagai kontrol negatif dioleskan aquades, kelompok P1 dioleskan ekstrak konsentrasi 10%, kelompok P2 dioleskan ekstrak konsentrasi 20%, kelompok P3 dioleskan ekstrak konsentrasi 30%, dan kelompok P4 dioleskan ekstrak konsentrasi 40% selama 14 hari. Pembuatan preparat histologi dilakukan pada hari ke 15 dengan mengambil 1 sampel dari tiap kelompok. Hasil penelitian menunjukan bahwa ekstrak etanol kulit buah pisang muli berperan dalam proses penyembuhan luka sayat yang dilihat dari gambaran histologi lebih baik dibandingkan kelompok kontrol.

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UJI AKTIVITAS FAGOSITOSIS MAKROFAG EKSTRAK ETANOL DAUN SUJI (Dracaena angustifolia (Medik.)Roxb. ) SECARA IN VITRO

Cited by 8 publications

References 2 publications

THE EFFECT OF EM4 PROBIOTIC ADMINISTRATION FOR GROWTH AND SURVIVAL OF VANAME SHRIMP (Litopenaeus vannamei)

THE EFFECT OF EM4 PROBIOTIC ADMINISTRATION FOR GROWTH AND SURVIVAL OF VANAME SHRIMP (Litopenaeus vannamei)

<p>Efek pemberian seduhan kopi robusta (Coffea canephora) terhadap jumlah sel makrofag dan limfosit pada model tikus periodontitis kronis</p><p>The effect of brewed robusta coffee (Coffea canephora) on macrophage and lymphocyte cells in rat model of chronic periodontitis<p>

The Effectiveness of Ethanol Extract in Muli Banana Peels (Musa Acuminata) to Heal Cut Wounds in Mice (Mus Musculus L.)

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