Uji Daya Larvasida Ekstrak Aseton Dan Etanol Kulit Buah Kakao (Theobroma cacao L.) Terhadap Larva Aedes aegypti

Chusniasih, Dewi; Ulfa, Ade Maria; Kurniawan, Agung

doi:10.33024/jfm.v4i2.5313

Cited by 5 publications

(5 citation statements)

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“…Daya lekat menggambarkan kemampuan sediaan untuk menempel pada lapisan kulit. Semakin besar kemampuan gel melekat semakin baik penghantaran obatnya (Chusniasih et al, 2022).…”

Section: Hasil Uji Daya Lekatunclassified

Pembuatan Sediaan Gel Anti Acne dari Asap Cair Tempurung Kelapa Berbasis Galaktomanan dengan Bakteri Staphylococcus aureus

Zebua,

Yulia,

Zulkarnain

2023

jharma

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Liquid smoke is a condensate liquid resulting from coconut shell pyrolysis which contains the main constituents of acids, phenols and carbonyls, so it is widely applied as a natural preservative in food and as an anti-bacterial. Gel preparations are preferred because when used they leave a translucent, elastic layer, good drug release and an attractive appearance. This study aims to determine whether liquid smoke can be formulated into an acne gel dosage form on a galactomannan basis which at certain concentrations has antimicrobial activity againstStaphylococcus aureus and does not cause skin irritation. This research was conducted using experimental and descriptive methods. Beginning with collecting literature information related to the content of liquid smoke from coconut shells, then making a galactomannan base, formulation of acne gel preparations from liquid smoke, making microbiological media, methods of testing antimicrobial activity, examining the physical quality of preparations including preparation homogeneity, testing the preparation's pH, testing preparation stability, and irritation test on volunteers. Based on the results of the study, it was shown that liquid smoke can be formulated into an acne gel dosage form based on galactomannan. Homogeneity test results on gel preparations remained homogeneous, the pH obtained remained stable, skin irritation test results did not cause irritation, preparation viscosity test results obtained between 4520-9990 mPas, gel preparation test on growthStaphylococcus aureus at a concentration of 5% gives an inhibition of 15.3 mm and the results of the antibacterial activity test on liquid smoke can inhibit growthStaphylococcus aureus in the minimum range of 12.5 mg/ml gives an inhibitory diameter of 7.0 mm which is included in the medium category.

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“…Daya lekat menggambarkan kemampuan sediaan untuk menempel pada lapisan kulit. Semakin besar kemampuan gel melekat semakin baik penghantaran obatnya (Chusniasih et al, 2022).…”

Section: Hasil Uji Daya Lekatunclassified

Pembuatan Sediaan Gel Anti Acne dari Asap Cair Tempurung Kelapa Berbasis Galaktomanan dengan Bakteri Staphylococcus aureus

Zebua,

Yulia,

Zulkarnain

2023

jharma

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“…Proses maserasi dilakukan dengan menggunakan pelarut etanol 96% sampai terjadi perubahan warna pada pelarut menjadi bening. Penggunaan pelarut etanol 96% karena memiliki sifat yang lebih selektif, absorbsinya baik, mudah menguap sehingga ekstrak kental yang didapat lebih cepat (Chusniasih et al, 2021).…”

Section: Pengujian Aktivitas Tabir Suryaunclassified

UJI AKTIVITAS TABIR SURYA EKSTRAK DAN FRAKSI AKTIF BAJAKAH TAMPALA (Spatholobus Littoralis Hassk.)

2022

Endurance

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Bajakah Tampala (Spatholobus littoralis Hassk.) salah satu tumbuhan endemik Indonesia berasal dari Kalimantan Tengah yang telah terbukti mengandung metabolit sekunder yaitu flavonoid. Flavonoid memiliki potensi sebagai tabir surya. Senyawa tabir ini memiliki manfaat untuk menjaga kulit dari efek sinar ultraviolet yang dipancarkan oleh matahari. Tujuan penelitian ini untuk menentukan aktivitas tabir surya dari ekstrak dan fraksi bajakah tampaladengan metode in vitro yang menggunakan alat spektrofotometri UV-Vis untuk mengetahui nilai Sun Protection Factor (SPF). Ekstraksi bajakah tampala menggunakan cara maserasi dengan etanol 96% danfraksinasi menggunakan cara ekstraksi cair-cair dengan n-heksan, etil asetat, butanol, dan air. Penentuan aktivitas tabir surya menggunakan konsentrasi 0,05%, 0,1%, dan 0,5%.Hasilmembuktikan bahwa ekstrak, fraksi etil asetat, dan n-heksan pada konsentrasi 0,1% mempunyai nilai SPF diatas 15, yaitu 21,53; 15,61; dan 17,05 dengan proteksi ultra yang menunjukkan nilai SPF lebih tinggi dibandingkan fraksi butanol dan fraksi air. Analisis data nilai SPF ekstrak dan fraksi diperoleh P-value < 0,05.

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“…Cocoa pod skin has antibacterial activity against Propionibacterium acnes and Staphylococcus epidermidis and is also antiparasitic (Adha & Ibrahim, 2021;Lestari et al, 2021;Pappa et al, 2019). Cocoa shell extract has strong antioxidant activity with an IC50 value of 17.21 ppm (Hidayah et al, 2021;Priani et al, 2021;Ulfa et al, 2019) and has sunscreen activity (Khoiriyah et al, 2022;Priani et al, 2021). Cocoa shell extract can be used as a potentially good raw material for medicine (Septriyanti et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

“…Cocoa shell extract can be used as a potentially good raw material for medicine (Septriyanti et al, 2020). Cocoa shell extract has been widely used in cosmetic preparations, including emulgel preparations (Fahleni et al, 2021;Priani et al, 2021), gel mask preparations (Ulfa et al, 2019), serum preparations (Hidayah et al, 2021) and cream preparations (Huda et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

FORMULATION OF PEEL-OFF GEL MASK OF COCOA SKIN EXTRACT (Theobroma cacao L) WITH VARIED CONCENTRATION GELLING AGENT

Sari,

Purwanto,

Nafisah

2024

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Cocoa shells are waste from the plantation industry, with a fairly good potential source of energy and protein. The ethanol extract of cocoa shells contains alkaloids, flavonoids, phenols, and tannins. Cocoa shell extract has strong antioxidant activity with an IC50 value of 17.21 ppm and has sunscreen activity. This study aimed to determine the formulation and physical test of a peel-off gel mask with cocoa shell extract (Theobroma cacao L) and to determine its effect. The research method used was an experimental method with variations in the concentration of a combination of HPMC and PVA of 2%:10%, 3%:9%, 4%:8%, 5%:7%, and 0%:12%. The physical tests used on the peel-off gel mask with cocoa shell extract (Theobroma cacao L) included organoleptic, homogeneity, pH, spreadability, drying time, adhesiveness, viscosity, and cycling tests. Based on the results of the research carried out, peel-off gel mask has the characteristics of a brown color, a distinctive extract smell and a thick texture, homogeneous for F1 and F5, and not homogeneous for F2, F3, and F4, sticking force 4.53±0.24 seconds; 5.45±0.36 seconds; 8.94±0.64 seconds; 11.23±0.72 seconds; 3.87±0.70 seconds; spreadability 3.99 ± 0.18 cm; 3.33±0.31 cm; 3.47±0.78 cm; 3.32±0.50 cm; 3.05±0.42 cm; pH 6.17 ± 0.10; 6.16±0.03; 6.15±0.10; 6.11±0.05; 6.42±0.03; viscosity 19481.10±201.10; 20165.50±1.05; 20165.73±2.02; 20182.53±9.47; 14618.40±158.48. The physical stability of the gel mask preparations after treatment showed that the results of the peel-off gel mask preparations, F1 and F5, were stable. Keywords: peel-off gel mask, cocoa shell, extract, gelling agent

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Uji Daya Larvasida Ekstrak Aseton Dan Etanol Kulit Buah Kakao (Theobroma cacao L.) Terhadap Larva Aedes aegypti

Cited by 5 publications

References 0 publications

Pembuatan Sediaan Gel Anti Acne dari Asap Cair Tempurung Kelapa Berbasis Galaktomanan dengan Bakteri Staphylococcus aureus

Pembuatan Sediaan Gel Anti Acne dari Asap Cair Tempurung Kelapa Berbasis Galaktomanan dengan Bakteri Staphylococcus aureus

UJI AKTIVITAS TABIR SURYA EKSTRAK DAN FRAKSI AKTIF BAJAKAH TAMPALA (Spatholobus Littoralis Hassk.)

FORMULATION OF PEEL-OFF GEL MASK OF COCOA SKIN EXTRACT (Theobroma cacao L) WITH VARIED CONCENTRATION GELLING AGENT

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